000856187 000__ 06062cam\a2200565Ii\4500 000856187 001__ 856187 000856187 005__ 20230306145121.0 000856187 006__ m\\\\\o\\d\\\\\\\\ 000856187 007__ cr\un\nnnunnun 000856187 008__ 180711s2018\\\\sz\a\\\\ob\\\\001\0\eng\d 000856187 019__ $$a1043840139$$a1046459203$$a1050719293$$a1055342717$$a1059250349 000856187 020__ $$a9783319905259$$q(electronic book) 000856187 020__ $$a3319905252$$q(electronic book) 000856187 020__ $$a3319905236 000856187 020__ $$a9783319905235 000856187 020__ $$z9783319905235 000856187 020__ $$z3319905236 000856187 0247_ $$a10.1007/978-3-319-90525-9$$2doi 000856187 0243_ $$a9783319905235 000856187 035__ $$aSP(OCoLC)on1043830990 000856187 035__ $$aSP(OCoLC)1043830990$$z(OCoLC)1043840139$$z(OCoLC)1046459203$$z(OCoLC)1050719293$$z(OCoLC)1055342717$$z(OCoLC)1059250349 000856187 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dEBLCP$$dYDX$$dDKU$$dOCLCF$$dUPM$$dVT2$$dOCLCQ$$dCNCEN$$dWYU 000856187 049__ $$aISEA 000856187 050_4 $$aRC815.7 000856187 08204 $$a616.24$$223 000856187 24500 $$aReflux aspiration and lung disease /$$cAlyn H. Morice, Peter W. Dettmar, editors. 000856187 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2018] 000856187 300__ $$a1 online resource :$$billustrations 000856187 336__ $$atext$$btxt$$2rdacontent 000856187 337__ $$acomputer$$bc$$2rdamedia 000856187 338__ $$aonline resource$$bcr$$2rdacarrier 000856187 347__ $$atext file$$bPDF$$2rda 000856187 504__ $$aIncludes bibliographical references and index. 000856187 5050_ $$aIntro; Foreword; Preface; Acknowledgement; Abbreviations; Contents; Part I: Pathology; 1: Diagnostic Confusion Through the Ages; Introduction; True Flatulent Asthma; Page X; Page XXVIII; Page 5; Page 6; Page 9; Page 10; Page 23; Page 176; References; 2: An Overview of Gastroesophageal Reflux Disease; Definition and Clinical Manifestations; Epidemiology; Diagnosis; Proton Pump Inhibitor Trial; Upper Gastrointestinal Endoscopy; Indications for First Upper Gastrointestinal Endoscopy; Indications for Follow-Up Upper Gastrointestinal Endoscopy; 24-h Ambulatory pH or pH-Impedance Monitoring. 000856187 5058_ $$aIndications for 24-h Impedance-pH MonitoringWireless pH Monitoring; Oesophageal Manometry; Other Tests; Medical, Endoscopic and Surgical Therapy; Lifestyle Modifications; Medical Therapy; Endoluminal Therapies; Anti-reflux Surgery; Summary of the Therapeutic Approach; Status of Newer Medications; Improved Acid Suppression; Helicobacter pylori and GORD; References; 3: Chemical Composition of Refluxate; Introduction; Overview of Gastric Secretions; Control of Gastric Secretion; The Gastric Microbiome; Refluxate and Other Non-gastric Secretions; Dietary Intake and Reflux; Summary; References. 000856187 5058_ $$a4: Pathological ProcessesPutative Mechanisms for Reflux/Aspiration Leading to Inflammation; Animal Models; Cell Models; Human Studies; Summary; References; 5: Pathophysiology in the Lung; Gastro Oesophageal Reflux and Aspiration Occurs Normally in Humans; Lung Diseases Associated with GOR and Aspiration; Parenchymal Disease (See Also Chap. 16); Airways Disease; COPD; Asthma; Cystic Fibrosis (CF); Non-cystic Fibrosis Bronchiectasis (NCFB); BOS Post Lung Transplantation; The Role of a Mixed Disciplinary Aerodigestive Team Approach; Questions Raised by This Chapter; What Is Normal? 000856187 5058_ $$aThe Importance of the MicrobiomeUnderstanding Therapy; Interrelationships Between Lung and Gastrointestinal Pathophysiology: The Chicken and Egg of Reflux and Aspiration; The Role of Surgical Fundoplication; References; 6: Effect of Reflux on Cough Sensitivity and Bronchial Responsiveness; Introduction; Reflux and Cough Reflex Sensitivity; Reflux and Bronchial Responsiveness; References; Part II: Diagnosis; 7: Questionnaire Diagnosis of Airways Reflux; Introduction; Airway Reflux Questionnaires; Reflux Symptom Index (RSI); Supraesophageal Reflux Questionnaire (SERQ). 000856187 5058_ $$aPharyngeal Reflux Symptom Questionnaire (PRSQ)Hull Airways Reflux Questionnaire (HARQ); Composite Questionnaires; Discussion; References; 8: Pepsin Detection as a Diagnostic Test for Reflux Disease; Introduction; History of Reflux; History of Pepsin; Reflux Diagnostic Tests: Invasive and Non-invasive; Methods; Patient Recruitment; Sample Collection; Pepsin Analysis; Results; Discussion; References; 9: Imaging Reflux; Introduction; X-ray; Nuclear Medicine; Magnetic Resonance Imaging; References; 10: High Resolution Oesophageal Manometry in the Investigation of Unexplained Cough; Introduction. 000856187 506__ $$aAccess limited to authorized users. 000856187 520__ $$aThis book is about the interface between reflux and the respiratory tract. Reflux is an important factor in many different lung diseases. The pathological basis of reflux has recently undergone major changes in our understanding based on improved diagnostic technology. Readers will learn about how reflux impacts on many common lung conditions. Special circumstances such as eosinophilic inflammation in relation to asthma, cough, and eosinophilic bronchitis will be highlighted. Particular attention is also given to previously unrecognised role of non-acid "airway" reflux. Additionally, pharmacological, surgical and behavioural techniques for diagnostic and treatment are explored witin these chapters This book offers a comprehensive overview of various research areas in reflux in relation to airways disease, since currently there is no summary of how the different but overlapping areas impacted by reflux affect the respiratory tract. It will be of great interest to respiratory physicians, otorhinolaryngologists, and gastroenterologists. 000856187 588__ $$aOnline resource; title from PDF title page (viewed July 13, 2018). 000856187 650_0 $$aGastroesophageal reflux. 000856187 650_0 $$aLungs$$xDiseases. 000856187 7001_ $$aMorice, Alyn H.,$$eeditor. 000856187 7001_ $$aDettmar, Peter W.,$$eeditor. 000856187 77608 $$iPrint version:$$tReflux aspiration and lung disease.$$dCham, Switzerland : Springer, [2018]$$z3319905236$$z9783319905235$$w(OCoLC)1029782689 000856187 852__ $$bebk 000856187 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-90525-9$$zOnline Access$$91397441.1 000856187 909CO $$ooai:library.usi.edu:856187$$pGLOBAL_SET 000856187 980__ $$aEBOOK 000856187 980__ $$aBIB 000856187 982__ $$aEbook 000856187 983__ $$aOnline 000856187 994__ $$a92$$bISE