Linked e-resources
Details
Table of Contents
Intro; Series Editor Foreword; Preface; Contents; Contributors; Chapter 1: Vitamin D Biochemistry and Physiology; Introduction; Vitamin D Production; Vitamin D Metabolism; Transport of Vitamin D Metabolites in the Blood and Their Cellular Uptake; Vitamin D Mechanism of Action; Vitamin D Regulation of Cellular Function; Classic Vitamin D Target Tissues; Nonclassic Vitamin D Target Tissues; Regulation of Proliferation and Differentiation; Regulation of Hormone Secretion; Regulation of the Immune System; References; Chapter 2: Vitamin D and Autoimmune Diseases; Introduction; Vitamin D Deficiency
Systemic Lupus ErythematosusType 1 Diabetes Mellitus; Multiple Sclerosis; Inflammatory Bowel Diseases; Rheumatoid Arthritis; Psoriasis; Other Autoimmune Diseases; Possible Underlying Mechanism; Conclusion; References; Chapter 3: Vitamin D and Infectious Diseases; Why Would Vitamin D Have an Impact on Infectious Diseases?; Historical Aspects; Cod Liver Oil; Light on Mycobacteria; Vitamin D Used in Treatment; Infections Where VD Has Been Hypothesized to Play a Role; Tuberculosis; TB Immunopathology in Relation to Vitamin D-Mediated Immunology
Epidemiological Aspects: Vitamin D Status Among Patients with Active TB InfectionGenetic Aspects: Vitamin D Receptor and Susceptibility Toward TB; Intervention Studies Supplementing Patients with TB with Vitamin D; Other Respiratory Tract Infections; Intervention Studies on Respiratory Tract Infections; Methicillin-Resistant Staphylococcus aureus (MRSA) Carriage in Airways; Sepsis; Observational Studies on Vitamin D and Sepsis; Vitamin D Supplementation Trials; Human Immunodeficiency Virus; Association of Anti-retroviral Treatment (ART) and Vitamin D; Vitamin D Supplementation to HIV Infected
Hepatitis C VirusAssociation of Vitamin D Deficiency with Disease Severity and Sustained Viral Response; Vitamin D Supplementation and Hepatitis; Hepatitis C and HIV Coinfection; Vitamin D as Risk Marker for Infection and Role in Antimicrobial Treatment and Prevention; References; Chapter 4: Vitamin D Hormone Action in the Endocrine Tissue: Implications for Prostate and Breast Carcinoma; Introduction; Vitamin D Metabolism; Synthesis, Degradation, and Roles and Regulation of Key Enzymes; Vitamin D Metabolism in the Prostate
Transcription Regulation by VDR: Domain Structure and Roles for Ligands, DNA Response Elements, and CoregulatorsFunctional Domains of VDR and Inter-domain Allostery; Naturally Occurring VDR Ligands; Calcitriol, Calcidiol, and Secondary Bile Acids; Agonist Actions of Calcitriol and Calcidiol on VDR: Analysis by Molecular Docking; Gene Regulation by VDR: Roles for Coregulators and DNA Response Elements; Interplay of Androgen and Vitamin D in Prostate: Impacts on Cell Proliferation, Vitamin D Metabolism, and the AR Pathway; Effects on Cell Cycle Regulation and E2F1, a Key Cell Cycle Regulator
Systemic Lupus ErythematosusType 1 Diabetes Mellitus; Multiple Sclerosis; Inflammatory Bowel Diseases; Rheumatoid Arthritis; Psoriasis; Other Autoimmune Diseases; Possible Underlying Mechanism; Conclusion; References; Chapter 3: Vitamin D and Infectious Diseases; Why Would Vitamin D Have an Impact on Infectious Diseases?; Historical Aspects; Cod Liver Oil; Light on Mycobacteria; Vitamin D Used in Treatment; Infections Where VD Has Been Hypothesized to Play a Role; Tuberculosis; TB Immunopathology in Relation to Vitamin D-Mediated Immunology
Epidemiological Aspects: Vitamin D Status Among Patients with Active TB InfectionGenetic Aspects: Vitamin D Receptor and Susceptibility Toward TB; Intervention Studies Supplementing Patients with TB with Vitamin D; Other Respiratory Tract Infections; Intervention Studies on Respiratory Tract Infections; Methicillin-Resistant Staphylococcus aureus (MRSA) Carriage in Airways; Sepsis; Observational Studies on Vitamin D and Sepsis; Vitamin D Supplementation Trials; Human Immunodeficiency Virus; Association of Anti-retroviral Treatment (ART) and Vitamin D; Vitamin D Supplementation to HIV Infected
Hepatitis C VirusAssociation of Vitamin D Deficiency with Disease Severity and Sustained Viral Response; Vitamin D Supplementation and Hepatitis; Hepatitis C and HIV Coinfection; Vitamin D as Risk Marker for Infection and Role in Antimicrobial Treatment and Prevention; References; Chapter 4: Vitamin D Hormone Action in the Endocrine Tissue: Implications for Prostate and Breast Carcinoma; Introduction; Vitamin D Metabolism; Synthesis, Degradation, and Roles and Regulation of Key Enzymes; Vitamin D Metabolism in the Prostate
Transcription Regulation by VDR: Domain Structure and Roles for Ligands, DNA Response Elements, and CoregulatorsFunctional Domains of VDR and Inter-domain Allostery; Naturally Occurring VDR Ligands; Calcitriol, Calcidiol, and Secondary Bile Acids; Agonist Actions of Calcitriol and Calcidiol on VDR: Analysis by Molecular Docking; Gene Regulation by VDR: Roles for Coregulators and DNA Response Elements; Interplay of Androgen and Vitamin D in Prostate: Impacts on Cell Proliferation, Vitamin D Metabolism, and the AR Pathway; Effects on Cell Cycle Regulation and E2F1, a Key Cell Cycle Regulator