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Table of Contents
Intro; Preface; Contents; Contributors; Part I: Male; Chapter 1: TESE for Cryptozoospermia with Normal Sperm DNA Fragmentation; 1.1 Introduction; 1.2 Sperm DNA Damage Effect on Arts; 1.3 Sperm DNA Damage and Testicular Sperm; 1.4 Cryptozoospermia; 1.5 Cryptozoospermia and Sperm Genetic Integrity; 1.6 Cryptozoospermia: Use of Ejaculated vs. Testicular Sperm for ICSI; 1.6.1 Sperm DNA Damage Limitations; 1.6.2 Cryptozoospermia and Testicular Sperm Retrieval (TSR); 1.6.3 Testicular Sperm Retrieval Limitations; 1.7 Conclusions; References.
Chapter 2: The Argument for Varicocele Repair in Nonobstructive Azoospermia2.1 Introduction; 2.2 Return of Sperm to the Ejaculate; 2.3 Pregnancy Achieved Without Sperm Retrieval After Varicocele Repair; 2.4 Sperm Retrieval and ART Outcomes with Testicular Samples; 2.5 Prognostic Factors; 2.6 Cost Analysis; 2.7 Ancillary Indications for Varicocele Repair in NOA: Androgen Deficiency; 2.8 Conclusions; References; Chapter 3: Current and Future Perspectives on Sperm RNAs; 3.1 Introduction; 3.2 Diversity of Paternal Sperm RNAs; 3.3 Functions of Sperm RNA; 3.4 Clinical Potential of Sperm RNAs.
3.5 Sperm RNA as Epigenetic Modifiers3.6 Transgenerational Heritability Through Paternal RNA; 3.7 Conclusions; References; Chapter 4: Male Infertility as a Marker of Future Health; 4.1 Introduction; 4.2 Genetics, Epigenetics, and Environmental Factors; 4.3 Mental Health and Substance Abuse; 4.4 Cardiovascular Health; 4.5 Endocrine Dysfunction; 4.6 Malignancy; 4.7 Conclusions; References; Chapter 5: Fertility Preservation in the Male Adolescent Patient; 5.1 Introduction; 5.2 Barriers to Fertility Preservation; 5.3 Patient and Parent Concerns Regarding Fertility Preservation.
5.4 Semen Characteristics and Utilization Among Oncology Patients5.5 Testicular Cancer and Semen Parameters; 5.6 Treatment Effect on Fertility; 5.6.1 Chemotherapy; 5.6.2 Radiation Therapy; 5.6.3 Surgery: Retroperitoneal Lymph Node Dissection; 5.7 Alternatives to Semen Cryopreservation; 5.7.1 Prepubertal Testicular Tissue Cryopreservation; 5.8 Conclusions; References; Part II: Female; Chapter 6: Advanced Imaging Techniques Used in the Infertile Female; 6.1 Uterine Imaging; 6.1.1 Uterine Anomalies; 6.1.2 Leiomyoma; 6.1.3 Adenomyosis; 6.1.4 Endometrial Polyps; 6.1.5 Uterine Synechiae.
6.2 Fallopian Tube Imaging6.3 Ovarian Imaging; 6.3.1 Infertility Evaluation and Monitoring; 6.3.2 Ovarian Cysts; 6.4 Endometriosis; 6.5 Conclusions: A Practical Approach to Imaging; References; Chapter 7: Treatment of Subclinical Hypothyroidism in the Infertile Female; 7.1 Introduction; 7.2 Subclinical Hypothyroidism and Infertility; 7.3 Subclinical Hypothyroidism and Adverse Pregnancy Outcomes; 7.4 Subclinical Hypothyroidism and Children Developmental Outcomes; 7.5 Thyroid Antibodies and Female Reproduction; 7.6 Who Should Be Screened for Thyroid Disease?; 7.7 Conclusions; References.
Chapter 2: The Argument for Varicocele Repair in Nonobstructive Azoospermia2.1 Introduction; 2.2 Return of Sperm to the Ejaculate; 2.3 Pregnancy Achieved Without Sperm Retrieval After Varicocele Repair; 2.4 Sperm Retrieval and ART Outcomes with Testicular Samples; 2.5 Prognostic Factors; 2.6 Cost Analysis; 2.7 Ancillary Indications for Varicocele Repair in NOA: Androgen Deficiency; 2.8 Conclusions; References; Chapter 3: Current and Future Perspectives on Sperm RNAs; 3.1 Introduction; 3.2 Diversity of Paternal Sperm RNAs; 3.3 Functions of Sperm RNA; 3.4 Clinical Potential of Sperm RNAs.
3.5 Sperm RNA as Epigenetic Modifiers3.6 Transgenerational Heritability Through Paternal RNA; 3.7 Conclusions; References; Chapter 4: Male Infertility as a Marker of Future Health; 4.1 Introduction; 4.2 Genetics, Epigenetics, and Environmental Factors; 4.3 Mental Health and Substance Abuse; 4.4 Cardiovascular Health; 4.5 Endocrine Dysfunction; 4.6 Malignancy; 4.7 Conclusions; References; Chapter 5: Fertility Preservation in the Male Adolescent Patient; 5.1 Introduction; 5.2 Barriers to Fertility Preservation; 5.3 Patient and Parent Concerns Regarding Fertility Preservation.
5.4 Semen Characteristics and Utilization Among Oncology Patients5.5 Testicular Cancer and Semen Parameters; 5.6 Treatment Effect on Fertility; 5.6.1 Chemotherapy; 5.6.2 Radiation Therapy; 5.6.3 Surgery: Retroperitoneal Lymph Node Dissection; 5.7 Alternatives to Semen Cryopreservation; 5.7.1 Prepubertal Testicular Tissue Cryopreservation; 5.8 Conclusions; References; Part II: Female; Chapter 6: Advanced Imaging Techniques Used in the Infertile Female; 6.1 Uterine Imaging; 6.1.1 Uterine Anomalies; 6.1.2 Leiomyoma; 6.1.3 Adenomyosis; 6.1.4 Endometrial Polyps; 6.1.5 Uterine Synechiae.
6.2 Fallopian Tube Imaging6.3 Ovarian Imaging; 6.3.1 Infertility Evaluation and Monitoring; 6.3.2 Ovarian Cysts; 6.4 Endometriosis; 6.5 Conclusions: A Practical Approach to Imaging; References; Chapter 7: Treatment of Subclinical Hypothyroidism in the Infertile Female; 7.1 Introduction; 7.2 Subclinical Hypothyroidism and Infertility; 7.3 Subclinical Hypothyroidism and Adverse Pregnancy Outcomes; 7.4 Subclinical Hypothyroidism and Children Developmental Outcomes; 7.5 Thyroid Antibodies and Female Reproduction; 7.6 Who Should Be Screened for Thyroid Disease?; 7.7 Conclusions; References.