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Biological mechanisms of minimal residual disease and systemic cancer / Julio A. Aguirre-Ghiso, editor.

Aguirre-Ghiso, Julio A., editor.
2018
RC268.4
Available Online
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Title
Biological mechanisms of minimal residual disease and systemic cancer / Julio A. Aguirre-Ghiso, editor.
ISBN
9783319977461 (electronic book)
3319977466 (electronic book)
9783319977454
3319977458
9783319977454
DOI
https://doi.org/10.1007/978-3-319-97746-1
Published
Cham, Switzerland : Springer, [2018]
Copyright
©2018
Language
English
Description
1 online resource (ix, 162 pages) : illustrations (chiefly color).
Item Number
10.1007/978-3-319-97746-1 doi
Call Number
RC268.4
Dewey Decimal Classification
616.99/4
Summary
"This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic insights. Chapters in solid and hematological malignancies address stem cell biology, genetics, epigenetics and micro-environmental regulation of dormant MRD. Novel insight into technologies for molecular phenotyping of MRD and monitoring of CTCs, DTCs and cell free RNA and DNA are also addressed extensively. Five chapters explore the above concepts in solid cancers such as prostate, breast, melanoma, head and neck and esophageal. Two chapters also explore the basic mechanisms of vascular biology targeting and epigenetic mechanisms regulating pluripotency programs during dormancy. Similar biology is explored in hematological malignancies such as T-ALL, CML, AML and multiple myeloma in additional four chapters"--Publisher's description.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Description based on online resource; title from electronic title page (SpringerLink, viewed November 27, 2018).
Added Author
Aguirre-Ghiso, Julio A., editor.
Series
Advances in experimental medicine and biology ; v. 1100. 0065-2598
Available in Other Form
Biological mechanisms of minimal residual disease and systemic cancer.
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Record Appears in
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