000851461 000__ 04537cam\a2200493Ii\4500 000851461 001__ 851461 000851461 005__ 20230306145016.0 000851461 006__ m\\\\\o\\d\\\\\\\\ 000851461 007__ cr\cn\nnnunnun 000851461 008__ 181015s2018\\\\sz\\\\\\ob\\\\000\0\eng\d 000851461 019__ $$a1057233895 000851461 020__ $$a9783319954592$$q(electronic book) 000851461 020__ $$a3319954598$$q(electronic book) 000851461 020__ $$z9783319954585 000851461 020__ $$z331995458X 000851461 035__ $$aSP(OCoLC)on1056952077 000851461 035__ $$aSP(OCoLC)1056952077$$z(OCoLC)1057233895 000851461 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dYDX$$dEBLCP$$dUKMGB$$dOCLCF 000851461 049__ $$aISEA 000851461 050_4 $$aTA164 000851461 08204 $$a660.6$$223 000851461 1001_ $$aCarrà, Sergio,$$eauthor. 000851461 24510 $$aStepping Stones to Synthetic Biology /$$cSergio Carrà. 000851461 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2018] 000851461 300__ $$a1 online resource :$$billustrations 000851461 336__ $$atext$$btxt$$2rdacontent 000851461 337__ $$acomputer$$bc$$2rdamedia 000851461 338__ $$aonline resource$$bcr$$2rdacarrier 000851461 4901_ $$aThe Frontiers Collection 000851461 504__ $$aIncludes bibliographical references. 000851461 5050_ $$aIntro; Preface; Contents; Employed Symbols; Mathematical Notation; Physical Constants; Chapter 1: Devils, Ratchets and Biomolecular Motors; 1.1 The Century of the Devils; 1.2 The Unbearable Attractiveness of Irreversibility; 1.3 The Devil Is a Pawl; 1.4 Swimming in Molasses; 1.5 Down in the Bioworld; References; Chapter 2: Entropy and Information; 2.1 Back to Thermodynamics; 2.2 The Statistical Character of Entropy; 2.3 Out of Equilibrium; 2.4 Shaping the World; 2.5 The Role of Information; 2.6 The Physics of Neglecting; References; Chapter 3: A Computer Called the Universe 000851461 5058_ $$a3.1 A Controversial Origin3.2 The Atomic Universe; 3.3 The Molecular Universe; 3.4 The Birth of Chemistry; 3.5 Back to Earth; 3.6 The Computing Universe; References; Chapter 4: Biomolecules, Networks and Bioenergetics: System Approach to Biology; 4.1 A New Paradigm; 4.2 The Molecules of Life; 4.3 Building the Cells; 4.4 Viruses; 4.5 Thermodynamics in Action; 4.6 The Path of Bioenergy; 4.7 Life and Energy; 4.8 Taming the Rates; 4.9 Towards a System Biology; References; Chapter 5: Making Sense of Life; 5.1 An Enlightening Contribution; 5.2 The Nature and Role of Free Energy 000851461 5058_ $$a5.3 The Eighth Day of Creation5.4 A Gentlemenś Club; 5.5 Central Dogma at Work; 5.6 Feedback Control; 5.7 Regulator Gene; 5.8 Final Remark; References; Chapter 6: Complexity and Information: A Metaphor of Natural and Technological Systems; 6.1 Complexity: A Philosophy or a Tool?; 6.2 A World Patterned by Networks; 6.3 The Language of Nature; 6.4 Natural Computers; 6.5 An Abundance of Energy (and Exergy) from the Top; 6.6 The Emerald Planet; 6.7 Eating the Sun; 6.8 Back to the Macroworld; 6.9 A Glance Towards the Future; References; Chapter 7: The Path of Evolution 000851461 5058_ $$a7.1 The Informational Aspect of Evolution7.2 Evolution and Complexity; 7.3 Simulating Evolution; 7.4 Evolution in a Computer; 7.5 Meta-Biological Darwinism; References; Chapter 8: Imitation of Life: The Cell in a Silicon Chip; 8.1 The Chemoton; 8.2 A Challenging Problem; 8.3 Modeling of Metabolic Reaction Systems; 8.4 FBA Approach; 8.5 Exploring the Escherichia coli; 8.6 Whole Cell; References; Chapter 9: Synthetic Biology at Work; 9.1 The Synthetic Approach to Biology; 9.2 Progress in Gene Manipulations; 9.3 Frontier of Genome Engineering: The CRISPR/Cas System; 9.4 Technical Issues 000851461 5058_ $$a9.5 Works in Progress9.6 A Renewed Synthetic Chemistry; 9.7 Metabolic Engineering; 9.8 Towards a Post-petroleum Era?; References; Chapter 10: Why Life?; 10.1 Resurrecting Prometheus; 10.2 The Beginning of Life; 10.3 Ideas and Theories on the Origin of Life; 10.3.1 Protein First; 10.3.2 Nucleic Acids First; 10.3.3 The Chicken or the Egg?; 10.3.4 RNA World; 10.3.5 The Phase Transition Approach to the Emergence of Life; 10.3.6 Back to Thermodynamics; 10.3.7 The Revenge of Energy; 10.3.8 A Merging Point?; 10.4 The First Synthetic Cell; References; Glossary; Sources; General; Titles in This Series 000851461 506__ $$aAccess limited to authorized users. 000851461 588__ $$aOnline resource; title from PDF title page (viewed October 16, 2018). 000851461 650_0 $$aSynthetic biology. 000851461 77608 $$iPrint version: $$z331995458X$$z9783319954585$$w(OCoLC)1039606035 000851461 830_0 $$aFrontiers collection. 000851461 852__ $$bebk 000851461 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-95459-2$$zOnline Access$$91397441.1 000851461 909CO $$ooai:library.usi.edu:851461$$pGLOBAL_SET 000851461 980__ $$aEBOOK 000851461 980__ $$aBIB 000851461 982__ $$aEbook 000851461 983__ $$aOnline 000851461 994__ $$a92$$bISE