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Chapter 2: Pathology of Pheochromocytoma and ParagangliomaIntroduction; Pheochromocytoma; Paraganglioma; Head and Neck Paragangliomas; Sympathetic Paragangliomas; Composite Pheochromocytoma and Composite Paraganglioma; References; Chapter 3: Clinical Features of Pheochromocytoma and Paraganglioma; Overview; Catecholamine Storage and Release from Pheochromocytomas and Paragangliomas; Clinical Manifestations and Pathophysiology; Hypertension; The Paroxysm; Other Manifestations (Table 3.4); Adverse Impact of Drugs and Diagnostic Tests; Direct Release of Catecholamines from the Tumor
Release of Catecholamines from the Augmented Stores in Sympathetic Nerve EndingsInterference with Inactivation of Catecholamines; Features that Warrant Screening for Pheochromocytoma in Hypertensive Patients; Adrenal Incidentalomas; Characteristics of Pheochromocytoma in Familial Syndromes; MEN Syndromes; Von Hippel-Lindau (VHL) Retinal Cerebellar Hemangioblastomatosis; Neurofibromatosis Type 1 (NF1); Paraganglioma (PGL) Syndromes: Succinic Acid Dehydrogenase (SDH) Mutations; Pheochromocytoma of the Urinary Bladder; Extra-adrenal Pheochromocytomas (Paragangliomas)
Characteristics of Bladder PheochromocytomasDifferential Diagnosis; Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma; Catecholamine Production in NB and GNB; Ganglioneuroma; Presentation of Pheochromocytoma: Illustrative Cases; Pheochromocytoma Masquerading as Spells or Seizures; Pheochromocytoma Presenting as Malignant Hypertension; Pheochromocytoma Presenting as Essential Hypertension; Adrenal Incidentaloma, Metastatic Tumor, or Pheochromocytoma?; Noncardiac Pulmonary Edema and Abdominal Catastrophe; Cushing's Syndrome and Pheochromocytoma
Adverse Effects of Mistreatment and Importance of Family ScreeningHigh Stakes of a Missed Diagnosis: Unhappy Ending; References; Chapter 4: Heritable and Syndromic Pheochromocytoma and Paraganglioma; Introduction; Inheritance; Von Hippel-Lindau Disease; Clinical Vignette; Neurofibromatosis Type 1; Multiple Endocrine Neoplasia Type 2; Clinical Vignette; Paraganglioma (PGL) Syndromes; PGL1: SDHD Mutations; PGL2: SDHAF2 Mutations; PGL3: SDHC Mutations; PGL4: SDHB Mutations; Clinical Vignette; PGL5: SDHA Mutations; TMEM127; MAX
Release of Catecholamines from the Augmented Stores in Sympathetic Nerve EndingsInterference with Inactivation of Catecholamines; Features that Warrant Screening for Pheochromocytoma in Hypertensive Patients; Adrenal Incidentalomas; Characteristics of Pheochromocytoma in Familial Syndromes; MEN Syndromes; Von Hippel-Lindau (VHL) Retinal Cerebellar Hemangioblastomatosis; Neurofibromatosis Type 1 (NF1); Paraganglioma (PGL) Syndromes: Succinic Acid Dehydrogenase (SDH) Mutations; Pheochromocytoma of the Urinary Bladder; Extra-adrenal Pheochromocytomas (Paragangliomas)
Characteristics of Bladder PheochromocytomasDifferential Diagnosis; Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma; Catecholamine Production in NB and GNB; Ganglioneuroma; Presentation of Pheochromocytoma: Illustrative Cases; Pheochromocytoma Masquerading as Spells or Seizures; Pheochromocytoma Presenting as Malignant Hypertension; Pheochromocytoma Presenting as Essential Hypertension; Adrenal Incidentaloma, Metastatic Tumor, or Pheochromocytoma?; Noncardiac Pulmonary Edema and Abdominal Catastrophe; Cushing's Syndrome and Pheochromocytoma
Adverse Effects of Mistreatment and Importance of Family ScreeningHigh Stakes of a Missed Diagnosis: Unhappy Ending; References; Chapter 4: Heritable and Syndromic Pheochromocytoma and Paraganglioma; Introduction; Inheritance; Von Hippel-Lindau Disease; Clinical Vignette; Neurofibromatosis Type 1; Multiple Endocrine Neoplasia Type 2; Clinical Vignette; Paraganglioma (PGL) Syndromes; PGL1: SDHD Mutations; PGL2: SDHAF2 Mutations; PGL3: SDHC Mutations; PGL4: SDHB Mutations; Clinical Vignette; PGL5: SDHA Mutations; TMEM127; MAX