000856280 000__ 04802cam\a2200601Mu\4500 000856280 001__ 856280 000856280 005__ 20230306145127.0 000856280 006__ m\\\\\o\\d\\\\\\\\ 000856280 007__ cr\un\nnnunnun 000856280 008__ 180915s2018\\\\xx\\\\\\ob\\\\000\0\eng\d 000856280 019__ $$a1050611089$$a1055590044 000856280 020__ $$a9783319935065 000856280 020__ $$a3319935062 000856280 020__ $$z9783319935058 000856280 020__ $$z3319935054 000856280 0247_ $$a10.1007/978-3-319-93506-5$$2doi 000856280 035__ $$aSP(OCoLC)on1053820439 000856280 035__ $$aSP(OCoLC)1053820439$$z(OCoLC)1050611089$$z(OCoLC)1055590044 000856280 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dNLE$$dYDX$$dN$T$$dGW5XE$$dUPM$$dOCLCF$$dOCLCQ$$dOCLCO 000856280 049__ $$aISEA 000856280 050_4 $$aQD415-436RS380RS190- 000856280 08204 $$a547$$223 000856280 1001_ $$aKinghorn, A. Douglas. 000856280 24510 $$aProgress in the Chemistry of Organic Natural Products 107. 000856280 260__ $$aCham :$$bSpringer,$$c2018. 000856280 300__ $$a1 online resource (168 pages). 000856280 336__ $$atext$$btxt$$2rdacontent 000856280 337__ $$acomputer$$bc$$2rdamedia 000856280 338__ $$aonline resource$$bcr$$2rdacarrier 000856280 347__ $$atext file$$bPDF$$2rda 000856280 4901_ $$aProgress in the Chemistry of Organic Natural Products Ser. ;$$vv. 107 000856280 504__ $$aIncludes bibliographical references. 000856280 5050_ $$aIntro; Preface; References; Contents; List of Contributors; The Search for Anticancer Agents from Tropical Plants; 1 Introduction; 2 Clinically Used Plant-derived Anticancer Agents and Compounds in Clinical Trials; 2.1 Plant-derived Compounds Used Clinically as Cancer Chemotherapeutic Agents; 2.2 Examples of Derivatives of Plant Secondary Metabolites Undergoing Clinical Trials as Potential Anticancer Agents; 3 Approaches to the Discovery of Cancer Chemotherapeutic Agents from Higher Plants; 3.1 Development of Plant Collection Agreements Inclusive of Equitable Benefit Sharing. 000856280 5058_ $$a3.2 Logistics of Conducting Plant Collections in Tropical Countries3.2.1 Countries of Origin for Tropical Plant Samples Investigated in Two Research Projects Directed Toward the Discovery of Ne ... ; 3.2.2 Selection of Plants for Collection; 3.2.3 Logistics of Plant Collection Expeditions; 3.2.4 The Conservation Challenge; 3.3 Documentation Involved in Conducting Plant Collections in Tropical Countries; 3.3.1 Plant Samples and Their Herbarium Vouchers; 3.3.2 Field Notebook; 3.3.3 Field Label Data. 000856280 5058_ $$a3.4 Processing of Collected Materials and Considerations Concerning the Export and Import of Plant Materials3.4.1 Processing of Collected Plant Samples; 3.4.2 Processing of Voucher Herbarium Specimens; 3.4.3 Exporting and Importing Collected Plant Materials; 3.5 Specific Phytochemical Considerations; 3.6 Biological Testing of Initial Extracts, Chromatographic Fractions, and Purified Constituents and Their Analogs; 4 Examples of Lead Bioactive Compounds Obtained from Tropical Plants; 4.1 Betulinic Acid; 4.2 Pervilleines A-C and F; 4.3 Phyllanthusmins C and D; 4.4 Silvestrol. 000856280 5058_ $$a4.4.1 Backgound Phytochemical Studies on Aglaia Species (Meliaceae)4.4.2 Isolation of Silvestrol and Structurally Related Dioxanyl Ring-Containing Compounds from Aglaia Species; 4.4.3 Chemical Synthesis Methods for Silvestrol and Related Dioxanyl Ring-Containing Compounds; 4.4.4 Biological Testing and Mechanism of Action Evaluation of Silvestrol; 5 Conclusions; References; An Update of Erythrinan Alkaloids and Their Pharmacological Activities; 1 Introduction; 2 An Update of the Erythrinan Alkaloids; 2.1 D-oxa or Lactone Erythrinan Alkaloids. 000856280 5058_ $$a2.2 Conjugate (Hydrolyzable) Dimeric Erythrinan Alkaloids2.3 True Dimeric Erythrinan Alkaloids; 2.4 Trimeric Erythrinan Alkaloids; 3 Pharmacological Properties of Erythrinan Alkaloids; 3.1 Central Nervous System and Related Activities; 3.2 Antioxidant Activities; 3.3 Anti-inflammatory and Related Activities; 3.4 Antimicrobial Activities; 3.5 Antiprotozoal Activities; 3.6 Antifeedant and Insecticidal Activities; 3.7 Cytotoxicity and Other Activities Related to Cancer; 4 Synthesis Aspects; 5 Conclusions; References. 000856280 506__ $$aAccess limited to authorized users. 000856280 588__ $$aDescripition based on print version record. 000856280 650_0 $$aChemistry, Organic. 000856280 650_0 $$aPharmaceutical chemistry. 000856280 650_0 $$aClinical biochemistry. 000856280 7001_ $$aFalk, Heinz. 000856280 7001_ $$aGibbons, Simon. 000856280 7001_ $$aKobayashi, Junichi. 000856280 7001_ $$aAsakawa, Yoshinori. 000856280 7001_ $$aLiu, Ji-Kai. 000856280 77608 $$iPrint version:$$aKinghorn, A. Douglas.$$tProgress in the Chemistry of Organic Natural Products 107.$$dCham : Springer, ©2018$$z9783319935058 000856280 830_0 $$aProgress in the Chemistry of Organic Natural Products Ser. 000856280 852__ $$bebk 000856280 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-93506-5$$zOnline Access$$91397441.1 000856280 909CO $$ooai:library.usi.edu:856280$$pGLOBAL_SET 000856280 980__ $$aEBOOK 000856280 980__ $$aBIB 000856280 982__ $$aEbook 000856280 983__ $$aOnline 000856280 994__ $$a92$$bISE