000843588 000__ 02994cam\a2200481Mi\4500 000843588 001__ 843588 000843588 005__ 20230306144900.0 000843588 006__ m\\\\\o\\d\\\\\\\\ 000843588 007__ cr\nn\nnnunnun 000843588 008__ 180614s2018\\\\it\\\\\\o\\\\\000\0\eng\d 000843588 020__ $$a9788876426421$$q(electronic book) 000843588 020__ $$a8876426426$$q(electronic book) 000843588 0247_ $$a10.1007/978-88-7642-642-1$$2doi 000843588 035__ $$aSP(OCoLC)on1040652153 000843588 035__ $$aSP(OCoLC)1040652153 000843588 040__ $$aAZU$$beng$$cAZU$$dOCLCO$$dGW5XE$$dFIE$$dOCLCF$$dUAB 000843588 049__ $$aISEA 000843588 050_4 $$aQH455 000843588 08204 $$a570.285$$223 000843588 1001_ $$aCellerino, Alessandro.$$eauthor. 000843588 24510 $$aTranscriptome Analysis :$$bIntroduction and Examples from the Neurosciences /$$cby Alessandro Cellerino, Michele Sanguanini. 000843588 264_1 $$aPisa :$$bScuola Normale Superiore :$$bImprint: Edizioni della Normale,$$c2018. 000843588 300__ $$a1 online resource (xiv, 188 pages) 000843588 336__ $$atext$$btxt$$2rdacontent 000843588 337__ $$acomputer$$bc$$2rdamedia 000843588 338__ $$aonline resource$$bcr$$2rdacarrier 000843588 347__ $$atext file$$bPDF$$2rda 000843588 4901_ $$aCRM Series ;$$v17 000843588 5050_ $$aPreface -- Introduction: why study transcriptomics? -- 1. Data distribution and visualisation -- 2. Next-generation RNA sequencing -- 3. RNA-seq raw data processing -- 4. Differentially expressed gene detection & analysis -- 5. Unbiased clustering methods -- 6. Knowledge-based clustering methods -- 7. Network analysis -- 8. Mesoscale transcriptome analysis -- 9. Microscale transcriptome analysis -- Bibliography -- Index. 000843588 506__ $$aAccess limited to authorized users. 000843588 520__ $$aThe goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpretation of high-dimensional data is made difficult by the lack of a common language between experimental and data scientists. By combining theory with practical examples of how specific tools were used to obtain novel insights in biology, particularly in the neurosciences, the book intends to teach students how to design, analyse, and extract biological knowledge from transcriptome sequencing experiments. Undergraduate and graduate students in biomedical and quantitative sciences will benefit from this text as well as academics untrained in the subject. 000843588 650_0 $$aBioinformatics. 000843588 650_0 $$aSystems biology. 000843588 650_0 $$aBiomathematics. 000843588 650_0 $$aGenetic transcription. 000843588 7001_ $$aSanguanini, Michele.$$eauthor. 000843588 77608 $$iPrint version: $$z9788876426414 000843588 830_0 $$aConcordia.$$pReihe Monographien ;$$v17. 000843588 852__ $$bebk 000843588 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-88-7642-642-1$$zOnline Access$$91397441.1 000843588 909CO $$ooai:library.usi.edu:843588$$pGLOBAL_SET 000843588 980__ $$aEBOOK 000843588 980__ $$aBIB 000843588 982__ $$aEbook 000843588 983__ $$aOnline 000843588 994__ $$a92$$bISE