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Intro; Preface; Contents; Contributors; 1: Fundamentals of Cardiac T1 Mapping; T1; T1 Outside of the Heart; T1 in the Heart; Native T1; Late Gadolinium Enhancement; Extracellular Volume Calculation; T1 Mapping Gold Standard; T1 Mapping in the Heart; Look-Locker Techniques: MOLLI and ShMOLLI; Saturation Recovery Techniques: SASHA; T1 Mapping Limitations; Post-Processing; Validation; Recommendations; References; 2: T1 Mapping in Cardiac Hypertrophy; Introduction; Relationship of T1 and ECV to the Pathophysiology of Hypertrophy; Native T1; Extracellular Volume Fraction (ECV).

Intracellular Life-Time of WaterT1 Mapping in Hypertensive Heart Disease; Animal Studies of T1 Mapping in Hypertensive Heart Disease; T1 mapping in Hypertrophic Cardiomyopathy; T1 Mapping in the Evaluation of Hypertrophy in Aortic Stenosis; Using T1 Mapping to Differentiate between Causes of Hypertrophy; Differentiating Hypertensive Heart Disease from HCM; Differentiating Athletic Hypertrophy from HCM; Differentiation of Hypertensive LVH from Infiltrative Cardiomyopathy; T1 Mapping in Right Ventricular Hypertrophy; References; 3: T1 Mapping in Cardiomyopathy from Cancer Treatment.

Cancer and Cardio-oncologyPathophysiology of Cardiomyopathy from Cancer Treatment; Current Imaging Surveillance of LV Function in Cardio-oncology; Left Ventricular Ejection Fraction; Left Ventricular Strain; T1 Mapping in Cardio-oncology; Myocardial Injury; Myocardial Fibrosis; New Challenges in T1 Mapping in Cardio-oncology; Summary; References; 4: Comparison of T1 Mapping by Cardiac MRI to Non-cardiac MRI Methods to Evaluate Cardiac Fibrosis; Introduction; Cardiac MRI (CMR); Novel CMR Approaches; Nuclear Imaging; Echocardiography; Backscatter; Tissue Doppler Imaging (TDI).

Strain and Strain Rate ImagingSpeckle Tracking Echo; Cardiac Computed Tomography (Multidetector CT); References; 5: T1 Mapping in Aortic Stenosis; Epidemiology; Natural History; Clinical Presentation; Pathobiology of Valvular Disease; Pathobiology of LV Remodeling; Myocardial Fibrosis; Investigations; Electrocardiography; Echocardiography; Cardiac Magnetic Resonance; Late Gadolinium Enhancement; T1 Mapping; Native T1; Post-contrast T1 and the Partition Coefficient; Extracellular Volume Fraction; Absolute Extracellular Volume; Barriers to Widespread Adoption; Potential Uses of T1 Mapping.

Future DirectionsReferences; 6: T1 Mapping in Peri-infarct Injury in Ischemic Cardiomyopathy; Ischemic Cardiomyopathy and T1 Mapping; T1 Mapping Techniques in Ischemic Cardiomyopathy; Gadolinium Enhanced Delayed Enhancement; Role of PIR in Predicting Cardiovascular Outcomes in Ischemic Cardiomyopathy; T1 Mapping Using Gadolinium Enhancement; Limitations to Gadolinium Enhancement; T1 Mapping Sequences for Ischemic Cardiomyopathy; SMART1Map; Combination of Intrinsic T1 Versus Contrast Agent-Enhanced T1 Mapping; Native; Gadolinium (Gd); Manganese (Mn); Summary and Future Directions; References.

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