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000839347 019__ $$a1037005970$$a1040615303
000839347 020__ $$a9783319732695$$q(electronic book)
000839347 020__ $$a3319732692$$q(electronic book)
000839347 020__ $$z3319732684
000839347 020__ $$z9783319732688
000839347 0247_ $$a10.1007/978-3-319-73269-5$$2doi
000839347 035__ $$aSP(OCoLC)on1036732041
000839347 035__ $$aSP(OCoLC)1036732041$$z(OCoLC)1037005970$$z(OCoLC)1040615303
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000839347 049__ $$aISEA
000839347 050_4 $$aRC600
000839347 08204 $$a616.978$$223
000839347 24500 $$aImmune hematology :$$bdiagnosis and management of autoimmune cytopenias /$$cJenny M. Despotovic, editor.
000839347 260__ $$aCham, Switzerland :$$bSpringer,$$cc2018.
000839347 300__ $$a1 online resource :$$bill.
000839347 336__ $$atext$$btxt$$2rdacontent
000839347 337__ $$acomputer$$bc$$2rdamedia
000839347 338__ $$aonline resource$$bcr$$2rdacarrier
000839347 347__ $$atext file$$bPDF$$2rda
000839347 504__ $$aIncludes bibliographical references and index.
000839347 5050_ $$aIntro; Preface; Contents; Contributors; Part I: Immune Thrombocytopenia (ITP); Chapter 1: Background of Immune Thrombocytopenia; Introduction; Historical Perspective; Terminology; Presentation; Primary ITP and Secondary ITP; Differential Diagnosis; Conclusion; References; Chapter 2: Pathophysiology of Immune Thrombocytopenia; Platelet Autoantibodies; Balance of Platelet Destruction and Production; Abnormal Megakaryocyte Morphology; Antibody Destruction of Megakaryocytes; Inadequate Thrombopoietin Levels; T Cell-Mediated ITP; T Cell-Propagated Autoantibody Production; Helper T Cell Responses
000839347 5058_ $$aRole of Th17 CellsRegulatory T cells; B Cell-Mediated ITP; B-Regulatory Cells; Myeloid-Derived Suppressor Cells; Genetic Studies; Secondary ITP; Helicobacter pylori-Related ITP; CMV-Related ITP; Varicella Zoster-Related ITP; Hepatitis C-Related ITP; HIV-Related ITP; Malignancy-Related ITP; Other Autoimmune Disorders; Evans Syndrome; Autoimmune Lymphoproliferative Syndrome (ALPS); References; Chapter 3: Presentation and Evaluation of Immune Thrombocytopenia; Introduction; Clinical Presentation; History; Physical Examination; Bleeding Assessment; Initial Diagnostic Investigations
000839347 5058_ $$aDiagnostic ApproachAdditional Testing for Suspected ITP; The Role of Bone Marrow Testing; Platelet Antibody Testing; Screening Tests for Associated Conditions; Infectious Triggers for ITP: Hepatitis C, HIV, and H. pylori; Autoimmune Conditions; Immunodeficiencies; Summary; References; Chapter 4: The Treatment of Immune Thrombocytopenia; Introduction; General Treatment Considerations; Who Should Be Treated?; First-Line Management; Corticosteroids; Mechanism of Action; Steroid Treatment Recommendations; Intravenous Immunoglobulin; Mechanism of Action; IVIG Treatment Recommendations
000839347 5058_ $$aAnti-D ImmunoglobulinMechanism of Action; Anti-D Treatment Recommendations; Second-Line Therapy; Splenectomy; Mechanism of Action; Splenectomy Treatment Recommendations; Rituximab; Mechanism of Action; Rituximab Treatment Recommendations; Thrombopoietin Receptor Agonists (TPO-RAs); Mechanism of Action; TPO-RA Adverse Effects; Treatment Recommendations; Use of TPO-RAs in Pediatric ITP; Use of TPO-RAs in Newly Diagnosed ITP; Management of Life-Threatening Bleeding; Other Agents; Antimetabolites; Novel Therapies; References; Part II: Autoimmune Hemolytic Anemia (AIHA)
000839347 5058_ $$aChapter 5: Background, Presentation and Pathophysiology of Autoimmune Hemolytic AnemiaHistory of Immune Hemolysis; Definitions and Classification; Warm AIHA; Pathophysiology; Clinical Features; Cold AIHA (Cold Agglutinin Disease); Pathophysiology; Clinical Features; Paroxysmal Cold Hemoglobinuria; Pathophysiology; Clinical Features; Mixed AIHA; References; Chapter 6: Treatment of Autoimmune Hemolytic Anemia; Introduction; Diagnosis and Classification; Etiology; Frontline Treatment; Blood Transfusions; Corticosteroids; Second-Line Treatments; Rituximab; Splenectomy; Immunosuppressive Therapies
000839347 506__ $$aAccess limited to authorized users.
000839347 520__ $$aThis text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias. Written by experts in each content area, Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias is a valuable resource for clinicians and professionals who treat patients afflicted with autoimmune cytopenias, including primary care providers, hematologist/oncologists, immunologists, among others.
000839347 588__ $$aDescription based on print version record.
000839347 650_0 $$aAutoimmune diseases$$xDiagnosis.
000839347 650_0 $$aImmunology.
000839347 650_0 $$aHematology.
000839347 7001_ $$aDespotovic, Jenny M.
000839347 77608 $$iPrint version:$$z3319732684$$z9783319732688$$w(OCoLC)1013731260
000839347 852__ $$bebk
000839347 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-73269-5$$zOnline Access$$91397441.1
000839347 909CO $$ooai:library.usi.edu:839347$$pGLOBAL_SET
000839347 980__ $$aEBOOK
000839347 980__ $$aBIB
000839347 982__ $$aEbook
000839347 983__ $$aOnline
000839347 994__ $$a92$$bISE