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000850679 019__ $$a1052566599$$a1052872521
000850679 020__ $$a9789811307195$$q(electronic book)
000850679 020__ $$a9811307199$$q(electronic book)
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000850679 0247_ $$a10.1007/978-981-13-0719-5$$2doi
000850679 035__ $$aSP(OCoLC)on1052565464
000850679 035__ $$aSP(OCoLC)1052565464$$z(OCoLC)1052566599$$z(OCoLC)1052872521
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000850679 049__ $$aISEA
000850679 050_4 $$aQP623
000850679 08204 $$a572.8/8$$223
000850679 24500 $$aNon-coding RNAs in complex diseases :$$ba bioinformatics perspective /$$cXia Li, Juan Xu, Yun Xiao, Shangwei Ning, Yunpeng Zhang, editors.
000850679 264_1 $$aSingapore :$$bSpringer,$$c2018.
000850679 300__ $$a1 online resource (x, 126 pages) :$$billustrations.
000850679 336__ $$atext$$btxt$$2rdacontent
000850679 337__ $$acomputer$$bc$$2rdamedia
000850679 338__ $$aonline resource$$bcr$$2rdacarrier
000850679 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 1094
000850679 5050_ $$aIntro; Preface; Contents; Contributors; Chapter 1: Non-coding RNA Resources; 1.1 Introduction; 1.2 ncRNA Annotation Resources; 1.2.1 miRBase; 1.2.2 NONCODE; 1.2.3 LNCipedia; 1.2.4 LNCat; 1.3 ncRNA-Associated Disease Resources; 1.3.1 HMDD; 1.3.2 miR2Disease; 1.3.3 LncRNADisease; 1.3.4 Lnc2Cancer; 1.4 ncRNA-Related Variants Resources; 1.4.1 dPORE-miRNA; 1.4.2 miRdSNP; 1.4.3 miRNASNP; 1.4.4 MirSNP; 1.4.5 PolymiRTS; 1.4.6 MicroSNiPer; 1.4.7 lncRNASNP; 1.4.8 LincSNP; 1.5 Other ncRNA Resources; 1.5.1 DIANA-LncBase; 1.5.2 ChIPBase; 1.5.3 LncRNA2Target; 1.6 Perspectives and Conclusion; References
000850679 5058_ $$aChapter 2: Systematic Identification of Non-coding RNAs2.1 Introduction; 2.2 Methods; 2.2.1 Identification of miRNAs; 2.2.2 Identification of lncRNAs; 2.3 Results; 2.3.1 miRNA Transcriptome Detected by Small RNA-seq Annotation; 2.3.2 Re-annotation of Microarray for Revealing lncRNAs; 2.3.3 Summaries of lncRNA Annotation Resources; 2.3.4 Construction of miRNA and lncRNA Expression Profiles in Heart Failure (Based on miRNA-seq and RNA-seq); 2.4 Concluding Remarks; References; Chapter 3: Functional Characterization of Non-coding RNAs Through Genomic Data Fusion; 3.1 Introduction; 3.2 Methods
000850679 5058_ $$a3.2.1 MiRNA Expression Data Sets3.2.2 Identification of Orthologous miRNAs; 3.2.3 Construction of a Conserved miRNA Co-expression Network; 3.2.4 MiRNA Genomic Location, Cluster, Family, TF, Targets and Disease Information; 3.2.5 Gene Expression Data from miRNA Knockout/Transfection Experiments; 3.2.6 Functional Enrichment Analysis; 3.3 Results; 3.3.1 Construction of a Conserved miRNA Co-expression Network; 3.3.2 Functional Relationships Between Conserved Co-expressed miRNA Pairs; 3.3.3 Dysfunction of miRNA Cooperation in Disease; 3.4 Concluding Remarks; References
000850679 5058_ $$aChapter 4: Genomic-Scale Prioritization of Disease-Related Non-coding RNAs4.1 Introduction; 4.2 Expression-Based Technologies; 4.3 Biological Network-Based Technologies; 4.4 Known Disease-ncRNA Association-Based Technologies; 4.5 Integrated Strategy Based Technologies; 4.6 Conclusions; References; Chapter 5: Genome-Wide Mapping of SNPs in Non-coding RNAs; 5.1 Introduction; 5.2 Mapping SNPs in Human miRNA Targets; 5.3 Mapping Disease-Associated SNPs in lncRNAs; 5.4 Identification of SNPs ́Effects on lncRNA Structure; 5.5 Mapping Disease-Associated SNPs in lncRNA TFBSs
000850679 5058_ $$a5.6 Perspectives and ConclusionReferences; 6: Profiling DNA Methylation Patterns of Non-coding RNAs (ncRNAs) in Human Disease; 6.1 Introduction; 6.2 Re-annotation of Data from the Infinium 450 k Array to Construct lncRNA Methylation Profiles; 6.2.1 Probe Mapping; 6.2.2 DNA Methylation Level Evaluating; 6.2.3 LncRNAs Methylation Profiles Constructing and Methylation Pattern Detecting; 6.3 Classifying lncRNA Methylation Patterns in Cancers; 6.3.1 A Strategy for Methylation Pattern Classifying; 6.3.2 Analysis of Repetitive Elements at lncRNA Promoters
000850679 506__ $$aAccess limited to authorized users.
000850679 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 14, 2018).
000850679 650_0 $$aNon-coding RNA.
000850679 650_0 $$aGenetic disorders.
000850679 7001_ $$aLi, Xia,$$eeditor.
000850679 7001_ $$aXu, Juan,$$eeditor.
000850679 7001_ $$aXiao, Yun,$$eeditor.
000850679 7001_ $$aNing, Shangwei,$$eeditor.
000850679 7001_ $$aZhang, Yunpeng,$$eeditor.
000850679 77608 $$iPrint version: $$z9811307180$$z9789811307188$$w(OCoLC)1032282085
000850679 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1094.
000850679 852__ $$bebk
000850679 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-13-0719-5$$zOnline Access$$91397441.1
000850679 909CO $$ooai:library.usi.edu:850679$$pGLOBAL_SET
000850679 980__ $$aEBOOK
000850679 980__ $$aBIB
000850679 982__ $$aEbook
000850679 983__ $$aOnline
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