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Intro; Preface; References; Contents; Editor and Contributors; Contributors; Abbreviations; 1: Response Mechanisms to Oxidative Stress in Yeast and Filamentous Fungi; 1.1 Introduction; 1.2 Sources of Reactive Oxygen Species; 1.3 Antioxidant Defence and Thiol Redox Homeostasis; 1.4 Transcriptional Regulation of Antioxidant Defence; 1.5 Oxidative Modifications of Cellular Macromolecules; 1.6 Cell Cycle Progression Delay; 1.7 Induction of Cellular Degradation Systems in Response to Oxidative Stress; 1.8 Activation of the Programmed Cell Death Pathway

1.9 Response to Oxidative Stress: Yeast and Other Fungi1.10 Conclusions; References; 2: Response Mechanisms to Chemical and Physical Stresses in Yeast and Filamentous Fungi; 2.1 Introduction; 2.2 Fungal Responses to pH Extremities; 2.2.1 Acidic pH Stress; 2.2.2 Mechanisms of Tolerance to the Acidic pH; 2.2.3 Alkaline pH Stress; 2.2.4 Resistance to Alkaline pH; 2.2.5 Fungal Response Mechanisms to Changes in Ambient pH; 2.2.6 Mechanisms of the Response and Tolerance to Weak Organic Acids (WOAs); 2.2.7 Mechanisms of WOA Toxicity; 2.2.8 Resistance to WOA; 2.2.9 Response Mechanisms to WOA Stress

2.2.10 Response Mechanisms to WOA Stress in Other Yeast and Fungi2.2.11 Other Antispoilage WOAs; 2.2.12 WOA and Programmed Cell Death; 2.3 Low-Temperature Stress; 2.3.1 Harmful Effects of Low-Temperature Stress; 2.3.2 Resistance to Low-Temperature Stress; 2.3.3 Sensor of Low-Temperature Stress; 2.3.4 Response Mechanisms to Low-Temperature Stress; 2.3.5 High Hydrostatic Pressure: An Intriguing Resemblance to Low-Temperature Stress; 2.4 Osmotic Stress; 2.4.1 Resistance to Osmotic Stress; 2.4.2 Response Mechanisms to Osmotic Stress; 2.4.3 Description of the HOG Signaling Pathway

2.4.4 Hypoosmotic Stress2.5 Desiccation Stress; 2.5.1 Resistance to Dehydration; 2.5.2 Response Mechanisms to Dehydration; 2.6 Practical Aspects of Studying Response Mechanisms to Chemical and Physical Stresses; 2.7 Conclusions and Perspectives; References; 3: How Do Yeast and Other Fungi Recognize and Respond to Genome Perturbations?; 3.1 Introduction; 3.2 The DNA Damage Response in Yeast and Other Fungi; 3.2.1 DNA Damage and DNA Damage Signal; 3.2.2 Cellular Response to DSBs; 3.2.3 Cellular Response to Replication Block; 3.2.4 Chromatin Remodeling Facilitates DDR via DNA Movement

3.2.5 DDR/DRR Proteins Act in Repair Foci3.2.5.1 DSB Repair; 3.2.5.2 Excision Repair Pathways; 3.2.6 Stress Adaptation and Recovery; 3.3 Conclusion and Perspectives; References; 4: The Nutrient Stress Response in Yeast; 4.1 Introduction; 4.2 Nutrient Response Pathways; 4.2.1 Carbon Responsive Networks; 4.2.2 Nitrogen-Responsive Networks; 4.3 Response to Nutrient Limitation; 4.3.1 Regulation of Cellular Growth; 4.3.2 Acute Nutrient Stress Response; 4.3.3 Long-Term Nutrient Stress Response: Stationary Phase and Quiescence; 4.3.4 The Relationship Between Stress and Cell Growth; 4.4 Conclusions

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