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Intro; Preface; Contents; 1 Introduction; Abstract; 1.1 Propose of High-solid and Multi-phase Bioprocess; 1.2 Specificity of High-solid and Multi-phase Bioprocess; 1.2.1 The Porous Characteristics and "Solid Effect" of Solid Substrate; 1.2.2 Water-Binding Effect in High-solid and Multi-phase System; 1.2.3 The Rheological Property of High-solid and Multi-phase System; 1.2.4 Transformation Efficiency of High-solid and Multi-phase System; 1.2.5 Intensification of High-solid and Multi-phase Bioprocess and New Bioreactors

1.3 Fundamental Engineering Theories of High-solid and Multi-phase Bioprocess1.4 Development Bottleneck and Tendency of High-solid and Multi-phase Bioprocess; References; 2 Physical-Chemical Properties of Solid Substrates; Abstract; 2.1 Composition and Preparation of Solid Substrates; 2.1.1 Solid Substrates Composition and Recalcitrance; 2.1.2 Solid-Medium Preparation Principles; 2.2 Porous Properties of Solid Substrates; 2.2.1 Cognition on Porous Properties of Solid Substrates; 2.2.2 Correlation Between Substrate Porous Properties and Bioprocess

2.2.3 Enhancement of Seepage Transfer of Porous Solid Substrates for Bioprocess2.3 Water Properties of Solid Substrates; 2.3.1 Cognition on Water States in Solid Substrates; 2.3.2 Correlation Between Substrate Water States and Bioprocess; 2.3.3 Water-Binding Effects of Solid Substrates for Bioprocess; 2.4 Solid Rheology Properties in High-solid and Multi-phase Bioprocess; 2.4.1 Solid Rheology Properties Variation in High-solid and Multi-phase Bioprocess; 2.4.2 Correlation Between Solid Rheology Properties and Bioprocess

2.4.3 From Shearing-Force Stirring of Low Solids to Normal-Force Peristalsis of High SolidsReferences; 3 Intensify Bioreaction Accessibility and Feedstock Refinery Process; Abstract; 3.1 Intensification Principle of Enhancing Substrate Accessibility; 3.1.1 Breakthrough from Biomass Reaction Recalcitrance to Seepage Recalcitrance; 3.1.2 Prevention of the Second Recalcitrance Production; 3.2 Intensification Methods for Enhancing Substrate Accessibility; 3.2.1 Novel Steam Explosion Sterilization Improving Solid-State Fermentation Performance

3.2.1.1 Evaluation of Sterilization Effect by Image Processing3.2.1.2 Determination of Steam Explosion Conditions for Complete Sterilization; 3.2.1.3 Nutrients Contents Before and After Sterilization; 3.2.1.4 FTIR Analysis of Solid Medium Before and After Sterilization; 3.2.1.5 Comparison of Fermentation Performance on Steam Explosion Sterilization and Conventional Thermal Sterilization Medium; 3.2.1.6 Comparison of Production Efficiency Between Steam Explosion Sterilization and Conventional Thermal Sterilization on Large Scale

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