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000839250 0247_ $$a10.1007/978-3-319-74470-4$$2doi
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000839250 24500 $$aExosomes, stem cells and microRNA :$$baging, cancer and age related disorders /$$cKarl L. Mettinger, Pranela Rameshwar, Vinod Kumar, editors.
000839250 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2018]
000839250 264_4 $$c©2018
000839250 300__ $$a1 online resource (xiii, 152 pages) :$$bcolor illustrations
000839250 336__ $$atext$$btxt$$2rdacontent
000839250 337__ $$acomputer$$bc$$2rdamedia
000839250 338__ $$aonline resource$$bcr$$2rdacarrier
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000839250 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 1056
000839250 504__ $$aIncludes bibliographical references.
000839250 5050_ $$aPart I. A new stem cell biology: transplantation and baseline, cell cycle and exosomes / Peter Quesenberry, Laura R. Goldberg -- The emerging roles of microRNAs in stem cell aging / Catharine Dietrich, Manish Singh, Nishant Kumar, Shree Ram Singh -- Part II. Treating age-related diseases with somatic stem cells / Robert W. Brooks, Paul D. Robbins -- Targeting miRNA for therapy of juvenile and adult diabetic cardiomyopathy / Shyam Sundar Nandi, Paras Kumar Mishra -- Stem cell therapies for neurodegenerative diseases / Kiminobu Sugaya, Manjusha Vaidya -- Part III. MicroRNAs, regulatory messengers inside and outside cancer cells / Simone Anfossi, Xiao Fu, Rahul Nagvekar, George A. Calin -- Exosomes function in tumor immune microenvironment / Yin Huang, Keli Liu, Qing Li, Yikun Yao, Ying Wang -- EV, microvesicles/microRNAs and stem cells in cancer / Jacob A. Tickner, Derek J. Richard, Kenneth J. O'Byrne -- Human aging and cancer: role of miRNA in tumor microenvironment / Oleta A. Sandiford [and others].
000839250 506__ $$aAccess limited to authorized users.
000839250 520__ $$a"This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries"--Publisher's description.
000839250 588__ $$aDescription based on online resource; title from electronic title page (SpringerLink, viewed May 22, 2018).
000839250 650_0 $$aMicroRNA.
000839250 650_0 $$aStem cells.
000839250 7001_ $$aMettinger, Karl L.$$eeditor.
000839250 7001_ $$aRameshwar, Pranela,$$eeditor.
000839250 7001_ $$aKumar, Vinod$$c(Psychiatrist),$$eeditor.
000839250 77608 $$iPrint version: $$z3319744690$$z9783319744698$$w(OCoLC)1016043891
000839250 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1056.$$x0065-2598
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000839250 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-74470-4$$zOnline Access$$91397441.1
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