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000856144 019__ $$a1041900363$$a1042350506$$a1046545087$$a1047681037$$a1050969944$$a1058866544$$a1066472386
000856144 020__ $$a9783319782058$$q(electronic book)
000856144 020__ $$a3319782053$$q(electronic book)
000856144 020__ $$z9783319782041
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000856144 0247_ $$a10.1007/978-3-319-78205-8$$2doi
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000856144 049__ $$aISEA
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000856144 08204 $$a617.5/22$$223
000856144 24500 $$aTranslational oral health research /$$cJukka H. Meurman, editor.
000856144 264_1 $$aCham, Switzerland :$$bSpringer,$$c2018.
000856144 300__ $$a1 online resource
000856144 336__ $$atext$$btxt$$2rdacontent
000856144 337__ $$acomputer$$bc$$2rdamedia
000856144 338__ $$aonline resource$$bcr$$2rdacarrier
000856144 347__ $$atext file$$bPDF$$2rda
000856144 504__ $$aIncludes bibliographical references and index.
000856144 5050_ $$aIntro; Preface; Contents; 1: Translational Research in the Oral Health Sciences; 1.1 Definition of Translational Research in the Biomedical Sciences; 1.2 What Is Needed to Carry Out Biomedical Translational Research?; 1.2.1 Graduate Student Training; 1.2.2 Publication of Translational Team Science Research; 1.2.3 The Role of the Institution; References; 2: How Cross-Disciplinary Research Has Increased Our Understanding of Oral Mucosal Diseases; 2.1 Introduction; 2.2 What Is Research in Medical and Dental Schools?; 2.3 Multidisciplinary Clinics.
000856144 5058_ $$a2.4 Assessment of Disease Severity and Treatment Responses in Oral Mucosal Disease2.5 Bullous Diseases; 2.6 Orofacial Granulomatosis; 2.7 Sjögren's Syndrome Clinic; 2.8 Clinical Oral Dryness Score (Fig. 2.7); References; 3: Epigenetics and Periodontitis: A Source of Connection to Systemic Diseases; 3.1 Introduction; 3.1.1 Molecular Regulation of the Immune Response; 3.1.2 Epigenetic Modifications of Gene Expression; 3.1.3 Immune Response in Periodontitis and Epigenetic Modifications; 3.1.4 DNA Methylation, Histone Modulation, and Other Gene Alterations; 3.2 Role of MicroRNAs.
000856144 5058_ $$a3.3 Role of Long Noncoding RNAs3.4 Periodontitis, Epigenetic Alterations, and Systemic Diseases; 3.4.1 Obesity; 3.4.2 Cardiovascular Disease; 3.4.3 Rheumatoid Arthritis; 3.4.4 Cancer; 3.5 Concluding Remarks; References; 4: Topic: aMMP-8 Oral Fluid PoC Test; 4.1 Introduction; 4.2 Periodontal Health Versus Periodontal Inflammation and Clinical Measuring; 4.3 Validity, Sensitivity, and Specificity of Neutrophil Collagenase-2 (aMMP-8) System; 4.4 Justification for aMMP-8 Chairside Test in Reproductive Health Parameters.
000856144 5058_ $$a4.5 Effect of Chronic Periodontitis on Erectile Dysfunction and Sperm Count4.6 Association Between Periodontitis and Conception; 4.7 Emerging Racial Differences on Chronic Periodontitis and Pregnancy Outcomes; 4.8 Role of aMMP-8 Chairside Test in Specific Periodontal Health Parameters; References; 5: Composite Biomaterials: From Lab to Clinics; 5.1 Introduction; 5.2 Dental Applications for FRC; 5.3 All Started from Removable Dentures; 5.4 Next Step: Fixed Dental Prostheses; 5.5 Into the Root Canal; 5.6 To Replace Amalgam; 5.7 Into Bone: Surgical Applications for FRC.
000856144 5058_ $$a5.8 Role of Bioactive Glass5.9 The First Clinical Tests; 5.10 Future Aspects; References; 6: Translational Oral Health Research Implants and Bone Regeneration; 6.1 Introduction; 6.2 Surgical Placement Protocols; 6.3 Immediate Implants; 6.4 Early Implants; 6.5 Ridge Preservation; 6.6 Bone Regeneration of Residual Alveolar Ridges; 6.7 Future Technologies; References; 7: A Critical Reason for Conducting Clinical Trials Is that Results with Humans Are Not Necessarily Predictable from Preclinical Studies; 7.1 Introduction; 7.2 Cystic Fibrosis; 7.3 SCID X1.
000856144 506__ $$aAccess limited to authorized users.
000856144 520__ $$aThis book is the first to be devoted to translational research - which aims to expedite the transfer of knowledge gained in the lab to clinical practice - within the field of oral health. It is examined how basic sciences and basic research are providing new methods and materials that will enable clinicians to treat patients more effectively. Readers will gain a translational perspective on a variety of oral conditions and related systemic diseases. Individual chapters are devoted to such topics as dental biomaterials, implants, and tissue engineering. The importance of evidence-based research and the roles and comparative value of preclinical and clinical trials are also highlighted. Knowledge of translational and clinical research is essential in understanding how new inventions and developments are being accomplished, and what regulations and guidelines need to be taken into account when planning studies, and not forgetting the ethical aspects of any research. Translational Oral Health Research is the first book to be devoted entirely to the subject, and it will be of interest to both researchers and practitioners.
000856144 588__ $$aOnline resource; title from PDF title page (viewed June 21, 2018).
000856144 650_0 $$aOral medicine$$xResearch.
000856144 650_0 $$aDentistry$$xResearch.
000856144 7001_ $$aMeurman, Jukka H.,$$eeditor.
000856144 77608 $$iPrint version:$$tTranslational oral health research.$$dCham, Switzerland : Springer, 2018$$z3319782045$$z9783319782041$$w(OCoLC)1024262731
000856144 852__ $$bebk
000856144 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-78205-8$$zOnline Access$$91397441.1
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000856144 980__ $$aBIB
000856144 982__ $$aEbook
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