@article{826450,
      recid = {826450},
      author = {Machida, Masafumi, and Weinstein, Stuart L., and  Dubousset, Jean,},
      title = {Pathogenesis of idiopathic scoliosis /},
      pages = {1 online resource (ix, 188 pages) :},
      abstract = {This book provides comprehensive coverage of current  topics in idiopathic scoliosis (IS). A three-dimensional  deformity of the spine, the condition is characterized by  lateral curvature combined with vertebral rotation. The  primary lesion, however, lies in the median sagittal plane,  taking the form of a lordosis. Although the clinical  manifestations of scoliosis have been well documented, its  cause and pathogenesis have not yet been determined.  Research into what causes IS has focused on the structural  elements of the spine, spinal musculature, collagenous  structures, the endocrine system, the central nervous  system, and genetics. Results of these studies have brought  about a new perception of IS epiphenomena, but the main  cause of IS remains unknown. Recently, several  investigators have produced new hypotheses regarding the  cause of IS using the developing techniques of genetics,  biochemistry, and neurology. This book is a review of the  various causative factors thus far proposed for IS and an  introduction to the directions in which research is heading  to determine the primary cause of IS.},
      url = {http://library.usi.edu/record/826450},
      doi = {https://doi.org/10.1007/978-4-431-56541-3},
}