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Intro; Foreword; Preface to the Series; Preface; Contents; 1 Ocimum as a Promising Commercial Crop; Abstract; 1.1 Cultivation Technology; 1.2 Common Varieties; 1.3 Soil and Climate; 1.4 Land Preparation; 1.5 Propagation; 1.5.1 Raising of Nursery; 1.5.2 Transplanting; 1.5.3 Direct Sowing; 1.5.4 Irrigation; 1.6 Interculture and Weeding; 1.7 Manures and Fertilizers; 1.8 Pest and Diseases; 1.9 Crop Rotation; 1.10 Harvesting; 1.11 Distillation and Oil Yield; 1.12 Uses of Basil Oil; References; 2 Ocimum Species: A Longevity Elixir; Abstract; 2.1 Aging; 2.2 Theory of Aging
2.3 C. elegans as a Model for Antiaging Studies2.4 Medicinal Plants and Aging; 2.5 Ocimum spp; 2.6 Phytoconstituents of Ocimum spp; 2.7 Ocimum sps: The Elixir of Life; References; 3 Ocimum: The Holy Basil Against Cardiac Anomalies; Abstract; 3.1 Introduction; 3.2 Types of Cardiovascular Diseases; 3.2.1 Hypertension; 3.2.2 Aortic Aneurysm/Abdominal Aortic Aneurysm; 3.2.3 Acute Coronary Syndrome; 3.2.4 Angina Pectoris; 3.2.5 Atherosclerosis; 3.2.6 Coronary Heart Disease (CHD)/Coronary Artery Disease (CAD); 3.2.7 Heart Attack/Acute Myocardial Infarction (AMI); 3.2.8 Congestive Heart Failure
3.2.9 Ischemic Heart Disease (IHD)3.2.10 Ischemic Stroke; 3.3 Plants as a Medicine; 3.3.1 Ocimum (Tulsi); 3.3.2 Systematics of Tulsi; 3.3.3 Phytochemical Constituents; 3.3.4 Antihypertensive Properties; 3.3.5 Effect on Ischemia; 3.3.6 Effect on Pulmonary Hypertension; 3.3.7 Lipid-Lowering Properties of Ocimum; 3.3.8 Antiplatelet Aggregation Activity; 3.3.9 Antioxidant and Antidiabetic Properties; 3.4 Summary; References; 4 Evolutionary Analysis of a Few Protein Superfamilies in Ocimum tenuiflorum; Abstract; 4.1 Introduction; 4.1.1 Biosynthesis of Terpenoids; 4.1.2 Terpene Synthases
4.1.3 Cytochrome P4504.1.4 Rhomboid Proteases; 4.2 Materials and Methods; 4.2.1 Sequence Search Methodology for Collecting TPS and CYP450 in the Ocimum tenuiflorum (Ote) Proteome; 4.2.2 Structural Alignment to Compare the Functional Important Residues; 4.2.3 Phylogenetic Analysis of TPS and CYP450; 4.2.4 Identification of Rhomboid Proteases in the Ote Proteome; 4.2.5 Identification of Transmembrane Helices and Subcellular Locations of the Rhomboid Proteins; 4.2.6 Multiple Sequence Alignment, Phylogeny and Identification of Variants in Functionally Important Residues
4.2.7 Prediction of Domain Architecture4.3 Results and Discussion; 4.3.1 Sequence and Structure-Based Analysis of Newly Identified Ote (TPS); 4.3.2 Sequence and Structure Analysis of CYP450; 4.3.3 Domain Architecture Analysis of Ote Rhomboid Hits; 4.3.4 Predicting the Cellular Localization, Function, and TM-Helices of Ote Rhomboid Hits; 4.3.5 Alignment to Identify Functionally Important Residues; 4.3.6 Phylogeny and Orthology with Other Plant Hits; 4.3.6.1 Class I-All the Functional Residues Are Conserved; 4.3.6.2 Class II-Only GXSX Conserved; 4.3.6.3 Class III-I Rhom-like Class
2.3 C. elegans as a Model for Antiaging Studies2.4 Medicinal Plants and Aging; 2.5 Ocimum spp; 2.6 Phytoconstituents of Ocimum spp; 2.7 Ocimum sps: The Elixir of Life; References; 3 Ocimum: The Holy Basil Against Cardiac Anomalies; Abstract; 3.1 Introduction; 3.2 Types of Cardiovascular Diseases; 3.2.1 Hypertension; 3.2.2 Aortic Aneurysm/Abdominal Aortic Aneurysm; 3.2.3 Acute Coronary Syndrome; 3.2.4 Angina Pectoris; 3.2.5 Atherosclerosis; 3.2.6 Coronary Heart Disease (CHD)/Coronary Artery Disease (CAD); 3.2.7 Heart Attack/Acute Myocardial Infarction (AMI); 3.2.8 Congestive Heart Failure
3.2.9 Ischemic Heart Disease (IHD)3.2.10 Ischemic Stroke; 3.3 Plants as a Medicine; 3.3.1 Ocimum (Tulsi); 3.3.2 Systematics of Tulsi; 3.3.3 Phytochemical Constituents; 3.3.4 Antihypertensive Properties; 3.3.5 Effect on Ischemia; 3.3.6 Effect on Pulmonary Hypertension; 3.3.7 Lipid-Lowering Properties of Ocimum; 3.3.8 Antiplatelet Aggregation Activity; 3.3.9 Antioxidant and Antidiabetic Properties; 3.4 Summary; References; 4 Evolutionary Analysis of a Few Protein Superfamilies in Ocimum tenuiflorum; Abstract; 4.1 Introduction; 4.1.1 Biosynthesis of Terpenoids; 4.1.2 Terpene Synthases
4.1.3 Cytochrome P4504.1.4 Rhomboid Proteases; 4.2 Materials and Methods; 4.2.1 Sequence Search Methodology for Collecting TPS and CYP450 in the Ocimum tenuiflorum (Ote) Proteome; 4.2.2 Structural Alignment to Compare the Functional Important Residues; 4.2.3 Phylogenetic Analysis of TPS and CYP450; 4.2.4 Identification of Rhomboid Proteases in the Ote Proteome; 4.2.5 Identification of Transmembrane Helices and Subcellular Locations of the Rhomboid Proteins; 4.2.6 Multiple Sequence Alignment, Phylogeny and Identification of Variants in Functionally Important Residues
4.2.7 Prediction of Domain Architecture4.3 Results and Discussion; 4.3.1 Sequence and Structure-Based Analysis of Newly Identified Ote (TPS); 4.3.2 Sequence and Structure Analysis of CYP450; 4.3.3 Domain Architecture Analysis of Ote Rhomboid Hits; 4.3.4 Predicting the Cellular Localization, Function, and TM-Helices of Ote Rhomboid Hits; 4.3.5 Alignment to Identify Functionally Important Residues; 4.3.6 Phylogeny and Orthology with Other Plant Hits; 4.3.6.1 Class I-All the Functional Residues Are Conserved; 4.3.6.2 Class II-Only GXSX Conserved; 4.3.6.3 Class III-I Rhom-like Class