Intro; Preface; Introduction; Contents; About the Editors; 1: Esophageal Anatomy; Introduction; Esophageal Anatomy; Vascularization and Lymphatic Drainage; Esophageal Surgical Anatomy; Cervical Esophagus; Thoracic Esophagus; Abdominal Esophagus; Anatomy for Esophageal Replacement; Esophageal Radiologic Anatomy; Endoscopic Ultrasound; Computed Tomography; Magnetic Resonance; References; 2: Esophageal Squamous Cell Cancer: Pathogenesis and Epidemiology; Introduction; Epidemiology; Pathogenesis; Alcohol and Smoking; Genetic Factors; Diet and Environment; Infection

Premalignant/Neoplastic ConditionOther Factors; Prevention; References; 3: Esophageal Adenocarcinoma: Pathogenesis and Epidemiology; Epidemiology; Pathophysiology: From GERD to Barrett's Esophagus; Pathophysiology: From Barrett's Esophagus to Esophageal Adenocarcinoma; References; 4: Staging of Esophageal Cancer: Implications for Therapy; Introduction; Contemporary Esophageal Cancer Staging; Staging Modalities; CT; CT and T Stage; CT and N Stage; CT and M Stage; MRI; MRI and T Stage; MRI and N Stage; MRI and M Stage; PET CT; EUS; EUS and T Stage; EUS and N Stage; Clinical Impact of EUS

EMR/ESDStaging Laparoscopy; References; 5: Endoscopic Therapy for Superficial Esophageal Cancer; Introduction; Adenocarcinoma; Background; Pretreatment Evaluation; Treatment Outcomes; Squamous Cell Carcinoma; Background; Pretreatment Evaluation; Treatment Outcomes; Endoscopic Resection Modalities; Endoscopic Mucosal Resection; Endoscopic Submucosal Dissection; Ablative Therapy; References; 6: Neoadjuvant and Adjuvant Therapy; Introduction; Neoadjuvant Chemotherapy; Pre-operative Chemoradiation; Pre-operative Chemoradiation for Early Stage Disease; Pre-operative Chemoradiation vs. Chemotherapy

Intensification of Combined Modality TherapyDefinitive Chemoradiation; Post-operative Chemoradiation; Post-operative Chemotherapy; References; 7: Restaging After Neoadjuvant Therapy; Introduction; Role of Endoscopy in Restaging; Endoscopic Biopsy; Endoscopic Ultrasound; Role of FDG-PET/CT in Restaging; Characterization of Disease Burden; Treatment Response and Prognosis; PET-Directed Neoadjuvant Therapy; Ongoing Limitations in Restaging; References; 8: Anesthetic Concerns for Esophageal Surgery; Introduction; Preoperative Evaluation; Initial Assessment and Testing; Patient Selection

OptimizationIntraoperative Management; Surgical Approach; Intraoperative Monitoring; Induction and Airway Management; Ventilator Management; Analgesia; Fluid Management; Perfusion of the Esophagogastric Anastomosis; Postoperative Recovery; Complications; Enhanced Recovery Pathway; References; 9: Transhiatal Esophagectomy; Introduction; Surgical Technique; Abdominal Component; Cervical Component; Mediastinal Component; Anastomosis; Postoperative Course; Suggested Readings; 10: Ivor Lewis Esophagectomy; Introduction; Indications; Contraindications; Endoscopic Evaluation; Surgical Technique