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Intro; Foreword; Preface; Acknowledgments; Introduction; Contents; Contributors; Part I: Translational Research; 1: Neuroanatomy of the Trigeminal Nerve and Proximal Innervation of the TMJ; 1.1 Introduction; 1.1.1 Neuroanatomy of the Temporomandibular Joint; 1.1.1.1 Temporomandibular Joint and Trigeminal Nerve Connections; 1.1.2 Anatomy and Physiology of the Trigeminal Nerve and Its Central Connections; 1.1.3 Ophthalmic Nerve; 1.1.4 Maxillary Nerve; 1.1.5 Mandibular Nerve; 1.1.6 Otic Ganglion; 1.1.6.1 Anterior Division of V3; 1.1.6.2 Posterior Division of V3

1.1.7 Trigeminal Afferent Fibers1.1.8 Gasserian (Trigeminal, Semilunar) Ganglion; 1.1.9 Trigeminal Nerve Nuclei; 1.1.9.1 Main Sensory Nucleus; 1.1.9.2 Mesencephalic Nucleus; 1.1.9.3 Spinal Trigeminal Nucleus; 1.1.9.4 Trigeminal Motor Nucleus; 1.1.10 Spinal Trigeminal Nuclei Connections; 1.1.11 Reticular Formation; 1.1.12 Thalamus; 1.1.13 Auriculotemporal Nerve Connection to Systemic Neuropathology; References; 2: Neuroanatomy and Neurophysiology of the Trigeminal Network System; 2.1 Cranial Nerve Involvement in TMD; 2.2 The Somatosensory Receptors of the Human Oral Tissues

2.2.1 Mechanoreceptors2.2.2 Nociceptors; 2.2.3 Thermoreceptors; 2.3 Gasserian Ganglion; 2.4 Branches of Trigeminal Nerve; 2.4.1 Ophthalmic Nerve; 2.4.2 Maxillary Nerve; 2.4.3 Mandibular Nerve; 2.4.3.1 Auriculotemporal (AT) Nerve; 2.5 Innervation of Cranial Dura Mater and Trigeminal Nerve; 2.6 Trigeminal Innervation of Major Intracranial Vessels; 2.7 Trigeminal Nerve (CN V) Pathways; 2.7.1 Motor Nucleus of the Trigeminal; 2.7.2 Sensory Nuclei; 2.7.3 Main Nucleus; 2.7.4 Mesencephalic; 2.7.5 Spinal Trigeminal Nucleus; 2.8 Trigeminal Nerve-Related Cranial Nerve Pathways

2.8.1 Facial Nerve2.8.2 Glossopharyngeal Nerve; 2.8.3 Vagus Nerve (CN X); 2.9 Neurophysiological Pathway Correspondence; 2.9.1 Trigeminofacial Reflex; 2.9.2 Trigeminocervical Reflex; 2.9.3 Trigeminocardiac Reflex; 2.9.4 Tonic Neck Reflex; References; 3: Neuroimmune and Systemic Manifestations of Neuroinflammation in the Temporomandibular Joint and Related Disorders; 3.1 Introduction; 3.2 Research and Findings; 3.3 Immune Surveillance and Signaling, Tissue Reaction, and Inflammation; 3.4 Blood-Brain Barrier (BBB) Disruption and Inflammation

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