000856691 000__ 02899cam\a2200457Ii\4500 000856691 001__ 856691 000856691 005__ 20230306145149.0 000856691 006__ m\\\\\o\\d\\\\\\\\ 000856691 007__ cr\un\nnnunnun 000856691 008__ 181130s2018\\\\si\a\\\\ob\\\\000\0\eng\d 000856691 019__ $$a1079789496 000856691 020__ $$a9789811315718$$q(electronic book) 000856691 020__ $$a981131571X$$q(electronic book) 000856691 020__ $$z9789811315701 000856691 0247_ $$a10.1007/978-981-13-1571-8$$2doi 000856691 035__ $$aSP(OCoLC)on1076575669 000856691 035__ $$aSP(OCoLC)1076575669$$z(OCoLC)1079789496 000856691 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dDKU 000856691 049__ $$aISEA 000856691 050_4 $$aQP552.G16 000856691 08204 $$a572/.696$$223 000856691 1001_ $$aRajagopal, Senthilkumar,$$eauthor. 000856691 24510 $$aMetabotropic GPCRs :$$bTGR5 and P2Y receptors in health and diseases /$$cSenthilkumar Rajagopal, Murugavel Ponnusamy. 000856691 264_1 $$aSingapore :$$bSpringer,$$c2018. 000856691 300__ $$a1 online resource (xii, 76 pages) :$$billustrations 000856691 336__ $$atext$$btxt$$2rdacontent 000856691 337__ $$acomputer$$bc$$2rdamedia 000856691 338__ $$aonline resource$$bcr$$2rdacarrier 000856691 347__ $$atext file$$bPDF$$2rda 000856691 504__ $$aIncludes bibliographical references. 000856691 5050_ $$aModule 1. Overview of G-Protein coupled receptor -- Module 2. TGR5 receptor -- Module 3. P2Y receptor -- Module 4. Therapeutically Targeting TGR5 & P2Y receptors. . 000856691 506__ $$aAccess limited to authorized users. 000856691 520__ $$aThis book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members. 000856691 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed November 30, 2018). 000856691 650_0 $$aG proteins$$xReceptors. 000856691 7001_ $$aPonnusamy, Murugavel,$$eauthor. 000856691 77608 $$iPrint version: $$z9789811315701 000856691 852__ $$bebk 000856691 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-981-13-1571-8$$zOnline Access$$91397441.1 000856691 909CO $$ooai:library.usi.edu:856691$$pGLOBAL_SET 000856691 980__ $$aEBOOK 000856691 980__ $$aBIB 000856691 982__ $$aEbook 000856691 983__ $$aOnline 000856691 994__ $$a92$$bISE