Molecular Machines presents a dynamic new approach to the physics of enzymes and DNA from the perspective of materials science. Unified around the concept of molecular deformability--how proteins and DNA stretch, fold, and change shape--this book describes the complex molecules of life from the innovative perspective of materials properties and dynamics, in contrast to structural or purely chemical approaches. It covers a wealth of topics, including nonlinear deformability of enzymes and DNA; the chemo-dynamic cycle of enzymes; supra-molecular constructions with internal stress; nano-rheology and viscoelasticity; and chemical kinetics, Brownian motion, and barrier crossing. Essential reading for researchers in materials science, engineering, and nanotechnology, the book also describes the landmark experiments that have established the materials properties and energy landscape of large biological molecules.
Bibliography, etc. Note
Includes bibliographical references (pages 165-172) and index.
