000827414 000__ 05985cam\a2200553Ii\4500 000827414 001__ 827414 000827414 005__ 20230306144513.0 000827414 006__ m\\\\\o\\d\\\\\\\\ 000827414 007__ cr\cn\nnnunnun 000827414 008__ 170922s2017\\\\sz\\\\\\ob\\\\000\0\eng\d 000827414 019__ $$a1004760116$$a1008876782$$a1011949961$$a1013719646 000827414 020__ $$a9783319532196$$q(electronic book) 000827414 020__ $$a3319532197$$q(electronic book) 000827414 020__ $$z9783319532189 000827414 020__ $$z3319532189 000827414 0247_ $$a10.1007/978-3-319-53219-6$$2doi 000827414 035__ $$aSP(OCoLC)on1004563584 000827414 035__ $$aSP(OCoLC)1004563584$$z(OCoLC)1004760116$$z(OCoLC)1008876782$$z(OCoLC)1011949961$$z(OCoLC)1013719646 000827414 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dEBLCP$$dGW5XE$$dN$T$$dYDX$$dNJR$$dAZU$$dUPM$$dOCLCF$$dCOO$$dCOD$$dMERER$$dSNK$$dOCLCQ$$dCAUOI$$dOCLCQ 000827414 049__ $$aISEA 000827414 050_4 $$aSF895 000827414 08204 $$a636.089/68$$223 000827414 24500 $$aCanine and feline dementia :$$bmolecular basis, diagnostics and therapy /$$cGary Landsberg, Aladár Mad̕ari, Norbert Žilka, editors. 000827414 264_1 $$aCham, Switzerland :$$bSpringer,$$c2017. 000827414 300__ $$a1 online resource 000827414 336__ $$atext$$btxt$$2rdacontent 000827414 337__ $$acomputer$$bc$$2rdamedia 000827414 338__ $$aonline resource$$bcr$$2rdacarrier 000827414 347__ $$atext file$$bPDF$$2rda 000827414 504__ $$aIncludes bibliographical references. 000827414 5050_ $$aPreface; Canine Dementia: Unbearable Lightness of Ageing; Acknowledgements; Contents; 1: Clinical Picture of Canine and Feline Cognitive Impairment; 1.1 Clinical Signs of Cognitive Dysfunction; 1.2 Prevalence of Behavior Signs in Senior Pets; 1.3 Pet Owner Reporting; 1.4 Diagnosis; 1.5 Senior Cognition and Decline in Learning and Memory; 1.6 Neuropsychological and Behavioral Assessment; 1.7 Summary; References; 2: Behavioural and Medical Differentials of Cognitive Decline and Dementia in Dogs and Cats; 2.1 Differential Diagnosis of CDS. 000827414 5058_ $$a2.1.1 Behavioural Differentials of CDS in Dogs and Cats2.1.1.1 Anxiety; 2.1.1.2 Fear; 2.1.1.3 Night-Time Waking; 2.1.1.4 Excessive Vocalisation; 2.1.1.5 House Soiling; 2.1.1.6 Aggression; 2.1.1.7 Repetitive Behaviours; 2.1.2 Medical Differentials of CDS in Dogs and Cats; 2.1.2.1 Sensory Decline; 2.1.2.2 Pain; 2.1.2.3 Cardiovascular Disease; 2.1.2.4 Endocrine Disease; 2.1.2.5 Gastrointestinal Disease; 2.1.2.6 Urinary System Disease; 2.1.3 Neurological Differentials of CDS in Dogs and Cats; 2.2 Diagnostic Approach to Reach a Presumptive Diagnosis of CDS; 2.2.1 Signalment. 000827414 5058_ $$a2.2.2 History Taking2.2.2.1 Disorientation; 2.2.2.2 Alterations in Interactions with Owners, Other Pets and the Environment; 2.2.2.3 House Soiling; 2.2.2.4 Changes in Activity; 2.2.2.5 Establishment of the Most Relevant Complaint(s); 2.2.3 Patient Examination; 2.2.3.1 Physical Examination; 2.2.3.2 Orthopaedic Examination; 2.2.3.3 Ophthalmological Examination; 2.2.3.4 Neurological Examination; 2.2.3.5 Changes on Neurological Examination that Would Not Be Expected with CDS; 2.2.4 Problem List and Differential Diagnosis; 2.2.4.1 Problem List; 2.2.4.2 