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Intro; Foreword; Preface; Contents; Contributors; Chapter 1: Tobacco and Social Justice; Introduction; The State of Worldwide Tobacco Use and the Extent of the Problem; The Legal Realm; Targeting Vulnerable Communities; Environmental Consequences of Growing Tobacco; E-Cigarettes; Tobacco and Ethics; References; Chapter 2: Climate Change and Cancer; Introduction; Climate Change, Pollution, and Lung Cancer; Wildfire Smoke; Inversions and Anthropogenic Air Pollution; Climate Change, Ultraviolet Radiation Exposure, and Skin Cancer

Cancer and Changes in the Quality and Quantity of Important Stable CropsConclusions; References; Chapter 3: Pollution, Cancer Risk, and Vulnerable Populations; Introduction; Vulnerable Populations and Cancer Prevention; Environmental Justice in a Changing Chemical Landscape; Pesticide Safety in Low-Resource Settings; Pesticide Exposure and Cancer Risk Among Farmers, Families, and Children; Focus on Ecuador: Working Through Sociopolitical Barriers to Treat Cancer Amidst a Battle Over Oil and Biodiversity in Ecuador's Amazon

Focus on Africa: The Challenge of Defining the Problem in Rwanda: Is Indoor Air Pollution a Health Hazard?Indoor Smoke/Secondhand Smoke Exposure; Conclusion; References; Chapter 4: Causes, Consequences, and Control of High Cancer Drug Prices; Cancer Drug Prices; Explanations for High Cancer Drug Prices; The Clinical Benefits and Economic Value of Cancer Drugs; The Role of the FDA; Effect of High Cancer Drug Prices on Patients; Controlling the Cost of Cancer Drugs; Negotiating Drug Prices; Biosimilars and Generics; Reducing Other Wasteful Practices

Academia or Public Involvement in Clinical TrialsRepurposing of Older/Cheaper Drugs; Academia-Led Non-inferiority Studies; Responsible Prescribing; A Note on LMICs; Conclusions; References; Chapter 5: Clinical Trials: Not for the  Poor and the Old; Introduction; Clinical Trial Participation; Significance; Costs; Generalizability; Rights; Benefit; Respect and Justice; Contributing Factors; Clinicians; Eligibility Criteria; Cost; Research Infrastructure; Patients; (Re)Solutions; Resolution; Immediate Action; Ongoing Action; Reduce, Refine, and Replace; Reduce; Refine; Replace; References

Chapter 6: Global Disparities: Can the World Afford Cancer?Introduction; Healthcare Expenditure and Cancer Care; Government Investment in Healthcare; Access to Cancer Medications, and Affordability of Cancer Care; Access to Radiation Therapy; Availability of Preventive Strategies; Improving Global Access to Cancer Care; Role of National Governments; Role of International Organizations and Trade Regulations; Generic and Biosimilar Medications; Alternative Strategies to Improve Access to Novel Therapies; Creating the Evidence Base for Reducing Drug Pricing; Conclusion; References

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