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Table of Contents
Intro; Preface; Contents; Contributors; About the Editor; 1: Introduction; 1.1 History of Using Black Cumin Seeds for Therapeutic Purposes; 1.2 Components of Nigella sativa Seeds; 1.3 Therapeutic Actions of Thymoquinone; References; 2: Antidiabetic Action of Thymoquinone; 2.1 Diabetes and Glycation; 2.2 Antidiabetic Action of N. sativa Seeds; 2.3 Antidiabetic Action of Thymoquinone (TQ); 2.4 Conclusions; References; 3: Anticancer Action of Thymoquinone; 3.1 Introduction; 3.2 Structure and Function of Thymoquinone; 3.3 Possible Mechanism of Action of Thymoquinone.
3.4 Action of Thymoquinone on Cancer3.5 Thymoquinone Action Against Cancer Through Modulation of Molecular Targets; 3.6 Cell Cycle; 3.7 Enzymes Linked with Cancer Initiation; 3.8 Growth Factors; 3.9 Protein Kinases; 3.10 Antioxidant Enzymes; 3.11 Apoptosis; 3.12 Transcription Factor; 3.13 P53 and PTEN Gene; 3.14 Phase I and Phase II Enzyme; 3.15 Androgen Receptor; 3.16 Telomerase; 3.17 Cellular Components/Microtubules Degradation; 3.18 Human Trial Study Based on Thymoquinone; 3.19 LD 50, Safety and Toxicity Level of Thymoquinone.
3.20 Nano-formulation of Thymoquinone and Its Role in Killing Cancel Cells3.21 Conclusion and Future Prospective; References; 4: Antioxidant and Anti-inflammatory Action of Thymoquinone; 4.1 Oxidative Stress and Antioxidants; 4.2 Antioxidant Action of Thymoquinone; 4.3 Anti-inflammatory Action of Thymoquinone; References; 5: Antimicrobial Action of Thymoquinone; 5.1 Introduction; 5.2 Antibacterial Activity; 5.3 Antiviral Activity; 5.4 Antifungal Activity; 5.5 Conclusions; References; 6: Hepatoprotective Action of Thymoquinone; 6.1 Introduction.
6.2 Protective Action of TQ Under In Vitro Conditions6.3 Protection of Isolated Mice/Rat Hepatocytes by TQ; 6.4 Protective Effect of TQ in Mice/Rat Liver Under In Vivo Conditions; 6.5 Conclusions; References; 7: Anti-epileptic Action of Thymoquinone; 7.1 Epilepsy; 7.2 Anti-epileptic Activity of TQ; 7.3 Role of TQ in Temporal Lobe Epilepsy (TLE); 7.4 Beneficial Interaction of TQ with Known Anti-epileptic Drugs; References; 8: Future Prospects and Conclusions; 8.1 Potential Use of Thymoquinone (TQ) in the Inhibition of Important Cell Signaling Pathways; 8.2 Inhibition of Akt Signaling.
3.4 Action of Thymoquinone on Cancer3.5 Thymoquinone Action Against Cancer Through Modulation of Molecular Targets; 3.6 Cell Cycle; 3.7 Enzymes Linked with Cancer Initiation; 3.8 Growth Factors; 3.9 Protein Kinases; 3.10 Antioxidant Enzymes; 3.11 Apoptosis; 3.12 Transcription Factor; 3.13 P53 and PTEN Gene; 3.14 Phase I and Phase II Enzyme; 3.15 Androgen Receptor; 3.16 Telomerase; 3.17 Cellular Components/Microtubules Degradation; 3.18 Human Trial Study Based on Thymoquinone; 3.19 LD 50, Safety and Toxicity Level of Thymoquinone.
3.20 Nano-formulation of Thymoquinone and Its Role in Killing Cancel Cells3.21 Conclusion and Future Prospective; References; 4: Antioxidant and Anti-inflammatory Action of Thymoquinone; 4.1 Oxidative Stress and Antioxidants; 4.2 Antioxidant Action of Thymoquinone; 4.3 Anti-inflammatory Action of Thymoquinone; References; 5: Antimicrobial Action of Thymoquinone; 5.1 Introduction; 5.2 Antibacterial Activity; 5.3 Antiviral Activity; 5.4 Antifungal Activity; 5.5 Conclusions; References; 6: Hepatoprotective Action of Thymoquinone; 6.1 Introduction.
6.2 Protective Action of TQ Under In Vitro Conditions6.3 Protection of Isolated Mice/Rat Hepatocytes by TQ; 6.4 Protective Effect of TQ in Mice/Rat Liver Under In Vivo Conditions; 6.5 Conclusions; References; 7: Anti-epileptic Action of Thymoquinone; 7.1 Epilepsy; 7.2 Anti-epileptic Activity of TQ; 7.3 Role of TQ in Temporal Lobe Epilepsy (TLE); 7.4 Beneficial Interaction of TQ with Known Anti-epileptic Drugs; References; 8: Future Prospects and Conclusions; 8.1 Potential Use of Thymoquinone (TQ) in the Inhibition of Important Cell Signaling Pathways; 8.2 Inhibition of Akt Signaling.