000838945 000__ 05787cam\a2200517Mi\4500 000838945 001__ 838945 000838945 005__ 20230306144703.0 000838945 006__ m\\\\\o\\d\\\\\\\\ 000838945 007__ cr\un\nnnunnun 000838945 008__ 180502s2018\\\\si\\\\\\o\\\\\000\0\eng\d 000838945 019__ $$a1035302874$$a1035519674$$a1041644598 000838945 020__ $$a9789811051432$$q(electronic book) 000838945 020__ $$a9811051437$$q(electronic book) 000838945 020__ $$z9789811051425 000838945 020__ $$z9811051429 000838945 0247_ $$a10.1007/978-981-10-5143-2$$2doi 000838945 035__ $$aSP(OCoLC)on1034544191 000838945 035__ $$aSP(OCoLC)1034544191$$z(OCoLC)1035302874$$z(OCoLC)1035519674$$z(OCoLC)1041644598 000838945 040__ $$aAZU$$beng$$cAZU$$dGW5XE$$dOCLCO$$dN$T$$dGW5XE$$dN$T$$dEBLCP$$dDKU$$dYDX$$dUAB$$dOCLCF$$dOCLCQ 000838945 049__ $$aISEA 000838945 050_4 $$aRD668.5 000838945 08204 $$a616.99/4347059$$223 000838945 24500 $$aSurgical Treatment of Colorectal Cancer :$$bAsian Perspectives on Optimization and Standardization /$$cedited by Nam Kyu Kim, Kenichi Sugihara, Jin-Tung Liang. 000838945 264_1 $$aSingapore :$$bSpringer Singapore :$$bImprint: Springer,$$c2018. 000838945 300__ $$a1 online resource (xx, 414 pages) :$$billustrations. 000838945 336__ $$atext$$btxt$$2rdacontent 000838945 337__ $$acomputer$$bc$$2rdamedia 000838945 338__ $$aonline resource$$bcr$$2rdacarrier 000838945 347__ $$atext file$$bPDF$$2rda 000838945 5050_ $$aIntro; Preface; Acknowledgments; Contents; List of Editors and Associate Editors; Part I: Essential Basic Considerations in Colorectal Cancer; 1: Epidemiology of Colorectal Cancer in Asia-Pacific Region; 1.1 Trends of Colorectal Cancer Incidence and Mortality; 1.1.1 Temporal Trends; 1.1.2 Geographic Variations; 1.1.3 Survival of Colorectal Cancer Patients; 1.2 Risk Factors; 1.2.1 Smoking; 1.2.2 Alcohol Drinking; 1.2.3 Meat Consumption; 1.2.4 Obesity and Physical Inactivity; 1.2.5 Fruits and Vegetables; 1.2.6 Soy Product and Green Tea Consumption 000838945 5058_ $$a1.2.7 Dairy Product and Whole Grains1.2.8 Migrant Studies; References; 2: A Multidisciplinary Approach for Advanced Colorectal Cancer; 2.1 Definition and Team Composition; 2.2 Increasing Need for Clinical MDTs and a Brief Introduction to Our Experience of a MDT; 2.3 Impact of MDT; 2.3.1 Changes in Decision- Making and Subsequent Treatment Plans; 2.3.2 Increasing Adherence to Treatment Guidelines; 2.3.3 Improvement of Surgical Outcomes; 2.3.4 Impact on Patient Satisfaction and Quality of Life; 2.3.5 Impact on Survival 000838945 5058_ $$a2.3.6 Impact on Research and Evidence-Making Process and Education2.4 Debate on Efficacy of MDT; 2.5 Factors Affecting the Efficacy of MDT Clinics; 2.5.1 Time Pressure and Inadequate Information; 2.5.2 Leadership and Team Culture; 2.5.3 Infrastructures and Decision Support System; 2.5.4 Feedback on MDT Performance; 2.6 Future Perspectives; References; 3: Molecular Basis of Colorectal Cancer: Tumor Biology; 3.1 Introduction; 3.2 Three Molecular Carcinogenesis Pathways and Two Morphologic Multistep Pathways; 3.3 CIN; 3.3.1 Defects in Chromosomal Segregation 000838945 5058_ $$a3.3.2 Centromere Dysfunction3.3.3 Telomere Dysfunction; 3.3.4 Loss of Heterozygosity (LOH); 3.3.5 Deficiencies in DNA Damage Response; 3.3.6 Clinical Implications of CIN; 3.4 MSI; 3.4.1 Clinical Implication of MSI; 3.5 CIMP; 3.5.1 Clinical Implications of CIMP; 3.6 Consensus Molecular Subtypes; References; Part II: Anatomic Considerations in Rectal Cancer Surgery; 4: Anatomical Basis of Rectal Cancer Surgery Focused on Pelvic Fascia; 4.1 Introduction; 4.2 Anatomic Concepts of Toldt Fascia; 4.3 Rectosacral and Waldeyer's Fascia Revisited 000838945 5058_ $$a4.4 Dissection of Denonvilliers' Fascia Implicated in Total Mesorectal Excision4.5 In Conclusion; References; 5: The Lymphatic Spread of the Rectal Cancer; 5.1 Introduction; 5.2 The Pattern of the Lymphatic Drainage According to the Tumor Location; 5.3 Lymph Node Groups; 5.4 Concept of Lymphadenectomy; 5.5 Debated About Lateral Pelvic Lymph Node Dissection (West vs. East); 5.6 Selective Pelvic Lymph Node Dissection After Preoperative Chemoradiotherapy; 5.7 Pathologic Assessment of Rectal Lymph Node; References; 6: Anal Sphincter Complex Preservation; 6.1 Introduction; 6.2 Anatomy 000838945 506__ $$aAccess limited to authorized users. 000838945 520__ $$aThis book presents an Asian perspective on how the treatment of colorectal cancer can be optimized and standardized in ways that take into account technological advances and the trend towards individually tailored therapy. Readers will find careful, well-illustrated descriptions of the standard surgical techniques for rectal cancer and colon cancer that have contributed to recent improvements in 5-year survival rates in the Asia-Pacific region, where the incidence of colorectal cancer has been rising alarmingly due to lifestyle changes. The vital role now being played by minimally invasive laparoscopic and robotic options receives detailed scrutiny. Extent and timing of surgery, patient safety, risk of complications, and unresolved issues are all discussed. Furthermore, the use of surgery within the context of multimodal management including chemotherapy and radiotherapy is explained and an integrated approach for stage IV and recurrent disease is described. The book will serve as a valuable reference for young surgeons who are in training, experienced practitioners who want to enhance their knowledge and skills, and all others who wish to learn about this field. 000838945 650_0 $$aColon (Anatomy)$$xCancer$$xSurgery. 000838945 650_0 $$aRectum$$xCancer$$xSurgery. 000838945 7001_ $$aKim, Nam Kyu,$$eeditor. 000838945 7001_ $$aSugihara, Kenichi,$$eeditor. 000838945 7001_ $$aLiang, Jin-Tung,$$eeditor. 000838945 77608 $$iPrint version:$$z9789811051425 000838945 852__ $$bebk 000838945 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-10-5143-2$$zOnline Access$$91397441.1 000838945 909CO $$ooai:library.usi.edu:838945$$pGLOBAL_SET 000838945 980__ $$aEBOOK 000838945 980__ $$aBIB 000838945 982__ $$aEbook 000838945 983__ $$aOnline 000838945 994__ $$a92$$bISE