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Intro; Foreword; Series Preface; Preface; Contents; Contributors; 1: The Professional Responsibility Model of Ethics in Obstetrics and Gynecology; 1.1 Introduction; 1.2 The Role of Professional Virtues in the Professional Responsibility Model of Ethics in Obstetrics and Gynecology; 1.3 Managing Threats to Professionally Responsible Reproductive Medical Care; 1.3.1 Stage 1: Cynicism; 1.3.2 Stage 2: Wonderland; 1.3.3 Stage 3: Kafkaesque; References; 2: Human Reproduction: From State of the Art to Future Developments "Endometriosis Therapeutic Approaches"; 2.1 Introduction.
2.2 Therapeutic Strategies2.3 Material and Methods (Part I); 2.3.1 Patients; 2.3.2 Exclusion Criteria; 2.3.3 Tissue Samples; 2.3.4 Interventions; 2.3.5 Maine Outcome Measures; 2.3.6 Statistical Evaluation and IRB Approval; 2.3.7 Results (Part I) for Extend of Endometriosis, Fertility, and Pain; 2.4 Material and Methods and Results (Part II); 2.4.1 Endometriosis and Obstetrical Outcome; 2.4.2 Discussion; 2.4.2.1 General Remarks; 2.4.2.2 Three-Step Therapy of Endometriosis; 2.4.2.3 The Influence of Endometriosis on Obstetrical Outcome; 2.5 Conclusions.
2.5.1 The Three-Step Therapy2.5.2 Endometriosis and Obstetrical Outcome; References; 3: The Genetics of Polycystic Ovary Syndrome: From Genome-Wide Association to Molecular Mechanisms; 3.1 Hyperandrogenemia and Polycystic Ovary Syndrome (PCOS); 3.2 The Phenotype of Human Theca Cells from Normal and PCOS Ovaries; 3.3 The Genetics of PCOS; 3.4 DENND1A: A Reasonable Starting Point for Dissection of the Genetics of PCOS; 3.5 What Is the Mechanism for DENND1A.V2 Overexpression in PCOS Theca Cells?; 3.6 A PCOS Genetic Network Incorporating DENND1A; References.
4: Psychosomatic Aspects of Infertility4.1 Introduction; 4.2 Informational Medicine; 4.3 Feedback Information; 4.4 Biocybernetic Conquest of Human Diseases; 4.5 Carcinogenesis According to the Model of Cervical Cancer; 4.6 Causal ACTH Therapy of Recurrent Abortions and Premature Deliveries; 4.7 Individual Date of Human Birth; References; 5: Thyroid Diseases and Female Infertility; 5.1 Introduction; 5.2 Epidemiology of Thyroid Diseases; 5.3 Physiological Effects of Thyroid Hormones on the Female Reproductive System: Molecular Basis and Mechanism of Action.
5.4 Effects on Ovarian Follicles5.5 Effects on the Endometrium; 5.6 Effects on Fertilization; 5.7 Effects on Implantation and Placentation; 5.8 Menstrual Abnormalities in Thyroid Dysfunction; 5.9 Fertility in Women with Thyroid Dysfunction; 5.10 Autoimmune Thyroid Disease AITD and Female Infertility; 5.11 Recommendations and Guidelines for Women with Infertility and Thyroid Diseases/AITD; References; 6: Fertility and Longevity; References; 7: Improving IVF Results: How Far Can We Tamper with Human Biology?; 7.1 Introduction; 7.2 How to Decrease the "Embryo Wastage" Rates.
2.2 Therapeutic Strategies2.3 Material and Methods (Part I); 2.3.1 Patients; 2.3.2 Exclusion Criteria; 2.3.3 Tissue Samples; 2.3.4 Interventions; 2.3.5 Maine Outcome Measures; 2.3.6 Statistical Evaluation and IRB Approval; 2.3.7 Results (Part I) for Extend of Endometriosis, Fertility, and Pain; 2.4 Material and Methods and Results (Part II); 2.4.1 Endometriosis and Obstetrical Outcome; 2.4.2 Discussion; 2.4.2.1 General Remarks; 2.4.2.2 Three-Step Therapy of Endometriosis; 2.4.2.3 The Influence of Endometriosis on Obstetrical Outcome; 2.5 Conclusions.
2.5.1 The Three-Step Therapy2.5.2 Endometriosis and Obstetrical Outcome; References; 3: The Genetics of Polycystic Ovary Syndrome: From Genome-Wide Association to Molecular Mechanisms; 3.1 Hyperandrogenemia and Polycystic Ovary Syndrome (PCOS); 3.2 The Phenotype of Human Theca Cells from Normal and PCOS Ovaries; 3.3 The Genetics of PCOS; 3.4 DENND1A: A Reasonable Starting Point for Dissection of the Genetics of PCOS; 3.5 What Is the Mechanism for DENND1A.V2 Overexpression in PCOS Theca Cells?; 3.6 A PCOS Genetic Network Incorporating DENND1A; References.
4: Psychosomatic Aspects of Infertility4.1 Introduction; 4.2 Informational Medicine; 4.3 Feedback Information; 4.4 Biocybernetic Conquest of Human Diseases; 4.5 Carcinogenesis According to the Model of Cervical Cancer; 4.6 Causal ACTH Therapy of Recurrent Abortions and Premature Deliveries; 4.7 Individual Date of Human Birth; References; 5: Thyroid Diseases and Female Infertility; 5.1 Introduction; 5.2 Epidemiology of Thyroid Diseases; 5.3 Physiological Effects of Thyroid Hormones on the Female Reproductive System: Molecular Basis and Mechanism of Action.
5.4 Effects on Ovarian Follicles5.5 Effects on the Endometrium; 5.6 Effects on Fertilization; 5.7 Effects on Implantation and Placentation; 5.8 Menstrual Abnormalities in Thyroid Dysfunction; 5.9 Fertility in Women with Thyroid Dysfunction; 5.10 Autoimmune Thyroid Disease AITD and Female Infertility; 5.11 Recommendations and Guidelines for Women with Infertility and Thyroid Diseases/AITD; References; 6: Fertility and Longevity; References; 7: Improving IVF Results: How Far Can We Tamper with Human Biology?; 7.1 Introduction; 7.2 How to Decrease the "Embryo Wastage" Rates.