000838614 000__ 04610cam\a2200469Ii\4500 000838614 001__ 838614 000838614 005__ 20230306144552.0 000838614 006__ m\\\\\o\\d\\\\\\\\ 000838614 007__ cr\un\nnnunnun 000838614 008__ 180416s2018\\\\nyua\\\\o\\\\\001\0\eng\d 000838614 020__ $$a9781493971930$$q(electronic book) 000838614 020__ $$a149397193X$$q(electronic book) 000838614 020__ $$z9781493971916 000838614 020__ $$z9781493971923 000838614 0247_ $$a10.1007/978-1-4939-7193-0$$2doi 000838614 035__ $$aSP(OCoLC)on1031374838 000838614 035__ $$aSP(OCoLC)1031374838 000838614 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dAZU$$dOCLCF$$dUPM$$dCOO$$dUAB 000838614 049__ $$aISEA 000838614 050_4 $$aRC280.P25 000838614 08204 $$a616.99/437$$223 000838614 24500 $$aPancreatic cancer /$$cJohn P. Neoptolemos, Raul Urrutia, James L. Abbruzzese, Markus W. Büchler, editors. 000838614 250__ $$aSecond edition. 000838614 264_1 $$aNew York, NY :$$bSpringer,$$c2018. 000838614 300__ $$a1 online resource :$$billustrations. 000838614 336__ $$atext$$btxt$$2rdacontent 000838614 337__ $$acomputer$$bc$$2rdamedia 000838614 338__ $$aonline resource$$bcr$$2rdacarrier 000838614 500__ $$aIncludes index. 000838614 5050_ $$aSection: The Nature of Pancreatic Cancer -- Cell Cycle Machinery and Its Alterations in Pancreatic Cancer -- Animal modelling of Pancreatitis-to-Cancer Progression -- Stromal Inflammation in Pancreatic Cancer: Mechanisms and Translational Applications -- Familial Pancreatic Cancer -- Section: Clinical Management of Pancreatic Cancer -- Therapeutic Endoscopy in the Management of Pancreatic Cancer -- Controversies in Pathology Reporting and Staging -- Staging and Postoperative Outcomes Using the International Study Group of Pancreatic Surgery (ISGPS) Classifications -- Borderline Respectable Pancreatic Cancer -- New Japanese Classification of Pancreatic Cancer -- Arterial Resection in Pancreatic Cancer -- Treatment of Recurrent Pancreatic Cancer After Surgery -- Neoadjuvant Chemotherapy in Pancreatic Cancer -- Differential Therapy Based on Tumor Heterogeneity in Pancreatic Cancer -- Neoadjuvant Chemoradiation for Operable Pancreatic Cancer: the Importance of Local Disease Control -- Section: New Directions -- Development of Novel Therapeutic Response Biomarkers -- Clinical Applications of Genomics and Proteomics in Pancreatic Cancer -- Approaching Pancreatic Cancer Phenotypes via Metabolomics -- Circulating Tumour Cells -- Cancer Exosomes for Early Pancreatic Cancer Diagnosis and Role Metastasis -- Metabolism in Pancreatic Cancer -- Secondary Screening for Inherited Pancreatic Ductal Adenocarcinoma -- Role of Radiotherapy in Locally Advanced Pancreatic Cancer -- Evolution of Pancreatic Cancer Surgery -- Multiparameter Modalities for the Study of Patients in the Setting of Individualized Medicine -- Epigenetic Pharmacology -- Precision Medicine Based on Next Generation Sequencing and Master Controllers. 000838614 506__ $$aAccess limited to authorized users. 000838614 520__ $$aIn organizing the second edition of this renowned Handbook, Dr. Neoptolemos and his co-editors have produced and updated a revised edition to the distinguished Major Reference Work devoted to pancreatic cancer. Like its preceding edition, the second edition continues to have a widespread appeal among clinicians, pathologists and basic scientists, who are now struggling to understand this complex and rapidly expanding field. Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer, (there is currently an unprecedented investment by academia and industry in this field), each research’s knowledge of other specialty areas outside his or her own is often quite limited. The aim of the new edition is to place the tangible advances, including new developments in surgical approaches with regards to resection techniques, the state of laparoscopic approaches, the growing impact of surgical approaches in the management of recurrent pancreatic cancer, controversies in the management of IMPN as the precursor lesion for PDAC and others – readily at hand. The second edition focuses on advances that will not become dated, and the editors have chosen authors, who are the very best in each area. 000838614 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 16, 2018). 000838614 650_0 $$aPancreas$$xCancer. 000838614 7001_ $$aNeoptolemos, John,$$eeditor. 000838614 7001_ $$aUrrutia, Raul,$$eeditor. 000838614 7001_ $$aAbbruzzese, James L.,$$eeditor. 000838614 7001_ $$aBüchler, Markus,$$d1955-$$eeditor. 000838614 852__ $$bebk 000838614 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4939-7193-0$$zOnline Access$$91397441.1 000838614 909CO $$ooai:library.usi.edu:838614$$pGLOBAL_SET 000838614 980__ $$aEBOOK 000838614 980__ $$aBIB 000838614 982__ $$aEbook 000838614 983__ $$aOnline 000838614 994__ $$a92$$bISE