Intro; Dedication; Preface; Contents; Contributors; 1: Phagocytes; Origin and Development of Phagocytes; Mononuclear Phagocytes; Granulocytes; Recruitment, Chemotaxis, and Priming; Rolling; Priming; Adhesion; Transendothelial Cell Migration; Phagocytosis and Microbicidal Activity; Phagocytosis; Maturation of Phagosomes; Production of Reactive Oxygen Species; Production of Reactive Nitrogen Species; Oxygen-Independent Antimicrobial Systems; Extracellular Traps (ETs); Antigen Presentation; Concluding Comments; References; 2: T Cell Immunity; Introduction; Origin and Development of T Cells.

Immunodeficiency in the Absence of B CellsSummary; References; 4: Complement; The Complement System; Historical Aspects; Evolution of the Complement System; Synthesis, Distribution, and Catabolism of Complement; Activation of Complement; The Classical Pathway; The Lectin Pathway; The Alternative Pathway; C3: The Central Component of Complement; Activation of the Alternative Pathway; The "Tickover" Model; The Properdin-Directed Model; The Terminal Complement Pathway: Assembly of the Membrane Attack Complex; The Intracellular Complement System; Inhibition of Complement Activation.

Fluid-Phase Complement InhibitorsC1 Inhibitor (C1-INH); Factor I; C4b-Binding Protein (C4BP); Factor H (FH) and the FH Family of Proteins; Vitronectin (Vn); Clusterin (Cn); Membrane-Associated Complement Inhibitors; Complement Receptor 1 (CR1; Also Called CD35 or the Immune Adherence Receptor); CD46 (Membrane Cofactor Protein or MCP); CD55 (Decay-Accelerating Factor [DAF]); CD59 (Homologous Restriction Factor 20 (HRF-20), Membrane Attack Complex Inhibitory Factor (MACIF), or Protectin); Complement Receptor of the Immunoglobulin Superfamily (CRIg); Complement Receptors.