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000826630 019__ $$a1023425946$$a1023776729$$a1024161873$$a1024238720$$a1028224660
000826630 020__ $$a9783319720029
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000826630 020__ $$z9783319720012
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000826630 0247_ $$a10.1007/978-3-319-72002-9$$2doi
000826630 035__ $$aSP(OCoLC)on1027063577
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000826630 049__ $$aISEA
000826630 050_4 $$aRS400-431
000826630 08204 $$a615.19$$223
000826630 1001_ $$aRams-Baron, Marzena,$$eauthor.
000826630 24510 $$aAmorphous Drugs :$$bBenefits and Challenges /$$cby Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch.
000826630 264_1 $$aCham :$$bSpringer International Publishing :$$bImprint :$$bSpringer,$$c2018.
000826630 300__ $$a1 online resource (ix, 230 pages) :$$billustrations
000826630 336__ $$atext$$btxt$$2rdacontent
000826630 337__ $$acomputer$$bc$$2rdamedia
000826630 338__ $$aonline resource$$bcr$$2rdacarrier
000826630 347__ $$atext file$$bPDF$$2rda
000826630 504__ $$aIncludes bibliographical references and index.
000826630 5050_ $$aWhy amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability -- a key problem of amorphous drugs -- Amorphous drug formulation.
000826630 506__ $$aAccess limited to authorized users.
000826630 520__ $$aThis book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.
000826630 650_0 $$aChemistry.
000826630 650_0 $$aPharmaceutical technology.
000826630 650_0 $$aPharmaceutical chemistry.
000826630 650_0 $$aThermodynamics.
000826630 650_0 $$aPhase transformations (Statistical physics)
000826630 650_0 $$aBiomedical engineering.
000826630 650_0 $$aCeramics.
000826630 650_0 $$aGlass.
000826630 650_0 $$aComposite materials.
000826630 7001_ $$aJachowicz, Renata,$$eauthor.
000826630 7001_ $$aBoldyreva, Elena,$$eauthor.
000826630 7001_ $$aZhou, Deliang,$$eauthor.
000826630 7001_ $$aJamroz, Witold,$$eauthor.
000826630 7001_ $$aPaluch, Marian,$$eauthor.
000826630 77608 $$iPrint version: $$z9783319720012
000826630 852__ $$bebk
000826630 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-72002-9$$zOnline Access$$91397441.1
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000826630 980__ $$aEBOOK
000826630 980__ $$aBIB
000826630 982__ $$aEbook
000826630 983__ $$aOnline
000826630 994__ $$a92$$bISE