Intro; Preface; Contents; Contributors; Including Toxicity Risk in Balanced Clinical Decision Making; References; Acute and Late Skin Toxicity from Breast Radiation; The Layers of Skin and Anatomy of the Breast; Composition of the Skin; Breast Anatomy; Radiotherapy-Related Skin Toxicity in Breast Cancer; General Principals of the Radiation Response and Breast-Specific Considerations; Acute Skin Toxicities; Diagnosis and Grading of Acute Skin Toxicity; Clinical Findings of Acute Radiation Toxicity; Erythema; The Desquamation Continuum; Late Skin Toxicity

Diagnosis and Grading of Late Skin ToxicityTypes of Late Skin Toxicity; Radiation-Induced Fibrosis; Atrophy; Hyperpigmentation; Telangiectasia; Morphea; Radiation Recall; Risk Factors for Acute and Late Radiation Skin Toxicity; Patient Predisposition to Skin Toxicity; Patient Characteristics; Genetic Predisposition via Altered DNA Damage Repair; Dysfunctional Immune Response; Radiation Delivery and Planning Risk Factors; Other Non-radiation Treatment Characteristics; Management of Acute and Late Skin Toxicity; Management of Acute Toxicity; Prevention of Acute Skin Toxicity

Treatment of Acute Skin ToxicityTreatment of Late Toxicity; Considerations for Including Risk of Toxicity in Management Decisions; Conclusions and Future Directions; References; Fatigue Associated with Radiation Treatment for Breast Cancer; Introduction; Fatigue Prevalence During and After Breast Cancer Radiotherapy; Prevalence of Fatigue; Fatigue Severity; Fatigue Scales; Biological Mechanisms of Fatigue; Inflammation; Inflammation and Radiotherapy-Induced Dermatitis; Cellular Immunity; Anemia; Predictors of Fatigue; Demographic Factors; Clinical, Tumor, and Treatment-Related Factors

Behavioral SymptomsRadiation Dose, Fractionation, and Fatigue; Treatments for Fatigue; References; Pain Associated with Radiation Treatment for Breast Cancer; Introduction; Epidemiology of Pain; Etiology and Pathophysiology of Pain; Acute Pain; Prevalence and Incidence; Symptoms and Pain Location; Risk Factors; Chronic Persistent Pain; Prevalence; Risk Factors; Delayed Radiation-Induced Brachial Plexus Neuropathy (RIBPN); Incidence/Prevalence; Symptoms; Risk Factors; Assessment of Pain; Unidimensional Pain Scale; Multidimensional Pain Assessment; Neuropathic Pain (NP) Assessment

Management of PainAcute and Chronic Persistent Pain; The WHO Analgesic Ladder; Non-pharmacological Strategies; Neuropathic Pain (NP); Radiation-Induced Brachial Plexus Neuropathy (RIBPN); Risk Reduction; Pain Management; Conclusion; References; Considerations for Post-Mastectomy Radiation Therapy in the Setting of Breast Reconstruction; Introduction; Surgical Factors Impacting PMRT Outcomes; Patient Factors Impacting PMRT Outcomes; Radiation Planning Factors; Conclusion; References; Lymphedema After Breast Cancer Treatment; Incidence of BCRL; Detection of BCRL and Diagnostic Methods