000857650 000__ 03408cam\a2200493Mi\4500 000857650 001__ 857650 000857650 005__ 20230306145308.0 000857650 006__ m\\\\\o\\d\\\\\\\\ 000857650 007__ cr\un\nnnunnun 000857650 008__ 190105s2018\\\\sz\\\\\\o\\\\\000\0\eng\d 000857650 019__ $$a1080647597 000857650 020__ $$a9783319896236$$q(electronic book) 000857650 020__ $$a3319896237$$q(electronic book) 000857650 020__ $$z9783319896229 000857650 020__ $$z3319896229 000857650 035__ $$aSP(OCoLC)on1080999208 000857650 035__ $$aSP(OCoLC)1080999208$$z(OCoLC)1080647597 000857650 040__ $$aEBLCP$$beng$$erda$$cEBLCP$$dYDX$$dGW5XE$$dNOC 000857650 049__ $$aISEA 000857650 050_4 $$aQP535.C3 000857650 08204 $$a571.9/54662$$223 000857650 24500 $$aCadmium Interaction with Animal Cells /$$cFrank Thévenod, David Petering, Douglas M. Templeton, Wing-Kee Lee, Andrea Hartwig, editors. 000857650 264_1 $$aCham :$$bSpringer,$$c2018. 000857650 300__ $$a1 online resource (131 pages) 000857650 336__ $$atext$$btxt$$2rdacontent 000857650 337__ $$acomputer$$bc$$2rdamedia 000857650 338__ $$aonline resource$$bcr$$2rdacarrier 000857650 5050_ $$aIntro; Preface; References; Contents; 1 Membrane Transport Proteins and Receptors for Cadmium and Cadmium Complexes; 1.1 Introduction; 1.2 Channels and Pores; 1.2.1 Ca2+ Channels; 1.2.2 Mitochondrial Calcium Uniporter (MCU); 1.2.3 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR/ABCC7); 1.2.4 Gap Junction-Forming Connexins; 1.3 Solute Carriers (SLCs); 1.3.1 Divalent Metal Transporter 1 (DMT1/DCT1/NRAMP2/SLC11A2); 1.3.2 Zip8/Zip14 (SLC39A8/A14); 1.3.3 Organic Cation Transporter 2 (SLC22A2) and Multi-antimicrobial Extrusion (MATE) Proteins (SLC47A1/A2) 000857650 5058_ $$a1.3.4 Amino Acid/Cystine Transporter (SLC7A9/SLC3A1)1.3.5 Ferroportin-1 (FPN1/SLC40A1); 1.4 ATPASES; 1.4.1 Multidrug Resistance P-Glycoprotein (MDR1/ABCB1); 1.4.2 Multidrug Resistance-Associated Protein 1 (MRP1/ABCC1); 1.5 Receptors; 1.5.1 Lipocalin-2 Receptor (Lip2-R/SLC22A17); 1.5.2 Megalin: Cubilin; 1.5.3 Transferrin Receptor 1 (TfR1); 1.6 Summary, Conclusions and Outlook; References; 2 The Chemical Biology of Cadmium; 2.1 Introduction; 2.2 Inorganic Biochemical Framework for Cd2+ Toxicology; 2.3 Metallothionein and the Proteome: Reactions with Cd2+ and Zn2+ 000857650 5058_ $$a2.4 MTF-1: Reactions with Cd2+ and Zn2+2.5 Reactions of Cd2+ with Metallothionein in Relation to Animal Toxicity; 2.6 Reactions of Cd2+ with Zn-Proteins in Relation to Nephrotoxicity: Zn3-SP1; 2.7 Reactions of Cd2+ with Zn-Proteins in Relation to Carcinogenesis; 2.8 Reactions of Cd2+ Related to Apoptosis; 2.9 Reactions of Cd2+ with Zn-Proteins in Relation to Signal Transduction; 2.10 Interactions of Cd2+ with Iron, Copper, and Calcium; 2.11 Analytical Methodology to Detect Cd-Proteins; References; 3 Interactions of Cadmium with Signaling Molecules; 3.1 Introduction 000857650 506__ $$aAccess limited to authorized users. 000857650 588__ $$aDescription based on print version record. 000857650 650_0 $$aCadmium$$xPhysiological effect. 000857650 650_0 $$aCadmium$$xToxicology. 000857650 7001_ $$aThévenod, F.$$q(Frank) 000857650 7001_ $$aPetering, David. 000857650 7001_ $$aTempleton, Douglas M. 000857650 7001_ $$aLee, Wing-Kee. 000857650 7001_ $$aHartwig, Andrea. 000857650 77608 $$iPrint version:$$aThévenod, Frank$$tCadmium Interaction with Animal Cells$$dCham : Springer,c2018$$z9783319896229 000857650 852__ $$bebk 000857650 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-89623-6$$zOnline Access$$91397441.1 000857650 909CO $$ooai:library.usi.edu:857650$$pGLOBAL_SET 000857650 980__ $$aEBOOK 000857650 980__ $$aBIB 000857650 982__ $$aEbook 000857650 983__ $$aOnline 000857650 994__ $$a92$$bISE