Intro; Foreword; Preface; Acknowledgments; Contents; List of Videos; Part I: Fundamental Biostatistics for Translational Research; 1: Introduction to Biostatistics; 1.1 Core Concepts; 1.2 The Scientific Method; 1.2.1 The Research Process; 1.2.1.1 Hypothesis-Driven Research; 1.2.1.2 Errors in Research; 1.2.2 Biostatistics Today; 1.2.2.1 Relevance for the Health Sciences; 1.2.2.2 Research in Translational Healthcare; 1.2.3 Self-Study: Practice Problems; 2: Study Design; 2.1 Core Concepts; 2.2 Conceptual Introduction; 2.3 Diagnostic Studies; 2.3.1 Reliability and Validity

2.3.2 Specificity and Sensitivity2.4 Prognostic Studies; 2.4.1 Observational Design; 2.4.1.1 Cohort Studies; 2.4.1.2 Case-Control Studies; 2.4.1.3 Cross-Sectional Studies; 2.4.2 Experimental Design; 2.4.2.1 Clinical Trials; 2.5 Self-Study: Practice Problems; 3: Methodology; 3.1 Core Concepts; 3.2 Conceptual Introduction; 3.3 Sample vs. Population; 3.3.1 Sampling Methods; 3.4 Measurement; 3.4.1 Instrument Validity; 3.4.2 Instrument Reliability; 3.5 Data Acquisition; 3.5.1 On Data: Quantitative vs. Qualitative; 3.5.2 Variables; 3.5.2.1 Quantitative; 3.5.2.2 Qualitative

3.6 Self-Study: Practice ProblemsRecommended Reading; 4: Descriptive Statistics; 4.1 Core Concepts; 4.2 Conceptual Introduction; 4.3 Tables and Graphs; 4.4 Descriptive Measures; 4.4.1 Measures of Central Tendency; 4.4.2 Measures of Variability; 4.5 Distributions; 4.6 Probability; 4.6.1 Rules of Probability; 4.6.2 Bayesian vs. Frequentist Approach; 4.6.3 Z-Transformation; 4.7 Self-Study: Practice Problems; 5: Inferential Statistics I; 5.1 Core Concepts; 5.2 Conceptual Introduction; 5.3 Principles of Inference and Analysis; 5.3.1 Sampling Distribution

5.3.2 Assumptions of Parametric Statistics5.3.3 Hypotheses; 5.4 Significance; 5.4.1 Level of Significance; 5.4.2 P-Value; 5.4.3 Decision-Making; 5.4.3.1 Errors in Decision-Making; 5.4.3.2 Power Analysis; 5.4.3.3 Elements of Power Analysis; 5.5 Estimation; 5.6 Hypothesis Testing; 5.7 Study Validity; 5.7.1 Internal Validity; 5.7.2 External Validity; 5.8 Self-Study: Practice Problems; 6: Inferential Statistics II; 6.1 Core Concepts; 6.2 Conceptual Introduction; 6.3 Details of Statistical Tests; 6.3.1 Critical Values; 6.3.2 Directional vs. Nondirectional Tests

6.4 Two-Group Comparisons6.4.1 z Test; 6.4.2 t Test Family; 6.4.2.1 One-Sample t Test; 6.4.2.2 Independent Sample t Test; 6.4.2.3 Dependent Sample t Test; 6.5 Multiple Group Comparison; 6.5.1 ANOVA; 6.6 Continuous Data Analysis; 6.6.1 Associations; 6.6.1.1 Correlation; 6.6.2 Predictions; 6.6.2.1 Simple Linear Regression; 6.6.2.2 Multiple Linear Regression; 6.7 Self-Study: Practice Problem; 7: Nonparametric Statistics; 7.1 Core Concepts; 7.2 Conceptual Introduction; 7.2.1 What Is Nonparametric Statistics?; 7.2.2 When Must We Use the Nonparametric Paradigm?