Differential List. 000827414 5058_ $$a2.2.4.3 Differential Diagnosis: DAMNITV2.2.4.4 Degenerative Differentials; Ceroid Lipofuscinosis; L-2-Hydroxyglutaric Aciduria; Other Neurodegenerative Diseases; 2.2.4.5 Anomalous: Brain Malformations; 2.2.4.6 Metabolic Differentials; Hypoglycaemia; Hepatic Encephalopathy; Renal Encephalopathy; Electrolytes Disturbances; 2.2.4.7 Nutritional; Vitamin B1 Deficiency; Vitamin E Deficiency; 2.2.4.8 Neoplastic Brain Disease; 2.2.4.9 Inflammatory Non-infectious Brain Disease; 2.2.4.10 Infectious Brain Disease; 2.2.4.11 Traumatic Differential: Chronic Repetitive Traumatic Brain Injury. 000827414 5058_ $$a2.2.4.12 Toxic Differential: Lead Poisoning2.2.4.13 Vascular; Hypertensive Encephalopathy; Cerebrovascular Accidents; 2.2.5 Diagnostic Testing; 2.2.5.1 Laboratory Testing; 2.2.5.2 Blood Pressure; 2.2.5.3 Advanced Imaging; 2.2.5.4 CSF Analysis; 2.2.5.5 Additional Testing; 2.2.6 Summary; References; 3: Phenotypic Variability and Clinical Staging of Canine Dementia; 3.1 The Clinical Picture of Canine Dementia in a Nutshell; 3.1.1 Disorientation and Activity Changes; 3.1.2 Changes in Social Interactions; 3.1.3 Sleep and Wakefulness Cycle Changes; 3.1.4 Changes in Hygiene Habits. 000827414 506__ $$aAccess limited to authorized users. 000827414 520__ $$aThe book deeply focuses on the epidemiology, diagnostics, therapy and molecular basis of canine and feline dementia or cognitive dysfunction syndrome. The aim is to provide a broad overview of the current knowledge on canine and feline dementia. Experiences of clinicians are appropriately linked with current scientific knowledge in a readily comprehensible form. In the first three chapters we describe the clinical pictures of canine and feline dementia, discuss the medical causes of the disease and its phenotypic variability. In the 4th chapter we introduce the dog as an appropriate animal model for human Alzheimer's disease progression. Then we shed light on the neuropathological hallmarks of canine and feline dementia. For the first time we touch upon the modern diagnostic approaches based on the neuroproteomic technological progress. Last but not least, we address the current pharmacological and non-pharmacological approaches for therapy and risk and protective factors of feline and canine dementia. The book addresses clinicians, researchers, university teachers and graduate students in veterinary neurology and medicine. 000827414 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 4, 2017). 000827414 650_0 $$aVeterinary neurology. 000827414 650_0 $$aDogs$$xDiseases. 000827414 650_0 $$aCats$$xDiseases. 000827414 7001_ $$aLandsberg, Gary M.,$$eeditor. 000827414 7001_ $$aMaďari, Aladár,$$eeditor. 000827414 7001_ $$aŽilka, Norbert,$$eeditor. 000827414 77608 $$iPrint version: $$z9783319532189 000827414 852__ $$bebk 000827414 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-53219-6$$zOnline Access$$91397441.1 000827414 909CO $$ooai:library.usi.edu:827414$$pGLOBAL_SET 000827414 980__ $$aEBOOK 000827414 980__ $$aBIB 000827414 982__ $$aEbook 000827414 983__ $$aOnline 000827414 994__ $$a92$$bISE