Metabotropic GPCRs : TGR5 and P2Y receptors in health and diseases / Senthilkumar Rajagopal, Murugavel Ponnusamy.
Rajagopal, Senthilkumar, author.; Ponnusamy, Murugavel, author.
2018
QP552.G16
Available Online

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Title Metabotropic GPCRs : TGR5 and P2Y receptors in health and diseases / Senthilkumar Rajagopal, Murugavel Ponnusamy.
Author Rajagopal, Senthilkumar, author.
ISBN 9789811315718 (electronic book)
981131571X (electronic book)
9789811315701
DOI https://doi.org/10.1007/978-981-13-1571-8
Published Singapore : Springer, 2018.
Language English
Description 1 online resource (xii, 76 pages) : illustrations
Other Standard Identifiers 10.1007/978-981-13-1571-8 doi
Call Number QP552.G16
Dewey Decimal Classification 572/.696
Summary This book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Digital File Characteristics text file PDF
Source of Description Online resource; title from PDF title page (SpringerLink, viewed November 30, 2018).
Added Author Ponnusamy, Murugavel, author.
Available in Other Form Print version: 9789811315701
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Module 1. Overview of G-Protein coupled receptor
Module 2. TGR5 receptor
Module 3. P2Y receptor
Module 4. Therapeutically Targeting TGR5 & P2Y receptors. .

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