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Table of Contents
1. Cells
Introduction
Basic properties of cells
Two fundamentally different classes of cells
Eukaryotic cells
Model organisms
Cell size
Synthetic biology
Viruses
2. Basics of biochemistry
Covalent bonds
Noncovalent bonds
Hydrophobic and Van Der Waals interactions
Acids, bases, and buffers
The nature of biological molecules
Carbohydrates
Lipids
Proteins
Nucleic acids
3. Metabolism & bioenergetics
Overview of thermodynamics
Enzymes
Metabolism
Oxidation and reduction
Glycolysis
Gluconeogenesis
4. Membranes
Roles of membranes
Membrane structure
Membrane composition
Membrane fluidity
The dynamic nature of the plasma membrane
Movement of substances across membranes
Membrane potentials and nerve impulses
5. Mitochondria and respiration
Introduction
Mitochondria structure and function
Oxidative metabolism
Peroxisomes
6. Chloroplast cells and photosynthesis
Introduction
Chloroplasts
Photosynthesis
Absorption of light
Carbon dioxide fixation
7. Cells and their environment
The extracellular space
Interactions between cells and their environment
Interaction of cells with neighboring cells
Cell walls
8. The cytoplasmic membrane
Introduction
The endoplasmic reticulum
The Golgi complex
Vesicle transport
Lysosomes
Vacuoles
The endocytic pathway
Posttranslational uptake of proteins by peroxisomes,
Mitochondria and chloroplasts
9. Cell motility
Introduction
Microtubules
Intermediate Fi Laments
Microfilaments
10. Basic genetics
Introduction
Chromosomes
The chemical nature of the gene
The stability of the genome
Genome sequencing and the human genome
11. Transcription and translation
Introduction
An overview of transcription
Synthesis and processing of rRNA
Synthesis and processing of tRNA
Synthesis and processing of mRNA
Small regulatory RNAs
Encoding genetic information
Translating genetic information
12. Gene expression in the cell
Introduction
The nucleus
Control of gene expression in bacteria
Control of gene expression in eukaryotes
Transcriptional-level control
Processing level control
Translational level control
Protein degradation
13. DNA
DNA replication
DNA replication in bacteria
DNA replication in eukaryotes
DNA repair
14. Reproduction in cells
The cell cycle
Mitosis
Meiosis
15. Transduction and signaling
The basic elements of cell signaling systems
G-protein coupled receptors (GPCRs)
Protein-tyrosine phosphorylation
Differences in plant and animal receptor signaling
The role of calcium as an intracellular second
Messenger
Convergence, divergence, and crosstalk among different signaling pathways
16. Laboratory techniques
Index.
Introduction
Basic properties of cells
Two fundamentally different classes of cells
Eukaryotic cells
Model organisms
Cell size
Synthetic biology
Viruses
2. Basics of biochemistry
Covalent bonds
Noncovalent bonds
Hydrophobic and Van Der Waals interactions
Acids, bases, and buffers
The nature of biological molecules
Carbohydrates
Lipids
Proteins
Nucleic acids
3. Metabolism & bioenergetics
Overview of thermodynamics
Enzymes
Metabolism
Oxidation and reduction
Glycolysis
Gluconeogenesis
4. Membranes
Roles of membranes
Membrane structure
Membrane composition
Membrane fluidity
The dynamic nature of the plasma membrane
Movement of substances across membranes
Membrane potentials and nerve impulses
5. Mitochondria and respiration
Introduction
Mitochondria structure and function
Oxidative metabolism
Peroxisomes
6. Chloroplast cells and photosynthesis
Introduction
Chloroplasts
Photosynthesis
Absorption of light
Carbon dioxide fixation
7. Cells and their environment
The extracellular space
Interactions between cells and their environment
Interaction of cells with neighboring cells
Cell walls
8. The cytoplasmic membrane
Introduction
The endoplasmic reticulum
The Golgi complex
Vesicle transport
Lysosomes
Vacuoles
The endocytic pathway
Posttranslational uptake of proteins by peroxisomes,
Mitochondria and chloroplasts
9. Cell motility
Introduction
Microtubules
Intermediate Fi Laments
Microfilaments
10. Basic genetics
Introduction
Chromosomes
The chemical nature of the gene
The stability of the genome
Genome sequencing and the human genome
11. Transcription and translation
Introduction
An overview of transcription
Synthesis and processing of rRNA
Synthesis and processing of tRNA
Synthesis and processing of mRNA
Small regulatory RNAs
Encoding genetic information
Translating genetic information
12. Gene expression in the cell
Introduction
The nucleus
Control of gene expression in bacteria
Control of gene expression in eukaryotes
Transcriptional-level control
Processing level control
Translational level control
Protein degradation
13. DNA
DNA replication
DNA replication in bacteria
DNA replication in eukaryotes
DNA repair
14. Reproduction in cells
The cell cycle
Mitosis
Meiosis
15. Transduction and signaling
The basic elements of cell signaling systems
G-protein coupled receptors (GPCRs)
Protein-tyrosine phosphorylation
Differences in plant and animal receptor signaling
The role of calcium as an intracellular second
Messenger
Convergence, divergence, and crosstalk among different signaling pathways
16. Laboratory techniques
Index.