000856855 000__ 04727cam\a2200457Ii\4500
000856855 001__ 856855
000856855 005__ 20230306145156.0
000856855 006__ m\\\\\o\\d\\\\\\\\
000856855 007__ cr\un\nnnunnun
000856855 008__ 181212s2018\\\\sz\a\\\\o\\\\\000\0\eng\d
000856855 019__ $$a1079836003
000856855 020__ $$a9783319995939$$q(electronic book)
000856855 020__ $$a3319995936$$q(electronic book)
000856855 020__ $$z9783319995922
000856855 0247_ $$a10.1007/978-3-319-99593-9$$2doi
000856855 035__ $$aSP(OCoLC)on1078783272
000856855 035__ $$aSP(OCoLC)1078783272$$z(OCoLC)1079836003
000856855 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dDKU
000856855 049__ $$aISEA
000856855 050_4 $$aRM301.5
000856855 08204 $$a615.7$$223
000856855 24500 $$aADME processes in pharmaceutical sciences :$$bdosage, design, and pharmacotherapy success /$$cAlan Talevi, Pablo A. M. Quiroga, editors.
000856855 264_1 $$aCham, Switzerland :$$bSpringer,$$c2018.
000856855 300__ $$a1 online resource (x, 362 pages) :$$billustrations
000856855 336__ $$atext$$btxt$$2rdacontent
000856855 337__ $$acomputer$$bc$$2rdamedia
000856855 338__ $$aonline resource$$bcr$$2rdacarrier
000856855 347__ $$atext file$$bPDF$$2rda
000856855 5050_ $$aPart 1 The Basics of ADME Processes -- Introduction ADME Processes and Their Relationship with Pharmaceutical Practice -- Drug Release -- Drug Adsorption -- Drug Excretion.-Routes of Administration -- Part 2 The Importance of ADME Properties in Burgeoning Pharmaceutical Topics -- Nanotechnology and Drug Delivery -- Pharmacogenomics and Indiviualized Therapy -- Bioavailability and Bioequivalence Studies -- The Absorption and Distribution of Biopharmaceuticals/Biological Medical Products -- Drug-Drug and Food-Drug Interactions of Pharmacokinetic Nature -- In silico and In vitro ADME prediction -- Drug Transporters and Multi-drug Resistance.
000856855 506__ $$aAccess limited to authorized users.
000856855 520__ $$aAbsorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. As an introduction oriented to pharmacy students, it is also written for scientist from different fields outside of pharmaceutics. (e.g. material scientist, material engineers, medicinal chemists) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and some biological background. Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies add valuable teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, and in silico and in vitro prediction of ADME properties. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and was written with leading experts on the correspondent topic, including scientists and academics from USA and UK (Duquesne University School of Pharmacy, Indiana University School of Medicine, University of Utah College of Pharmacy, University of Maryland, University of Bath). Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations (e.g. importance of active absorption of levodopa, implications in levodopa administration, drug drug interactions and food drug interactions emerging from the active uptake; intoxication with paracetamol as a result of glutathione depletion, CYP induction and its relationship with acute liver failure caused by paracetamol, etc). ADME Processes and Pharmaceutical Sciences is written as a core textbook for ADME processes, pharmacy, pharmacokinetics, drug delivery, biopharmaceutics, drug disposition, drug design and medicinal chemistry courses.
000856855 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 12, 2018).
000856855 650_0 $$aPharmacokinetics.
000856855 650_0 $$aPharmacology.
000856855 7001_ $$aTalevi, Alan,$$eeditor.
000856855 7001_ $$aQuiroga, Pablo A. M.$$eeditor.
000856855 77608 $$iPrint version: $$z9783319995922
000856855 852__ $$bebk
000856855 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-99593-9$$zOnline Access$$91397441.1
000856855 909CO $$ooai:library.usi.edu:856855$$pGLOBAL_SET
000856855 980__ $$aEBOOK
000856855 980__ $$aBIB
000856855 982__ $$aEbook
000856855 983__ $$aOnline
000856855 994__ $$a92$$bISE