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Title
The hair fibre : proteins, structure and development / Jeffrey E. Plowman, Duane P. Harland, Santanu Deb-Choudhury, editors.
ISBN
9789811081958 (electronic book)
9811081956 (electronic book)
9789811081941
9811081948
Published
Singapore : Springer, 2018.
Language
English
Description
1 online resource.
Other Standard Identifiers
10.1007/978-981-10-8195-8 doi
Call Number
QL942
Dewey Decimal Classification
573.5/8
Summary
Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form. To achieve this the book has been divided into three sections. The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre. The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins. This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed May 29, 2018).
Series
Advances in experimental medicine and biology ; v. 1054.
Available in Other Form
Print version: 9789811081941
Fibre Ultrastructure
The Follicle Cycle in Brief
Diversity of Trichocyte Keratins and Keratin
Evolution of Trichocyte Keratins
Evolution of Trichocyte Keratin Associated Proteins
Structural Hierarchy of Trichocyte Keratin Intermediate Filaments
Trichocyte Keratin-Associated Proteins (KAPs)
Introduction to Hair Development
Environment of the Anagen Follicle
Development of Hair Fibres
Macrofibril Formation
Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins
The Thermodynamics of Trichocyte Keratins
Oxidative Modification of Trichocyte Keratins.
