000844400 000__ 03412cam\a2200505Mi\4500 000844400 001__ 844400 000844400 005__ 20230306144840.0 000844400 006__ m\\\\\o\\d\\\\\\\\ 000844400 007__ cr\nn\nnnunnun 000844400 008__ 180723s2018\\\\gw\\\\\\o\\\\\000\0\eng\d 000844400 019__ $$a1047541367$$a1047780836$$a1048902503 000844400 020__ $$a9783319658223$$q(electronic book) 000844400 020__ $$a3319658220$$q(electronic book) 000844400 020__ $$z9783319658216 000844400 020__ $$z3319658212 000844400 0247_ $$a10.1007/978-3-319-65822-3$$2doi 000844400 035__ $$aSP(OCoLC)on1046544658 000844400 035__ $$aSP(OCoLC)1046544658$$z(OCoLC)1047541367$$z(OCoLC)1047780836$$z(OCoLC)1048902503 000844400 040__ $$aDKU$$beng$$cDKU$$dN$T$$dYDX$$dGW5XE$$dEBLCP 000844400 049__ $$aISEA 000844400 050_4 $$aRD778.5 000844400 08204 $$a616.7$$223 000844400 24500 $$aCollagenase in Dupuytren Disease /$$cedited by Giorgio Pajardi, Marie A. Badalamente, Lawrence C. Hurst. 000844400 264_1 $$aCham :$$bSpringer International Publishing :$$bImprint: Springer,$$c2018. 000844400 300__ $$a1 online resource (xi, 142 pages) $$billustrations. 000844400 336__ $$atext$$btxt$$2rdacontent 000844400 337__ $$acomputer$$bc$$2rdamedia 000844400 338__ $$aonline resource$$bcr$$2rdacarrier 000844400 347__ $$atext file$$bPDF$$2rda 000844400 5050_ $$a1 Biochemistry and mechanism of action of collagen -- 2 Pre-Clinical evaluation and early clinical trials in USA -- 3 Dupuytren's Disease: topographic anatomy of lesions -- 4 Experimental phase in Europe: protocol and first results -- 5 Preparation, injection and traction procedures (Pearls and Tips & Tricks): technical evolution -- 6 First web space, thumb, and nodules -- 7 Rehabilitation after treatment -- 8 Collagenase today: follow-up studies, recurrence, dosage, drug safety -- 9 American and European Regulations -- 10 Collagenase: future perspectives. . 000844400 506__ $$aAccess limited to authorized users. 000844400 520__ $$aThis book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren's contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren's disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren's disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists. 000844400 650_0 $$aDupuytren's contracture$$xTreatment. 000844400 650_0 $$aMedicine. 000844400 650_0 $$aOrthopedics. 000844400 650_0 $$aRehabilitation. 000844400 650_0 $$aSurgery, Plastic. 000844400 7001_ $$aPajardi, Giorgio.$$eeditor. 000844400 7001_ $$aBadalamente, Marie A.$$eeditor. 000844400 7001_ $$aHurst, Lawrence C.$$eeditor. 000844400 77608 $$iPrint version:$$z9783319658216 000844400 852__ $$bebk 000844400 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-65822-3$$zOnline Access$$91397441.1 000844400 909CO $$ooai:library.usi.edu:844400$$pGLOBAL_SET 000844400 980__ $$aEBOOK 000844400 980__ $$aBIB 000844400 982__ $$aEbook 000844400 983__ $$aOnline 000844400 994__ $$a92$$bISE