000842331 000__ 03977cam\a2200481\i\4500 000842331 001__ 842331 000842331 005__ 20210515152121.0 000842331 006__ m\\\\\o\\d\\\\\\\\ 000842331 007__ cr\cn\nnnunnun 000842331 008__ 160715t20172017njua\\\\ob\\\\001\0\eng|d 000842331 020__ $$z9781119060680 000842331 020__ $$a9781119060802$$q(electronic book) 000842331 035__ $$a(MiAaPQ)EBC4745624 000842331 035__ $$a(Au-PeEL)EBL4745624 000842331 035__ $$a(CaPaEBR)ebr11300198 000842331 035__ $$a(CaONFJC)MIL978150 000842331 035__ $$a(OCoLC)964410742 000842331 040__ $$aMiAaPQ$$beng$$erda$$epn$$cMiAaPQ$$dMiAaPQ 000842331 050_4 $$aRS431.A64$$bA58 2017 000842331 0820_ $$a615.7/98$$223 000842331 1300_ $$aAntibody-drug conjugates (Olivier) 000842331 24510 $$aAntibody-drug conjugates :$$bfundamentals, drug development, and clinical outcomes to target cancer /$$cedited by Kenneth J. Olivier Jr. and Sara A. Hurvitz. 000842331 264_1 $$aHoboken, New Jersey :$$bJohn Wiley & Sons, Incorporated,$$c[2017] 000842331 264_4 $$c©2017 000842331 300__ $$a1 online resource (566 pages) :$$bcolor illustrations 000842331 336__ $$atext$$2rdacontent 000842331 337__ $$acomputer$$2rdamedia 000842331 338__ $$aonline resource$$2rdacarrier 000842331 504__ $$aIncludes bibliographical references and index. 000842331 5050_ $$aTypical antibody-drug conjugates / John Lambert -- Selecting optimal ADC targets using indication-dependent or indication-independent approaches / Robert Hollingsworth and Jay Harper -- Antibody drug conjugates : an overview of the CMC and characterization process / Janet Wolfe and Phillip Ross -- Linker and conjugation technology and improvements / Riley Ennis and Sourav Sinha -- Formulation and stability / Kouhei Tsumoto, Anthony Young, and Satoshi Ohtake -- QC assay development / Xiao-Hong Chen and Mate Tolnay -- Occupational health and safety aspects of ADCs and their toxic payloads / Robert Sussman and John Farris -- Bioanalytical strategies enabling successful ADC translation / Xiaogang Han, Lindsay King, and Steve Hansel -- Nonclinical pharmacology and mechanistic modeling of antibody drug conjugates in support of human clinical trials / Brian J. Schmidt, Chin Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, and Manish Gupta -- Pharmacokinetics of antibody-drug conjugates / Amrita Kamath -- Path to market approval : regulatory perspective of ADC nonclinical safety assessments / Stacey Ricci and Natalie Simpson -- Antibody drug conjugates : clinical strategies and applications / Heather E. Vezina, Lucy Lee, Brian J. Schmidt, Manish Gupta -- Antibody-drug conjugates (ADCs) in clinical development / Patricia LoRusso and Joseph McLaughlin -- ADCs approved for use : Trastuzumab emtansine (Kadcyla, T-DM1) in patients with previously treated HER2-positive metastatic breast cancer / Gail Lewis Phillips, Sanne de Hass, Sandhya Girish, and Ellie Guardino -- ADCs approved for use : Brentuximab Vedotin / Sven DeVos and Monica Mead -- Radioimmunotherapy / Jeffrey Wong and Savita Dandapani -- Radiolabeled antibody-based imaging in clinical oncology / Bart Hendriks and Daniel Gaddy -- Antibody-drug conjugates : the next evolution in the cure for cancer -- William C. Olson and Amy Q. Han. 000842331 506__ $$aAccess limited to authorized users. 000842331 588__ $$aDescription based on print version record. 000842331 650_0 $$aAntibody-toxin conjugates. 000842331 650_0 $$aMonoclonal antibodies. 000842331 650_0 $$aAntineoplastic agents. 000842331 650_0 $$aTumors$$xTreatment. 000842331 7001_ $$aOlivier, Kenneth J.,$$cJr.,$$d1968-$$eeditor. 000842331 7001_ $$aHurvitz, Sara A.,$$d1970-$$eeditor. 000842331 77608 $$iPrint version:$$aAntibody-drug conjugates (Olivier)$$tAntibody-drug conjugates : fundamentals, drug development, and clinical outcomes to target cancer.$$dHoboken, New Jersey : John Wiley & Sons, Incorporated, [2017]$$z9781119060680$$w(DNLM)101688103 000842331 852__ $$bebk 000842331 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=https://ebookcentral.proquest.com/lib/usiricelib-ebooks/detail.action?docID=4745624$$zOnline Access 000842331 909CO $$ooai:library.usi.edu:842331$$pGLOBAL_SET 000842331 980__ $$aEBOOK 000842331 980__ $$aBIB 000842331 982__ $$aEbook 000842331 983__ $$aOnline