000856318 000__ 04056cam\a2200493Ii\4500 000856318 001__ 856318 000856318 005__ 20230306145129.0 000856318 006__ m\\\\\o\\d\\\\\\\\ 000856318 007__ cr\un\nnnunnun 000856318 008__ 181016s2018\\\\sz\\\\\\ob\\\\001\0\eng\d 000856318 019__ $$a1057377241 000856318 020__ $$a9783319690780$$q(electronic book) 000856318 020__ $$a3319690787$$q(electronic book) 000856318 020__ $$z9783319690773 000856318 020__ $$z3319690779 000856318 035__ $$aSP(OCoLC)on1057018520 000856318 035__ $$aSP(OCoLC)1057018520$$z(OCoLC)1057377241 000856318 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dEBLCP$$dYDX$$dUKMGB$$dOCLCF 000856318 049__ $$aISEA 000856318 050_4 $$aQR13 000856318 08204 $$a579.138$$223 000856318 24500 $$aMolecular mechanisms of microbial evolution /$$cPabulo H. Rampelotto, editor. 000856318 264_1 $$aCham, Switzerland :$$bSpringer,$$c2018. 000856318 300__ $$a1 online resource. 000856318 336__ $$atext$$btxt$$2rdacontent 000856318 337__ $$acomputer$$bc$$2rdamedia 000856318 338__ $$aonline resource$$bcr$$2rdacarrier 000856318 4901_ $$aGrand Challenges in Biology and Biotechnology 000856318 504__ $$aIncludes bibliographical references and index. 000856318 5050_ $$aIntro; Foreword; Preface; Contents; About the Editor; Chapter 1: The Relevance and Challenges of Studying Microbial Evolution; 1 Introduction; 2 Why Understanding Microbial Evolution Is Important; 2.1 Major Events in Lifeś History Was, and Continuous to Be, Influenced by Microbes; 2.1.1 How the Earthś Atmosphere Got Oxygen; 2.1.2 Microbes May Have Caused Earthś Biggest Mass Extinction; 2.1.3 Microbes Control Critical Biogeochemical Processes; 2.1.4 Climate Change and Microbial Evolution; 2.2 Models to Understand General Principles of Evolution; 2.3 Animal Origins and Evolution 000856318 5058_ $$a2.4 Microbes and Humans2.5 Pathogen Evolution; 2.6 Microbial Evolution Can Be Used to Solve Global Problems; 3 Challenges in the Study of Microbial Evolution; References; Chapter 2: Mayr Versus Woese: Akaryotes and Eukaryotes; 1 Introduction; 2 Unrooted Gene Trees; 3 Rooted rRNA and Protein Trees; 4 The Unholy Sanctity of Genotype; 5 More Than One Way to Skin a Genome; 5.1 The Dimensionality of Molecular Phenotypes; 6 Phylogenies of Protein Domains; 7 Preserving the Purity of the Lineage; 8 Novel Protein Discovery; 9 Akaryotes: Less Is More; 10 No Genome Is an Island; 11 Darwin Rules 000856318 5058_ $$a4.2 The Pandora Box of New Archaeal and Bacterial Lineages4.3 The Conundrum of Fast-Evolving Species; 4.4 The Problem of Contamination in TOL Analyses; 4.5 Contradictory Signals in Protein Datasets; 4.6 TOLs Based on RNA Polymerase; 4.7 The Archaeal Root; 4.8 Where Are the Viruses in the TOL?; 5 Perspectives; 6 Conclusion; References; Chapter 4: Multiple Clocks in the Evolution of Living Organisms; 1 Introduction; 2 Prologue: Against Any Singular Origin in General Physical Processes; 2.1 No Eve, No Adam; 2.2 Multiple Origins of the First Cells; 3 The Master Functions of Life 000856318 5058_ $$a4 Horizontal Gene Transfer5 Microbial Genomes Organisation; 6 The Making of a Progeny; 7 Evolution of Resting Cells Progeny; 8 Provisional Conclusion: No Universal Molecular Clock; References; Chapter 5: Natural Strategies of Spontaneous Genetic Variation: The Driving Force of Biological Evolution; References; Chapter 6: The Evolution of Gene Regulatory Mechanisms in Bacteria; 1 Introduction; 2 The Emergence and Evolution of RNA Polymerase; 2.1 Alternative Sigma Factors of RNA Polymerase; 3 Transcription and Its Regulation; 3.1 Promoter Architecture and Transcription Regulation 000856318 506__ $$aAccess limited to authorized users. 000856318 588__ $$aOnline resource; title from PDF title page (viewed October 17, 2018). 000856318 650_0 $$aMicroorganisms$$xEvolution. 000856318 650_0 $$aMolecular dynamics. 000856318 7001_ $$aRampelotto, Pabulo H.,$$eeditor. 000856318 77608 $$iPrint version: $$z3319690779$$z9783319690773$$w(OCoLC)1004070088 000856318 830_0 $$aGrand challenges in biology and biotechnology. 000856318 852__ $$bebk 000856318 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-69078-0$$zOnline Access$$91397441.1 000856318 909CO $$ooai:library.usi.edu:856318$$pGLOBAL_SET 000856318 980__ $$aEBOOK 000856318 980__ $$aBIB 000856318 982__ $$aEbook 000856318 983__ $$aOnline 000856318 994__ $$a92$$bISE