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Intro; Contents; Abstract; 1 The History of Drug Delivery Systems; 1.1 Introduction; 1.2 Early Drug Delivery Systems; 1.3 The First-Generation Drug Delivery Systems; 1.4 The Second-Generation Drug Delivery Systems; 1.5 The Third-Generation Drug Delivery Systems; References; 2 Classification of Drug Delivery Systems; 2.1 Introduction; 2.2 Conventional Drug Delivery Systems; 2.3 Novel Drug Delivery Systems; 2.3.1 Rate-Preprogrammed Drug Delivery Systems; 2.3.2 Activation-Modulated Drug Delivery Systems; 2.3.2.1 Activation-Modulated by Physical Means
2.3.2.2 Activation-Modulated by Chemical Means2.3.2.3 Activation-Modulated by Biochemical Means; 2.3.3 Feedback-Regulated Drug Delivery Systems; 2.3.4 Site-Targeted Drug Delivery System; 2.4 Classification of DDSs Based on Route of Administration; 2.4.1 Oral Delivery; 2.4.2 Buccal/Sublingual Delivery; 2.4.3 Rectal Delivery; 2.4.4 Parenteral Administration: Intravenous, Subcutaneous, and Intramuscular; 2.5 Classification of DDSs Based on Physical Properties of Dosage Forms; 2.6 Classification of DDSs Based on Drug-Loading Mechanism; References; 3 Drug Modification; 3.1 Introduction
3.2 Surface Character3.3 Size, Shape, and Elasticity; References; 4 Controlled Drug Delivery Systems; 4.1 Introduction; 4.2 Drug Release Mechanisms; 4.2.1 pH-Responsive; 4.2.2 Thermo-Responsive; 4.2.3 Reactive Oxygen Species; 4.2.4 Enzyme; 4.2.5 Ultrasound Response; 4.2.6 Magnetic Response; 4.2.7 Light Response; References; 5 Nanotechnology in Drug Delivery Systems; 5.1 Introduction; 5.2 Nanotubes; 5.3 Mesoporous Structures; 5.4 Nanorods; 5.5 Lipids; 5.6 Quantum Dots; References; 6 3D Printing Technologies for Drug Delivery; 6.1 Introduction
6.2 The Effect of 3D Shape and Structure on Nano- and Micro-carrier Properties6.2.1 Effect of Carrier Shape Designing on Drug Delivery Performance in Targeting Certain Organs; 6.2.2 Using 3D Shapes in Order to Target the Desired Tissues; 6.2.3 Effect of the Particle Shape on the Specific Surface Area; 6.2.4 Effect of the Particle Shape on Targeting Specific Cells; 6.3 3D Printing Technology; 6.3.1 Stereolithographic (SLA) 3D Printing; 6.3.2 Powder-Based (PB) 3D Printing; 6.3.3 Selective Laser Sintering (SLS) 3D Printing; 6.3.4 Fused Deposition Modeling (FDM) 3D Printing
2.3.2.2 Activation-Modulated by Chemical Means2.3.2.3 Activation-Modulated by Biochemical Means; 2.3.3 Feedback-Regulated Drug Delivery Systems; 2.3.4 Site-Targeted Drug Delivery System; 2.4 Classification of DDSs Based on Route of Administration; 2.4.1 Oral Delivery; 2.4.2 Buccal/Sublingual Delivery; 2.4.3 Rectal Delivery; 2.4.4 Parenteral Administration: Intravenous, Subcutaneous, and Intramuscular; 2.5 Classification of DDSs Based on Physical Properties of Dosage Forms; 2.6 Classification of DDSs Based on Drug-Loading Mechanism; References; 3 Drug Modification; 3.1 Introduction
3.2 Surface Character3.3 Size, Shape, and Elasticity; References; 4 Controlled Drug Delivery Systems; 4.1 Introduction; 4.2 Drug Release Mechanisms; 4.2.1 pH-Responsive; 4.2.2 Thermo-Responsive; 4.2.3 Reactive Oxygen Species; 4.2.4 Enzyme; 4.2.5 Ultrasound Response; 4.2.6 Magnetic Response; 4.2.7 Light Response; References; 5 Nanotechnology in Drug Delivery Systems; 5.1 Introduction; 5.2 Nanotubes; 5.3 Mesoporous Structures; 5.4 Nanorods; 5.5 Lipids; 5.6 Quantum Dots; References; 6 3D Printing Technologies for Drug Delivery; 6.1 Introduction
6.2 The Effect of 3D Shape and Structure on Nano- and Micro-carrier Properties6.2.1 Effect of Carrier Shape Designing on Drug Delivery Performance in Targeting Certain Organs; 6.2.2 Using 3D Shapes in Order to Target the Desired Tissues; 6.2.3 Effect of the Particle Shape on the Specific Surface Area; 6.2.4 Effect of the Particle Shape on Targeting Specific Cells; 6.3 3D Printing Technology; 6.3.1 Stereolithographic (SLA) 3D Printing; 6.3.2 Powder-Based (PB) 3D Printing; 6.3.3 Selective Laser Sintering (SLS) 3D Printing; 6.3.4 Fused Deposition Modeling (FDM) 3D Printing