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Intro; Foreword; Preface; Acknowledgments; Contents; Contributors; 1: MOSS: A Patient-Centered Approach; Background; Historical Approaches; MOSS, A Patient-Centered Approach to Metastatic Disease of the Spine; Medical/Mental Component; Oncologic Component; Stenosis (Ambulatory/Neurologic) Component; Stability Component; Summary; Application of MOSS: Three Case Reports; Case 1; Case 2; Case 3; References; 2: Relative Radiosensitivity of Metastatic Spine Disease; References; 3: Relative Chemo-, Hormonal, and Immunosensitivity; Introduction; Assessing Response to Treatment; Tissue Procurement.
Variability of SensitivityBreast Cancer; Lung Cancer; Prostate Cancer; Renal Cell Carcinoma; Lymphoma; Myeloma; Sarcoma; Bone Antiresorptive Therapy; References; 4: NOMS; NOMS Framework; Neurologic; Oncologic; Radiation; Chemotherapy and Immunotherapy; Mechanical; Systemic; Surgical Considerations; Separation Surgery; Surgical Stabilization; Case Illustrations; Case #1 Fig. 4.3; Case #2 Fig. 4.4; References; 5: Spinal Instability in Metastatic Disease; Introduction; Initial Evaluation; Clinical Evaluation; Radiographic Evaluation; Plain Radiographs; Nuclear Medicine Scans; Computed Tomography.
Magnetic ResonanceClassification Systems; Denis; Taneichi; Asdourian; White and Panjabi; SINS; References; 6: Imaging Metastatic Spinal Disease; Background; Imaging Considerations; Radiography; Computed Tomography; Magnetic Resonance Imaging; Bone Scintigraphy; Positron-Emission Tomography; Approach to Evaluating the Spine; Illustrative Cases in Diagnostic Imaging; Case 1; Case 2; Case 3; Case 4; Case 5; Case 6; Case 7; Case 8; Case 9; References; 7: Management of Metastatic Spinal Cord Compression Without Stereotactic Radiotherapy and Targeted Adjuvant Chemotherapy; Introduction.
Role of Spine Surgery in Metastatic Spinal Cord Compression TreatmentThe Role of Minimally Invasive (MI) Techniques in MESCC; Decision-Making in Case of Metastatic Spinal Cord Compression; Flow Chart for Multidisciplinary Management of Metastases in the Mobile Spine; Experience at Our Institution; Materials and Methods; Results; References; 8: Metastatic Spine Disease: Critical Evaluation of the Current Literature; Introduction; Steroids; Radiotherapy; Stereotactic Radiosurgery; Surgery; Treatment Framework; References; 9: Indications for En Bloc Spondylectomy for Metastatic Spine Disease.
BackgroundIndications; Surgical Considerations; Outcomes; References; 10: Occipitocervical and Upper Cervical Metastatic Spinal Disease; Introduction; Epidemiology; Presentation; Diagnostic Workup; Laboratory Studies; Treatment Strategy; Radiation; Surgery; References; 11: Mid-cervical Metastatic Spinal Disease; Epidemiology; Pathology; Clinical Presentation; Diagnosis; Indications for Surgery; Surgical Approaches; Anterior; Posterior; Combined Anterior and Posterior Approaches; Complication Avoidance; References; 12: Cervicothoracic Metastatic Spine Disease; General Spinal Metastasis.
Variability of SensitivityBreast Cancer; Lung Cancer; Prostate Cancer; Renal Cell Carcinoma; Lymphoma; Myeloma; Sarcoma; Bone Antiresorptive Therapy; References; 4: NOMS; NOMS Framework; Neurologic; Oncologic; Radiation; Chemotherapy and Immunotherapy; Mechanical; Systemic; Surgical Considerations; Separation Surgery; Surgical Stabilization; Case Illustrations; Case #1 Fig. 4.3; Case #2 Fig. 4.4; References; 5: Spinal Instability in Metastatic Disease; Introduction; Initial Evaluation; Clinical Evaluation; Radiographic Evaluation; Plain Radiographs; Nuclear Medicine Scans; Computed Tomography.
Magnetic ResonanceClassification Systems; Denis; Taneichi; Asdourian; White and Panjabi; SINS; References; 6: Imaging Metastatic Spinal Disease; Background; Imaging Considerations; Radiography; Computed Tomography; Magnetic Resonance Imaging; Bone Scintigraphy; Positron-Emission Tomography; Approach to Evaluating the Spine; Illustrative Cases in Diagnostic Imaging; Case 1; Case 2; Case 3; Case 4; Case 5; Case 6; Case 7; Case 8; Case 9; References; 7: Management of Metastatic Spinal Cord Compression Without Stereotactic Radiotherapy and Targeted Adjuvant Chemotherapy; Introduction.
Role of Spine Surgery in Metastatic Spinal Cord Compression TreatmentThe Role of Minimally Invasive (MI) Techniques in MESCC; Decision-Making in Case of Metastatic Spinal Cord Compression; Flow Chart for Multidisciplinary Management of Metastases in the Mobile Spine; Experience at Our Institution; Materials and Methods; Results; References; 8: Metastatic Spine Disease: Critical Evaluation of the Current Literature; Introduction; Steroids; Radiotherapy; Stereotactic Radiosurgery; Surgery; Treatment Framework; References; 9: Indications for En Bloc Spondylectomy for Metastatic Spine Disease.
BackgroundIndications; Surgical Considerations; Outcomes; References; 10: Occipitocervical and Upper Cervical Metastatic Spinal Disease; Introduction; Epidemiology; Presentation; Diagnostic Workup; Laboratory Studies; Treatment Strategy; Radiation; Surgery; References; 11: Mid-cervical Metastatic Spinal Disease; Epidemiology; Pathology; Clinical Presentation; Diagnosis; Indications for Surgery; Surgical Approaches; Anterior; Posterior; Combined Anterior and Posterior Approaches; Complication Avoidance; References; 12: Cervicothoracic Metastatic Spine Disease; General Spinal Metastasis.