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Intro; Preface; Contents; Contributors; 1: A Complex Case of Major Neurocognitive Disorder: Alzheimer's Disease; 1.1 Case History; 1.2 Genetic Factors Contributing to the Onset of Alzheimer's Disease (AD); 1.3 Genetic Factors Involved in the Early Onset of Alzheimer's Disease; 1.4 Pathological Effects of the Genetic Factors in an Alzheimer's Disease; 1.5 Continuation of the Case; 1.6 Natural History of Alzheimer's Disease?; 1.7 Investigations Used to Establish the Diagnosis?; 1.8 Making a Diagnosis of MND-AD; 1.9 The Cognitive and Behavioral Symptoms in MND-AD
1.10 General Principles of Management of a Patient with Alzheimer's Disease1.11 Effects of MND-AD on the Family Caregivers; 1.12 Legal and Ethical Encounters when Managing a Patient with MND-AD; References; 2: A Complex Case of Delirium: From Theory to Clinical Management; 2.1 Case Presentation: Part I; 2.2 What Is Delirium?; 2.3 FO5 Delirium, Not Induced by Alcohol and Other Psychoactive Substances; 2.4 Prevalence of Delirium; 2.5 Typical Course of Delirium; 2.6 Causes of Delirium; 2.7 Risk Factors for Delirium; 2.8 Diagnosis of Delirium; 2.9 Mimetics of Delirium
2.10 Treatment of Delirium2.11 Non-pharmacologic Strategies in the Management of Delirium; 2.12 Case Presentation: Part II; 2.13 Key Points; References; 3: Geriatric Psychopharmacology: A Complex Case of Psychosis Complicated by Neuroleptic Malignant Syndrome (NMS) and Metabolic Syndrome (MetS); 3.1 Introduction; 3.2 Case Presentation; 3.2.1 Pharmacokinetics; 3.2.2 Pharmacodynamics; 3.2.3 Polypharmacy; 3.3 Neuroleptic Malignant Syndrome (NMS); 3.3.1 Neuroleptic Malignant Syndrome (NMS); 3.3.2 Pathophysiology; 3.3.3 Diagnosis; 3.3.4 Differential Diagnoses; 3.3.5 Risk Factors
3.3.6 Management3.3.7 Case Progression; 3.4 Metabolic Syndrome; 3.4.1 Metabolic Syndrome; 3.4.2 Pathophysiology; 3.4.3 Risk Factors; 3.4.4 Management; 3.4.5 Case Disposition; 3.5 Discussion and Conclusions; 3.5.1 Discussion; 3.5.2 Recommendations; 3.5.2.1 Collaborative Care Management; 3.5.2.2 Criteria and Guidelines; 3.5.2.3 Management of Risk Factors; 3.5.2.4 Drugs of Choice and Dosage; References; 4: A Complex Case of Obsessive-Compulsive Disorder (OCD); 4.1 Case History; 4.2 Psychopharmacological Management of OCD; 4.3 Psychological Treatment of OCD
4.4 Treatment of Refractory OCDReferences; 5: Clinical Conundrum: A Complex Case of Postpartum Depression; 5.1 Objectives; 5.2 Prevalence of PPD; 5.3 Risk Factors for PPD (Fig. 5.1); 5.3.1 Sociodemographic Factors; 5.3.2 Obstetric Factors; 5.3.2.1 Cesarean Section; 5.3.3 Physical and Biological Factors; 5.3.4 Psychological Factors; 5.3.5 Suicide During Pregnancy; 5.3.6 Antenatal Mental Health; 5.3.7 Personality and PPD; 5.3.8 Pharmacological Management; 5.3.9 Suicide in the Postpartum Period; 5.4 A Multidisciplinary Team Approach to Help Ms. V (See Fig. 5.3)
1.10 General Principles of Management of a Patient with Alzheimer's Disease1.11 Effects of MND-AD on the Family Caregivers; 1.12 Legal and Ethical Encounters when Managing a Patient with MND-AD; References; 2: A Complex Case of Delirium: From Theory to Clinical Management; 2.1 Case Presentation: Part I; 2.2 What Is Delirium?; 2.3 FO5 Delirium, Not Induced by Alcohol and Other Psychoactive Substances; 2.4 Prevalence of Delirium; 2.5 Typical Course of Delirium; 2.6 Causes of Delirium; 2.7 Risk Factors for Delirium; 2.8 Diagnosis of Delirium; 2.9 Mimetics of Delirium
2.10 Treatment of Delirium2.11 Non-pharmacologic Strategies in the Management of Delirium; 2.12 Case Presentation: Part II; 2.13 Key Points; References; 3: Geriatric Psychopharmacology: A Complex Case of Psychosis Complicated by Neuroleptic Malignant Syndrome (NMS) and Metabolic Syndrome (MetS); 3.1 Introduction; 3.2 Case Presentation; 3.2.1 Pharmacokinetics; 3.2.2 Pharmacodynamics; 3.2.3 Polypharmacy; 3.3 Neuroleptic Malignant Syndrome (NMS); 3.3.1 Neuroleptic Malignant Syndrome (NMS); 3.3.2 Pathophysiology; 3.3.3 Diagnosis; 3.3.4 Differential Diagnoses; 3.3.5 Risk Factors
3.3.6 Management3.3.7 Case Progression; 3.4 Metabolic Syndrome; 3.4.1 Metabolic Syndrome; 3.4.2 Pathophysiology; 3.4.3 Risk Factors; 3.4.4 Management; 3.4.5 Case Disposition; 3.5 Discussion and Conclusions; 3.5.1 Discussion; 3.5.2 Recommendations; 3.5.2.1 Collaborative Care Management; 3.5.2.2 Criteria and Guidelines; 3.5.2.3 Management of Risk Factors; 3.5.2.4 Drugs of Choice and Dosage; References; 4: A Complex Case of Obsessive-Compulsive Disorder (OCD); 4.1 Case History; 4.2 Psychopharmacological Management of OCD; 4.3 Psychological Treatment of OCD
4.4 Treatment of Refractory OCDReferences; 5: Clinical Conundrum: A Complex Case of Postpartum Depression; 5.1 Objectives; 5.2 Prevalence of PPD; 5.3 Risk Factors for PPD (Fig. 5.1); 5.3.1 Sociodemographic Factors; 5.3.2 Obstetric Factors; 5.3.2.1 Cesarean Section; 5.3.3 Physical and Biological Factors; 5.3.4 Psychological Factors; 5.3.5 Suicide During Pregnancy; 5.3.6 Antenatal Mental Health; 5.3.7 Personality and PPD; 5.3.8 Pharmacological Management; 5.3.9 Suicide in the Postpartum Period; 5.4 A Multidisciplinary Team Approach to Help Ms. V (See Fig. 5.3)