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Title
Biotransformations in organic chemistry : a textbook.
Edition
7th ext. and cor. ed.
ISBN
9783319615905 (electronic book)
3319615904 (electronic book)
9783319615899
3319615890
Publication Details
Cham : Springer, ©2018.
Language
English
Description
1 online resource
Item Number
10.1007/978-3-319-61590-5 doi
Call Number
TP248.65.E59
Dewey Decimal Classification
660.6/34
Summary
This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts-principles of stereoselective transformations, enzyme properties and kinetics -- the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C- bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques, artificial enzymes and the design of cascade-reactions are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this 7th edition new topics have been introduced which include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also emphasizes the use of enzymes in industrial biotransformations with practical examples.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Description based on print version record.
Introduction
Common Prejudices Against Enzymes
Advantages and Disadvantages of Biocatalysts. Enzyme Properties and Nomenclature
Biocatalytic Applications: Hydrolytic Reactions
Reduction Reactions
Oxidation Reactions.- Formation of Carbon-Carbon Bonds
Addition and Elimination Reactions
Transfer Reactions
Halogenation and Dehalogenation Reactions
Special Techniques: Enzymes in Organic Solvents
Cascade Reactions
Immobilization.- Artificial and Modified Enzymes
State of the Art and Outlook
Appendix: Basic Rules for Handling Biocatalysts
Abbreviations
Suppliers of Enzymes
Commonly Used Enzyme Preparations
Major Culture Collections
Pathogenic Bacteria and Fungi
Index.
