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000856593 019__ $$a1079828049
000856593 020__ $$a9783030037420$$q(electronic book)
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000856593 0247_ $$a10.1007/978-3-030-03742-0$$2doi
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000856593 24500 $$aTrace elements and minerals in health and longevity /$$cMarco Malavolta, Eugenio Mocchegiani, editors.
000856593 260__ $$aCham :$$bSpringer,$$c2018.
000856593 300__ $$a1 online resource (332 pages).
000856593 336__ $$atext$$btxt$$2rdacontent
000856593 337__ $$acomputer$$bc$$2rdamedia
000856593 338__ $$aonline resource$$bcr$$2rdacarrier
000856593 347__ $$atext file$$bPDF$$2rda
000856593 4901_ $$aHealthy Ageing and Longevity ;$$vvolume 8
000856593 5050_ $$aIntro; Preface; Acknowledgements; Contents; 1 Iron; 1.1 Introduction; 1.2 Iron Homeostasis Regulation; 1.3 Iron and Age Related Conditions and Diseases; 1.3.1 Iron and Cancer; 1.3.2 Iron and Atherosclerosis; 1.3.3 Iron and Cardiovascular Diseases; 1.3.4 Iron and Brain Diseases; 1.3.5 Iron and Obesity Related Disorders; 1.4 Iron Deficiency; 1.5 Recommended Iron Intake for Longevity in the Elderly; 1.6 Interaction of Iron with Drugs Prescribed in the Elderly; 1.6.1 Medications Which Absorption Can Be Decreased by Iron; 1.6.2 Medications that Decrease Iron Absorption.
000856593 5058_ $$a1.6.3 Medication that Increase Blood Iron Levels1.7 Iron and Species Lifespan Studies; 1.8 Conclusion; References; 2 Copper; 2.1 Introduction; 2.2 Intestinal and Hepatic Tissues Determine Whole-Body Copper Distribution; 2.3 Recommended Dietary Intake of Copper; 2.4 Essentiality, Deficiency, and Intake Related to Aging; 2.4.1 Copper Deficiency and Oxidative Stress Protection During Ageing; 2.4.2 Copper Deficiency and Inflammatory/Immune Response During Ageing; 2.4.3 Copper and Central Nervous System; 2.5 Copper and Species Longevity; 2.5.1 Yeasts; 2.5.2 Flies, Worms and Rotifers; 2.5.3 Mice.
000856593 5058_ $$a2.5.4 Cellular Senescence: In Vitro Models2.6 New Technology to Study the Role of Copper on the Ageing; 2.7 Copper Toxicity; 2.7.1 Excess/Toxicity and Age-Related Disease: Childhood and Ageing; 2.7.2 Neurodegenerative Diseases; 2.7.3 Treatments to Combat Metal Overload; 2.8 New Perspectives in Copper and Ageing; 2.9 Conclusive Remarks; References; 3 Selenium; 3.1 Introduction; 3.2 Selenium in the Environment; 3.3 Selenium in Human and Animal Nutrition; 3.3.1 Need for Selenium in Humans; 3.3.2 Source of Selenium in Human Diet; 3.3.3 Endemic Diseases Related to Selenium Deficiency.
000856593 5058_ $$a3.4 Metabolism of Selenium in the Organism3.4.1 Selenium Absorption, Distribution in the Tissues and Excretion; 3.4.2 Synthesis of Selenoproteins; 3.5 The Major Selenoproteins and Their Functions; 3.5.1 Glutathione Peroxidases; 3.5.2 Thioredoxin Reductases; 3.5.3 Iodothyronine Deiodinases; 3.5.4 Selenophosphate Synthethase 2; 3.5.5 Selenoprotein P; 3.5.6 Methionine-R-Sulfoxide Reductase (Selenoprotein R); 3.5.7 Effects of Dietary Selenium on Selenoprotein Levels; 3.6 Biological Functions of Selenium in Humans and Animals; 3.6.1 Selenium and the Immune Function.
000856593 5058_ $$a3.6.2 Selenium and Viral Infection3.6.3 Selenium and Thyroid Function; 3.6.4 Selenium and Brain Function; 3.6.5 Selenium and Fertility; 3.6.6 Selenium and Cardiovascular Disease; 3.6.7 Role of Selenium in Detoxification of Harmful Substances; 3.6.8 Effect of Selenium on Diabetes Risk; 3.6.9 Selenium and Cancer Risk; 3.7 Health Effects of Excess Selenium; 3.7.1 Selenium Toxicity and Tolerable Upper Level of Selenium Intake; 3.7.2 Mechanisms of Selenium Toxicity; 3.8 Selenium and Longevity; 3.8.1 Selenium Intake and Mortality Risk; 3.8.2 Selenium and Aging; 3.8.3 Selenium and Longevity; 3.9 Conclusions.
000856593 506__ $$aAccess limited to authorized users.
000856593 520__ $$aThis book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
000856593 588__ $$aDescripition based on print version record.
000856593 650_0 $$aTrace elements in nutrition.
000856593 650_0 $$aAging$$xNutritional aspects.
000856593 7001_ $$aMalavolta, Marco.
000856593 7001_ $$aMocchegiani, Eugenio.
000856593 77608 $$iPrint version:$$aMalavolta, Marco.$$tTrace Elements and Minerals in Health and Longevity.$$dCham : Springer, ©2018$$z9783030037413
000856593 830_0 $$aHealthy ageing and longevity ;$$vv. 8.
000856593 852__ $$bebk
000856593 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-03742-0$$zOnline Access$$91397441.1
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