000857653 000__ 04133cam\a2200505Mu\4500 000857653 001__ 857653 000857653 005__ 20230306145308.0 000857653 006__ m\\\\\o\\d\\\\\\\\ 000857653 007__ cr\un\nnnunnun 000857653 008__ 190105s2018\\\\xx\\\\\\o\\\\\000\0\eng\d 000857653 020__ $$a9783030005962$$q(electronic book) 000857653 020__ $$a3030005968$$q(electronic book) 000857653 020__ $$z9783030005955 000857653 035__ $$aSP(OCoLC)on1080999365 000857653 035__ $$aSP(OCoLC)1080999365 000857653 040__ $$aEBLCP$$beng$$cEBLCP$$dGW5XE 000857653 049__ $$aISEA 000857653 050_4 $$aQH657$$b.B73 2018eb 000857653 08204 $$a571.435$$223 000857653 1001_ $$aHanke, Wolfgang. 000857653 24510 $$aGravitational Biology II :$$bInteraction of Gravity with Cellular Components and Cell Metabolism /$$cWolfgang Hanke [and more]. 000857653 260__ $$aCham :$$bSpringer,$$c2018. 000857653 300__ $$a1 online resource (108 pages) 000857653 336__ $$atext$$btxt$$2rdacontent 000857653 337__ $$acomputer$$bc$$2rdamedia 000857653 338__ $$aonline resource$$bcr$$2rdacarrier 000857653 4901_ $$aSpringerBriefs in Space Life Sciences Ser. 000857653 5050_ $$aIntro; Preface to the Series; Preface; Acknowledgements; Contents; Chapter 1: Interaction of Gravity with Cellular Compounds; 1.1 Introduction; 1.2 Structure and Function of the Neuronal System; 1.3 Biological Membranes; 1.4 Neuronal Cells; 1.5 Thermodynamics of Neuronal Systems; 1.6 Interaction of Gravity with Single Molecules; 1.7 Interaction of Gravity with Membranes; 1.8 Interaction of Gravity with Neuronal Cells; 1.9 Membrane Potential; 1.10 Action Potentials; 1.11 Cytosolic Calcium Concentration; 1.12 Discussion and Consequences; 1.13 Modeling the Gravity Dependence of Neuronal Tissue 000857653 5058_ $$a1.14 Space Pharmacology1.15 Outlook and Future Perspectives; References; Chapter 2: Interaction of Gravity with Cell Metabolism; 2.1 Introduction; 2.2 Methods; 2.2.1 Opportunities for Exposure; 2.2.1.1 Centrifugation; 2.2.1.2 Clinorotation; 2.2.1.3 Random Positioning; 2.2.1.4 Magnetic Levitation; 2.2.1.5 Space Shuttle and Satellite; 2.2.1.6 Sounding Rockets; 2.2.1.7 Parabolic Flights: Hyper-g, Partial g, and Microgravity; 2.2.2 Plant Material; 2.2.3 Determination of Key Metabolites; 2.2.4 Metabolic Labeling with (14C)-Glucose; 2.2.5 Real-Time Analysis of Ca2+ and Hydrogen Peroxide 000857653 5058_ $$a2.2.6 Gene and Protein Expression2.3 Results; 2.3.1 Metabolism; 2.3.2 Secondary Messengers: Calcium and Hydrogen Peroxide; 2.3.3 Gene Expression; 2.3.3.1 Expression of Genes Coding for Primary Metabolism; 2.3.3.2 Expression of Genes Coding for Transcription Factors; Time-Course Experiments: Hyper-g and Simulation of Microgravity; Effects of Microgravity: MAXUS 7; Functions of TFs; 2.3.3.3 Conclusion for Transcription Factor Studies; 2.3.4 Array Studies; 2.3.4.1 Macroarrays (``Home Made)́́; 2.3.4.2 Early Microarrays (Incyte Genomics); 2.3.4.3 Affymetrix Microarrays; 2.3.5 Platforms 000857653 5058_ $$a2.3.6 Protein Expression and Modulation2.3.6.1 Hypergravity; 2.3.6.2 2-D Clinorotation; 2.3.6.3 Random Positioning; Phosphoproteom; Two-dimensional SDS Polyacrylamide Gel Electrophoresis; 2.3.6.4 Protein Labeling; 2.3.6.5 Evaluation of Simulation of Microgravity; 2.3.6.6 How We Think that a Gravity-Related Line of Plant Responses Works: Secondary Messengers, Genes, and Proteins; ROS Scavenging and Detoxifying Enzymes; Signal Transduction; Metabolism; Protein Translation and Proteolysis; Cell Wall Biosynthesis; Ion homeostasis; 2.4 Conclusions; References 000857653 506__ $$aAccess limited to authorized users. 000857653 588__ $$aDescription based on print version record. 000857653 650_0 $$aGravity$$xPhysiological effect. 000857653 650_0 $$aMicroorganisms. 000857653 650_0 $$aBiotechnological microorganisms. 000857653 7001_ $$aKohn, Florian P. M. 000857653 7001_ $$aNeef, Maren. 000857653 7001_ $$aHampp, Rüdiger. 000857653 77608 $$iPrint version:$$aHanke, Wolfgang$$tGravitational Biology II : Interaction of Gravity with Cellular Components and Cell Metabolism$$dCham : Springer,c2018$$z9783030005955 000857653 830_0 $$aSpringerBriefs in space life sciences. 000857653 852__ $$bebk 000857653 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-00596-2$$zOnline Access$$91397441.1 000857653 909CO $$ooai:library.usi.edu:857653$$pGLOBAL_SET 000857653 980__ $$aEBOOK 000857653 980__ $$aBIB 000857653 982__ $$aEbook 000857653 983__ $$aOnline 000857653 994__ $$a92$$bISE