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000856405 020__ $$a9783319993195$$q(electronic book)
000856405 020__ $$a3319993194$$q(electronic book)
000856405 020__ $$z9783319993188
000856405 035__ $$aSP(OCoLC)on1062395479
000856405 035__ $$aSP(OCoLC)1062395479
000856405 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dOCLCO$$dEBLCP$$dGW5XE$$dOCLCF$$dUKMGB$$dYDXIT
000856405 049__ $$aISEA
000856405 050_4 $$aQH588.S83$$bG47 2018
000856405 08204 $$a616.02/774$$223
000856405 1001_ $$aGerecht, Sharon,$$eauthor.
000856405 24510 $$aBiophysical regulation of vascular differentiation and assembly /$$cSharon Gerecht, editor.
000856405 250__ $$aSecond Edition.
000856405 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2018]
000856405 300__ $$a1 online resource (ix, 195 pages).
000856405 336__ $$atext$$btxt$$2rdacontent
000856405 337__ $$acomputer$$bc$$2rdamedia
000856405 338__ $$aonline resource$$bcr$$2rdacarrier
000856405 4901_ $$aBiological and medical physics, biomedical engineering
000856405 504__ $$aIncludes bibliographical references and index.
000856405 5050_ $$aIntro; Dedication; Preface; Contents; Chapter 1: Molecular Control of Capillary Tube Morphogenesis and Maturation Through Endothelial Cell-Pericyte Interactions: Regulation by Small GTPase-Mediated Signaling, Kinase Cascades, Extracellular Matrix Remodeling, and Defined Growth Factors; 1.1 Introduction; 1.2 Concepts in Vascular Tube Morphogenesis in 3D Extracellular Matrices; 1.2.1 Extracellular Matrix and Vascular Morphogenesis; 1.2.2 Differential Effects of ECM Components on Vascular Tube Morphogenesis; 1.3 Review of Work
000856405 5058_ $$a1.3.6 Key Role for Polarized Subapical Microtubule Modifications to Direct the Trafficking and Fusion of Pinocytic Vacuoles to Regulate Apical Membrane Development During EC Lumen Formation1.3.7 Critical Functional Role for MT1-MMP in EC Lumen and Tube Formation in 3D Collagen Matrices; 1.3.8 MT1-MMP-Dependent EC Lumen and Tube Formation Leads to the Formation of a Network of Physical Spaces Within the ECM Termed Vascular Guidance Tunnels
000856405 5058_ $$a1.3.9 Cdc42 and MT1-MMP Are Functionally Interdependent Signaling Molecules Which Are Components of an EC Lumen Signaling Complex that Controls EC Tubulogenesis in 3D Extracellular Matrices1.3.10 Critical Role for MMPs in the Molecular Control of Vascular Tube Regression Responses in 3D Collagen Matrices; 1.3.11 Critical Functional Role for EC-Generated Vascular Guidance Tunnels During Blood Vessel Assembly in 3D Matrices; 1.3.12 Pericyte Recruitment to Vascular Guidance Tunnels Induces Vascular Tube Stabilization
000856405 5058_ $$a1.3.13 Molecular Mechanisms Underlying Why Pericytes Are Able to Stabilize EC-Lined Tube Networks1.3.14 Pericyte Recruitment to EC-Lined Tubes Stimulates ECM Remodeling Events and Vascular Basement Membrane Matrix Assembly; 1.3.15 Critical Functional Role for Fibronectin Matrix Assembly During Vascular Development; 1.3.16 Important Functional Role for Collagen Type IV in EC-Pericyte Tube Co-Assembly and Maturation Events; 1.3.17 Pericyte TIMP-3 Contributes to Vascular Basement Membrane Matrix Assembly by Increasing Collagen Type IV Deposition or Stability
000856405 506__ $$aAccess limited to authorized users.
000856405 520__ $$aUnderstanding stem cell differentiation is a key step on the road to unlocking the cells' therapeutic potential. This book shows how microenvironmental factors regulate the differentiation and assembly of stem cells that develop into functional vasculature.
000856405 588__ $$aDescription based on online resource; title from digital title page (viewed on December 28, 2018).
000856405 650_0 $$aStem cells.
000856405 650_0 $$aBlood-vessels$$xGrowth.
000856405 650_0 $$aBiophysics.
000856405 650_0 $$aBiomedical engineering.
000856405 830_0 $$aBiological and medical physics, biomedical engineering.
000856405 852__ $$bebk
000856405 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-99319-5$$zOnline Access$$91397441.1
000856405 909CO $$ooai:library.usi.edu:856405$$pGLOBAL_SET
000856405 980__ $$aEBOOK
000856405 980__ $$aBIB
000856405 982__ $$aEbook
000856405 983__ $$aOnline
000856405 994__ $$a92$$bISE