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000858180 020__ $$a9783030027711$$q(electronic book)
000858180 020__ $$a3030027716$$q(electronic book)
000858180 020__ $$z9783030027704
000858180 0247_ $$a10.1007/978-3-030-02771-1$$2doi
000858180 035__ $$aSP(OCoLC)on1083217583
000858180 035__ $$aSP(OCoLC)1083217583
000858180 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dUKMGB$$dUAB
000858180 049__ $$aISEA
000858180 050_4 $$aRC280.C6
000858180 08204 $$a616.99/4347061$$223
000858180 24500 $$aTargeted therapy of colorectal cancer subtypes /$$cPeter Jordan, editor.
000858180 264_1 $$aCham, Switzerland :$$bSpringer,$$c2018.
000858180 300__ $$a1 online resource (viii, 150 pages) :$$billustrations.
000858180 336__ $$atext$$btxt$$2rdacontent
000858180 337__ $$acomputer$$bc$$2rdamedia
000858180 338__ $$aonline resource$$bcr$$2rdacarrier
000858180 4901_ $$aAdvances in experimental medicine and biology,$$x0065-2598 ;$$vvolume 1110
000858180 500__ $$aIncludes index.
000858180 5050_ $$aPreface Chapter 1- Colorectal Cancer Subtypes- the current portrait. 1 Peter Jordan Chapter 2- Targeting colon cancers with mutated BRAF and microsatellite instability. 17 Paulo Matos and Peter Jordan Chapter 3 -- Targeting KRAS mutant CMS3 subtype by metabolic inhibitors. 50 Oscar Aguilera and Roberto Serna-Blasco Chapter 4- Targeting the PI3K Signalling as a Therapeutic Strategy in Colorectal Cancer. 77 Maria Sofia Fernandes, João Miguel Sanches and Raquel Seruca Chapter 5- Targeting PTEN in colorectal cancers. 117 Larissa Kotelevets, Mark G.H. Scott and Eric Chastre Chapter 6- Wnt signalling-targeted therapy in the CMS2 tumour subtype: a new paradigm in CRC treatment? 162 Cristina Albuquerque and Lucília Pebre Pereira Chapter 7- Impact of the microenvironment on tumour budding in colorectal cancer. 216 Laurent MC Georges, Laurine Verset, Inti Zlobec, Pieter Demetter, Olivier De Wever Chapter 8- Anti-EGFR Therapy to treat metastatic colorectal cancer: not for all 241 Marta Martins, André Mansinho, Raquel Duarte, Soraia Lobo Martins and Luís Costa Chapter 9- miRNAs as modulators of EGFR therapy in colorectal cancer. 282 Diane M. Pereira and Cecília M. P. Rodrigues Index.
000858180 506__ $$aAccess limited to authorized users.
000858180 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 23, 2019).
000858180 650_0 $$aColon (Anatomy)$$xCancer$$xChemotherapy.
000858180 650_0 $$aRectum$$xCancer$$xChemotherapy.
000858180 650_0 $$aDrug targeting.
000858180 7001_ $$aJordan, Peter,$$eeditor.
000858180 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1110.
000858180 852__ $$bebk
000858180 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-030-02771-1$$zOnline Access$$91397441.1
000858180 909CO $$ooai:library.usi.edu:858180$$pGLOBAL_SET
000858180 980__ $$aEBOOK
000858180 980__ $$aBIB
000858180 982__ $$aEbook
000858180 983__ $$aOnline
000858180 994__ $$a92$$bISE