Glucose-sensing receptor in pancreatic beta-cells / Itaru Kojima, editor.

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Glucose-sensing receptor in pancreatic beta-cells / Itaru Kojima, editor.

9789811300028 (electronic book)
981130002X (electronic book)
9811300011
9789811300011

Singapore : Springer Singapore : Imprint: Springer, 2018.

English

1 online resource (v, 71 pages) : illustrations

10.1007/978-981-13-0002-8 doi

QP702.G56

572/.565

Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes. .

Includes bibliographical references.

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