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000826623 019__ $$a1022948891$$a1023734209$$a1024088717$$a1028188846
000826623 020__ $$a9783662561799
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000826623 0247_ $$a10.1007/978-3-662-56179-9$$2doi
000826623 035__ $$aSP(OCoLC)on1027060550
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000826623 050_4 $$aRD92-97.8
000826623 050_4 $$aRD701-811
000826623 08204 $$a617.1$$223
000826623 1001_ $$aFu, Xiaobing,$$eauthor.
000826623 24510 $$aCellular Dedifferentiation and Regenerative Medicine /$$cby Xiaobing Fu, Andong Zhao, Tian Hu.
000826623 264_1 $$aBerlin, Heidelberg :$$bSpringer Berlin Heidelberg :$$bImprint :$$bSpringer,$$c2018.
000826623 300__ $$a1 online resource (xii, 291 pages) :$$billustrations
000826623 336__ $$atext$$btxt$$2rdacontent
000826623 337__ $$acomputer$$bc$$2rdamedia
000826623 338__ $$aonline resource$$bcr$$2rdacarrier
000826623 347__ $$atext file$$bPDF$$2rda
000826623 504__ $$aIncludes bibliographical references and index.
000826623 5050_ $$aA brief history of Regeneration -- The origin of cells in Regeneration -- Cell dedifferentiation -- Cell transdifferentiation -- Cell reprogramming -- Dedifferentiation vs Transdifferentiation vs Reprogramming -- The extent of cell dedifferentiation -- Maintenance of cell differentiated identity -- Unstable differentiated state -- Epidermal cell dedifferentiation and skin regeneration -- Peripheral nerve regeneration and Schwann cell dedifferentiation -- Central nervous system and dedifferentiation -- Dedifferentiation and Heart -- Dedifferentiation and Kidney -- Dedifferentiation and other 4 systems -- The relationship between cell dedifferentiation and development of cancer and several diseases.
000826623 506__ $$aAccess limited to authorized users.
000826623 520__ $$aThis book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications. The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine. The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.
000826623 650_0 $$aMedicine.
000826623 650_0 $$aDermatology.
000826623 650_0 $$aTraumatology.
000826623 650_0 $$aRegenerative medicine.
000826623 650_0 $$aTissue engineering.
000826623 7001_ $$aZhao, Andong,$$eauthor.
000826623 7001_ $$aHu, Tian,$$eauthor.
000826623 77608 $$iPrint version: $$z9783662561775
000826623 852__ $$bebk
000826623 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-662-56179-9$$zOnline Access$$91397441.1
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000826623 980__ $$aEBOOK
000826623 980__ $$aBIB
000826623 982__ $$aEbook
000826623 983__ $$aOnline
000826623 994__ $$a92$$bISE