@article{827270,
      recid = {827270},
      author = {Imbach, Paul,},
      title = {Antibody therapy : substitution -- immunomodulation --  monoclonal immunotherapy /},
      pages = {1 online resource.},
      abstract = {This practical manual, written by well-known experts,  reviews current indications for the use of IgG concentrates  and some other modern immunomodulators and provides  fundamental information on present-day immunomodulation in  patients (and mice). The book opens by tracing the  transition from IgG substitution to IgG immunomodulation  and providing expert updates on immunomodulatory  indications in autoimmune and inflammatory disorders,  including hematologic, neurologic, dermatologic, and other  diseases. Basic aspects of IgG concentrates, including  methods of production, safety, currently available  products, and mechanisms of action, are then discussed. An  entire chapter is devoted to the different aspects of  immunomodulatory IgG treatment in the bleeding disorder  immune thrombocytopenia (ITP). Finally, the transition from  polyclonal to monoclonal antibody (mAb) treatment is  addressed in detail, covering mAb development, methods,  mechanisms of action, adverse effects, and more. Particular  attention is paid to the example of anti-CD20 (B-cell)  antibody.},
      url = {http://library.usi.edu/record/827270},
      doi = {https://doi.org/10.1007/978-3-319-68038-5},
}